Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report
Cutaneous metastasis (CM) is a rare phenomenon, occurring in only 0.6% to 10.4% of oncology patients. Breast carcinoma represents nearly one-third of all CM cases, although it manifests in a minority of patients with breast cancer (BC). Notably, CMs are detected at the time of primary tumor diagnosi...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-02-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605251314804 |
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| _version_ | 1825206335791169536 |
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| author | Saja Karaja Ahmad Almohamed Ayham Qatza Ahmed Aldolly Sanaa Mansour Alae Aldin Almasri |
| author_facet | Saja Karaja Ahmad Almohamed Ayham Qatza Ahmed Aldolly Sanaa Mansour Alae Aldin Almasri |
| author_sort | Saja Karaja |
| collection | DOAJ |
| description | Cutaneous metastasis (CM) is a rare phenomenon, occurring in only 0.6% to 10.4% of oncology patients. Breast carcinoma represents nearly one-third of all CM cases, although it manifests in a minority of patients with breast cancer (BC). Notably, CMs are detected at the time of primary tumor diagnosis in 6.3% of patients with BC and serve as the initial clinical presentation in only 3.5% of patients. We present a case involving a 53-year-old woman with a 5-month history of asymptomatic infiltrating nodules in the axillae and trunk. Skin biopsy and immunohistochemical analysis confirmed metastatic breast carcinoma with positive estrogen receptor staining. This case underscores the importance of early detection and precise diagnostic techniques in managing metastatic adenocarcinoma with cutaneous manifestations. Despite the promising outcome of the initial treatment, the disease progression in this case highlights the aggressive nature of CMs and the ongoing need for research and advanced therapeutic strategies. |
| format | Article |
| id | doaj-art-dca4bc8a249d4e8a8a2bdccabd936eae |
| institution | Kabale University |
| issn | 1473-2300 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj-art-dca4bc8a249d4e8a8a2bdccabd936eae2025-02-07T11:03:29ZengSAGE PublishingJournal of International Medical Research1473-23002025-02-015310.1177/03000605251314804Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case reportSaja KarajaAhmad AlmohamedAyham QatzaAhmed AldollySanaa MansourAlae Aldin AlmasriCutaneous metastasis (CM) is a rare phenomenon, occurring in only 0.6% to 10.4% of oncology patients. Breast carcinoma represents nearly one-third of all CM cases, although it manifests in a minority of patients with breast cancer (BC). Notably, CMs are detected at the time of primary tumor diagnosis in 6.3% of patients with BC and serve as the initial clinical presentation in only 3.5% of patients. We present a case involving a 53-year-old woman with a 5-month history of asymptomatic infiltrating nodules in the axillae and trunk. Skin biopsy and immunohistochemical analysis confirmed metastatic breast carcinoma with positive estrogen receptor staining. This case underscores the importance of early detection and precise diagnostic techniques in managing metastatic adenocarcinoma with cutaneous manifestations. Despite the promising outcome of the initial treatment, the disease progression in this case highlights the aggressive nature of CMs and the ongoing need for research and advanced therapeutic strategies.https://doi.org/10.1177/03000605251314804 |
| spellingShingle | Saja Karaja Ahmad Almohamed Ayham Qatza Ahmed Aldolly Sanaa Mansour Alae Aldin Almasri Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report Journal of International Medical Research |
| title | Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report |
| title_full | Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report |
| title_fullStr | Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report |
| title_full_unstemmed | Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report |
| title_short | Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report |
| title_sort | cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation a case report |
| url | https://doi.org/10.1177/03000605251314804 |
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