Studies of axially chiral atropisomers of an indole-substituted phthalonitrile derivative

A synthesis and theoretical study of 3-(2-methyl-1H-indol-3-yl)-6-nitrophthalonitrile (1) are presented in this study. Structural confirmation of the molecule was achieved using 1H, 13C NMR and mass spectroscopy. The determination of the atropisomer rotational barrier for compound 1 revealed its cla...

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Bibliographic Details
Main Authors: Ayari, Sami, Elleuch, Haitham, Thebti, Amal, Ouzari, Hadda-Imene
Format: Article
Language:English
Published: Académie des sciences 2024-12-01
Series:Comptes Rendus. Chimie
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Online Access:https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.340/
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