Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survival
Patients with end-stage renal disease face a significantly higher risk of cardiovascular diseases. For patients who are candidates for renal transplantation (RT), major surgeries such as coronary artery bypass grafting (CABG) are associated with cardiac complications as well as higher rates of post-...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1486771/full |
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| author | Özge Çetinarslan Davit Saba |
| author_facet | Özge Çetinarslan Davit Saba |
| author_sort | Özge Çetinarslan |
| collection | DOAJ |
| description | Patients with end-stage renal disease face a significantly higher risk of cardiovascular diseases. For patients who are candidates for renal transplantation (RT), major surgeries such as coronary artery bypass grafting (CABG) are associated with cardiac complications as well as higher rates of post-operative complications, including the need for large amounts of blood transfusion, worsening kidney function, infection, and graft rejection. Studies have shown that blood transfusions can increase the risk of graft rejection due to immune system activation. Off-pump CABG (OPCAB), also known as beating heart surgery, is a technique in which a heart–lung machine is not used, and the heart continues to beat throughout the procedure. The main advantage of OPCAB surgery compared to on-pump CABG (ONCAB) is that it requires fewer blood product transfusions and has fewer renal, pulmonary, and hematological complications. This case series uniquely discusses two patients who underwent successful beating heart CABG without blood transfusion, followed by RT. |
| format | Article |
| id | doaj-art-d1d6b3d778fa45c4a0c13effca54f643 |
| institution | Kabale University |
| issn | 2297-055X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj-art-d1d6b3d778fa45c4a0c13effca54f6432025-02-07T06:49:47ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-02-011210.3389/fcvm.2025.14867711486771Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survivalÖzge Çetinarslan0Davit Saba1Department of Cardiology, T.C. Demiroglu Science University, Istanbul Florence Nightingale Hospital, Istanbul, TürkiyeDepartment of Cardiovascular Surgery, T.C. Demiroglu Science University, Istanbul Florence Nightingale Hospital, Istanbul, TürkiyePatients with end-stage renal disease face a significantly higher risk of cardiovascular diseases. For patients who are candidates for renal transplantation (RT), major surgeries such as coronary artery bypass grafting (CABG) are associated with cardiac complications as well as higher rates of post-operative complications, including the need for large amounts of blood transfusion, worsening kidney function, infection, and graft rejection. Studies have shown that blood transfusions can increase the risk of graft rejection due to immune system activation. Off-pump CABG (OPCAB), also known as beating heart surgery, is a technique in which a heart–lung machine is not used, and the heart continues to beat throughout the procedure. The main advantage of OPCAB surgery compared to on-pump CABG (ONCAB) is that it requires fewer blood product transfusions and has fewer renal, pulmonary, and hematological complications. This case series uniquely discusses two patients who underwent successful beating heart CABG without blood transfusion, followed by RT.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1486771/fullend-stage renal disease (ESRD)off-pump coronary artery bypass grafting (OPCAB)on-pump coronary artery bypass grafting (ONCAB)renal transplantation (RT)staged surgery vs. combined surgery |
| spellingShingle | Özge Çetinarslan Davit Saba Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survival Frontiers in Cardiovascular Medicine end-stage renal disease (ESRD) off-pump coronary artery bypass grafting (OPCAB) on-pump coronary artery bypass grafting (ONCAB) renal transplantation (RT) staged surgery vs. combined surgery |
| title | Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survival |
| title_full | Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survival |
| title_fullStr | Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survival |
| title_full_unstemmed | Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survival |
| title_short | Case Report: Staged surgical management in ESRD: off-pump CABG followed by renal transplantation to enhance graft survival |
| title_sort | case report staged surgical management in esrd off pump cabg followed by renal transplantation to enhance graft survival |
| topic | end-stage renal disease (ESRD) off-pump coronary artery bypass grafting (OPCAB) on-pump coronary artery bypass grafting (ONCAB) renal transplantation (RT) staged surgery vs. combined surgery |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1486771/full |
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