Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence

Abstract Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical metadata can identify multiple disease subtypes w...

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Main Authors: Camran R. Nezhat, Tomiko T. Oskotsky, Joshua F. Robinson, Susan J. Fisher, Angie Tsuei, Binya Liu, Juan C. Irwin, Brice Gaudilliere, Marina Sirota, David K. Stevenson, Linda C. Giudice
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Women's Health
Online Access:https://doi.org/10.1038/s44294-024-00052-w
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author Camran R. Nezhat
Tomiko T. Oskotsky
Joshua F. Robinson
Susan J. Fisher
Angie Tsuei
Binya Liu
Juan C. Irwin
Brice Gaudilliere
Marina Sirota
David K. Stevenson
Linda C. Giudice
author_facet Camran R. Nezhat
Tomiko T. Oskotsky
Joshua F. Robinson
Susan J. Fisher
Angie Tsuei
Binya Liu
Juan C. Irwin
Brice Gaudilliere
Marina Sirota
David K. Stevenson
Linda C. Giudice
author_sort Camran R. Nezhat
collection DOAJ
description Abstract Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical metadata can identify multiple disease subtypes with translation to novel diagnostics and therapeutics. Herein, we present real-world perspectives on endometriosis and the importance of multidisciplinary collaboration in informing molecular, epidemiologic, and cell-specific data in the clinical and surgical contexts.
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institution Kabale University
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publishDate 2025-02-01
publisher Nature Portfolio
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series npj Women's Health
spelling doaj-art-d3ca47c994b94a5597af06cc6d169d6f2025-02-09T13:00:35ZengNature Portfolionpj Women's Health2948-17162025-02-013111610.1038/s44294-024-00052-wReal world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligenceCamran R. Nezhat0Tomiko T. Oskotsky1Joshua F. Robinson2Susan J. Fisher3Angie Tsuei4Binya Liu5Juan C. Irwin6Brice Gaudilliere7Marina Sirota8David K. Stevenson9Linda C. Giudice10Center for Special Minimally Invasive and Robotic Surgery, Camran Nezhat Institute, Stanford University Medical Center, University of California, San FranciscoBakar Computational Health Sciences Institute, University of California San FranciscoCenter for Reproductive Sciences, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San FranciscoCenter for Reproductive Sciences, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San FranciscoCenter for Special Minimally Invasive and Robotic Surgery, Camran Nezhat InstituteDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San FranciscoDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San FranciscoDepartment of Anesthesiology, Pain, and Perioperative Medicine, and (courtesy) Pediatrics, Stanford UniversityBakar Computational Health Sciences Institute, University of California San FranciscoDepartment of Pediatrics, Stanford UniversityDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San FranciscoAbstract Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical metadata can identify multiple disease subtypes with translation to novel diagnostics and therapeutics. Herein, we present real-world perspectives on endometriosis and the importance of multidisciplinary collaboration in informing molecular, epidemiologic, and cell-specific data in the clinical and surgical contexts.https://doi.org/10.1038/s44294-024-00052-w
spellingShingle Camran R. Nezhat
Tomiko T. Oskotsky
Joshua F. Robinson
Susan J. Fisher
Angie Tsuei
Binya Liu
Juan C. Irwin
Brice Gaudilliere
Marina Sirota
David K. Stevenson
Linda C. Giudice
Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence
npj Women's Health
title Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence
title_full Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence
title_fullStr Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence
title_full_unstemmed Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence
title_short Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence
title_sort real world perspectives on endometriosis disease phenotyping through surgery omics health data and artificial intelligence
url https://doi.org/10.1038/s44294-024-00052-w
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