Myeloma cell-derived CXCL7 facilitates proliferation of tumor cells and occurrence of osteolytic lesions through JAK/STAT3 pathway
Abstract Osteolytic lesions and pathological fractures are hallmark manifestations of multiple myeloma (MM), profoundly influencing the quality of life and self-care ability of MM patients. By analyzing transcriptome data and single-cell RNA-seq data from our center and the GEO database, a subset of...
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Main Authors: | Yue Wang, Tianwei Lan, Qiongyan Zhang, Chi Zhou, Peng Liu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2025-02-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-025-07413-6 |
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