Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia
Pertussis, caused primarily by Bordetella pertussis and occasionally by Bordetella parapertussis, remains a major public health issue despite widespread vaccination efforts. Immunocompromised children, such as those with acute lymphoblastic leukemia, are particularly susceptible to vaccine-preventab...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Respiratory Medicine Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007125000097 |
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| author | Diana Marcela Perea Rojas Indiana Luz Rojas Torres Luis Enrique Perea Vásquez |
| author_facet | Diana Marcela Perea Rojas Indiana Luz Rojas Torres Luis Enrique Perea Vásquez |
| author_sort | Diana Marcela Perea Rojas |
| collection | DOAJ |
| description | Pertussis, caused primarily by Bordetella pertussis and occasionally by Bordetella parapertussis, remains a major public health issue despite widespread vaccination efforts. Immunocompromised children, such as those with acute lymphoblastic leukemia, are particularly susceptible to vaccine-preventable diseases, underscoring the importance of ensuring adequate vaccination coverage. We report a case of a 3-year-old boy with ALL who developed a Bordetella parapertussis infection during chemotherapy. The child's lack of documented pertussis vaccination underscores critical gaps in primary healthcare and immunization practices. His case highlights the increased risk of severe infections in unvaccinated, immunocompromised patients and underscores the necessity of maintaining comprehensive vaccination records and robust primary healthcare systems to prevent such infections. The rapid diagnosis and initiation of appropriate antimicrobial therapy, highlights the critical role of early detection and tailored interventions in preventing severe outcomes. |
| format | Article |
| id | doaj-art-dafb8b7e3b934733bd92de96253f4e16 |
| institution | Kabale University |
| issn | 2213-0071 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj-art-dafb8b7e3b934733bd92de96253f4e162025-02-09T05:00:23ZengElsevierRespiratory Medicine Case Reports2213-00712025-01-0153102173Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemiaDiana Marcela Perea Rojas0Indiana Luz Rojas Torres1Luis Enrique Perea Vásquez2Universidad Simón Bolívar, Faculty of Health Sciences, Barranquilla, Colombia; Corresponding author. Universidad Simón Bolívar, Faculty of Health Sciences, Street 59 # 59-95, Barranquilla, 111321, Colombia.Universidad Simón Bolívar, Faculty of Health Sciences, Barranquilla, ColombiaLa Misericordia Clínica Internacional, Quality Department, Barranquilla, ColombiaPertussis, caused primarily by Bordetella pertussis and occasionally by Bordetella parapertussis, remains a major public health issue despite widespread vaccination efforts. Immunocompromised children, such as those with acute lymphoblastic leukemia, are particularly susceptible to vaccine-preventable diseases, underscoring the importance of ensuring adequate vaccination coverage. We report a case of a 3-year-old boy with ALL who developed a Bordetella parapertussis infection during chemotherapy. The child's lack of documented pertussis vaccination underscores critical gaps in primary healthcare and immunization practices. His case highlights the increased risk of severe infections in unvaccinated, immunocompromised patients and underscores the necessity of maintaining comprehensive vaccination records and robust primary healthcare systems to prevent such infections. The rapid diagnosis and initiation of appropriate antimicrobial therapy, highlights the critical role of early detection and tailored interventions in preventing severe outcomes.http://www.sciencedirect.com/science/article/pii/S2213007125000097Whooping coughLeukemiaLymphoidVaccinationPrimary health care |
| spellingShingle | Diana Marcela Perea Rojas Indiana Luz Rojas Torres Luis Enrique Perea Vásquez Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia Respiratory Medicine Case Reports Whooping cough Leukemia Lymphoid Vaccination Primary health care |
| title | Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia |
| title_full | Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia |
| title_fullStr | Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia |
| title_full_unstemmed | Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia |
| title_short | Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia |
| title_sort | addressing the consequences of missing vaccines a case report of pertussis in a child with acute lymphoblastic leukemia |
| topic | Whooping cough Leukemia Lymphoid Vaccination Primary health care |
| url | http://www.sciencedirect.com/science/article/pii/S2213007125000097 |
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