A Retrospective Analysis of Thymoma: Clinical Radiological Pathological Features and Treatment Modalities – Insights from a Tertiary Care Center

Background and Objectives: Thymoma is the most common tumor found in the anterior mediastinum, but it is still considered a rare neoplasm, with an incidence rate of 0.13–0.26 cases per 100,000 people each year. This study aimed to analyze the clinical, radiological, and pathological characteristics...

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Main Authors: A. Vasudevan, Keerthi Prakash, Ajay Narasimhan, R. Sridhar, R. Narasimhan, C Ganapathy Arumugam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Association of Pulmonologist of Tamil Nadu
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Online Access:https://journals.lww.com/10.4103/japt.japt_25_24
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author A. Vasudevan
Keerthi Prakash
Ajay Narasimhan
R. Sridhar
R. Narasimhan
C Ganapathy Arumugam
author_facet A. Vasudevan
Keerthi Prakash
Ajay Narasimhan
R. Sridhar
R. Narasimhan
C Ganapathy Arumugam
author_sort A. Vasudevan
collection DOAJ
description Background and Objectives: Thymoma is the most common tumor found in the anterior mediastinum, but it is still considered a rare neoplasm, with an incidence rate of 0.13–0.26 cases per 100,000 people each year. This study aimed to analyze the clinical, radiological, and pathological characteristics and treatment modalities of thymoma cases at our institute. Methods: This retrospective observational study was conducted at Apollo Hospital, Chennai, from May 2021 to October 2023. Forty-eight patients with thymoma attended during the above period. Their clinical features, radiological, management, and follow-up, were collected and analyzed. After applying the inclusion and exclusion criteria, 43 patients were included in the study. Results: Thymoma had more incidence in the age group between 30 and 60 years (58.5%). Incidental finding was the most common initial presentation of thymoma in 41.9% of the participants. The majority of participants with paraneoplastic syndromes (71.4%) had myasthenia gravis (MG). Among the 39 operated patients, 3 (7.6%) had robotic surgery, and the recovery (7 days) was faster than conventional surgery. Conclusion: Our study highlights the importance of considering thymoma in patients presenting with anterior mediastinal masses, MG, or incidental findings on imaging. Most thymomas are treatable with minimally invasive techniques, leading to favorable outcomes.
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spelling doaj-art-d2063e5ba35e446a95c5d8171f768d0f2025-02-11T10:15:47ZengWolters Kluwer Medknow PublicationsJournal of Association of Pulmonologist of Tamil Nadu2772-63552772-63632025-01-0181121610.4103/japt.japt_25_24A Retrospective Analysis of Thymoma: Clinical Radiological Pathological Features and Treatment Modalities – Insights from a Tertiary Care CenterA. VasudevanKeerthi PrakashAjay NarasimhanR. SridharR. NarasimhanC Ganapathy ArumugamBackground and Objectives: Thymoma is the most common tumor found in the anterior mediastinum, but it is still considered a rare neoplasm, with an incidence rate of 0.13–0.26 cases per 100,000 people each year. This study aimed to analyze the clinical, radiological, and pathological characteristics and treatment modalities of thymoma cases at our institute. Methods: This retrospective observational study was conducted at Apollo Hospital, Chennai, from May 2021 to October 2023. Forty-eight patients with thymoma attended during the above period. Their clinical features, radiological, management, and follow-up, were collected and analyzed. After applying the inclusion and exclusion criteria, 43 patients were included in the study. Results: Thymoma had more incidence in the age group between 30 and 60 years (58.5%). Incidental finding was the most common initial presentation of thymoma in 41.9% of the participants. The majority of participants with paraneoplastic syndromes (71.4%) had myasthenia gravis (MG). Among the 39 operated patients, 3 (7.6%) had robotic surgery, and the recovery (7 days) was faster than conventional surgery. Conclusion: Our study highlights the importance of considering thymoma in patients presenting with anterior mediastinal masses, MG, or incidental findings on imaging. Most thymomas are treatable with minimally invasive techniques, leading to favorable outcomes.https://journals.lww.com/10.4103/japt.japt_25_24myasthenia gravisparaneoplastic syndromerobotic surgerythymoma
spellingShingle A. Vasudevan
Keerthi Prakash
Ajay Narasimhan
R. Sridhar
R. Narasimhan
C Ganapathy Arumugam
A Retrospective Analysis of Thymoma: Clinical Radiological Pathological Features and Treatment Modalities – Insights from a Tertiary Care Center
Journal of Association of Pulmonologist of Tamil Nadu
myasthenia gravis
paraneoplastic syndrome
robotic surgery
thymoma
title A Retrospective Analysis of Thymoma: Clinical Radiological Pathological Features and Treatment Modalities – Insights from a Tertiary Care Center
title_full A Retrospective Analysis of Thymoma: Clinical Radiological Pathological Features and Treatment Modalities – Insights from a Tertiary Care Center
title_fullStr A Retrospective Analysis of Thymoma: Clinical Radiological Pathological Features and Treatment Modalities – Insights from a Tertiary Care Center
title_full_unstemmed A Retrospective Analysis of Thymoma: Clinical Radiological Pathological Features and Treatment Modalities – Insights from a Tertiary Care Center
title_short A Retrospective Analysis of Thymoma: Clinical Radiological Pathological Features and Treatment Modalities – Insights from a Tertiary Care Center
title_sort retrospective analysis of thymoma clinical radiological pathological features and treatment modalities insights from a tertiary care center
topic myasthenia gravis
paraneoplastic syndrome
robotic surgery
thymoma
url https://journals.lww.com/10.4103/japt.japt_25_24
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