Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin
An ultrasensitive and selective voltammetric platform combined a molecularly imprinted poly(pyrrole) membrane with Ag-nanoparticle-functionalized black phosphorus nanosheets (MIP/BPNS-AgNPs) was developed for trace GAT detection. The physicochemical properties of the MIP/BPNS-AgNPs were studied by v...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Food Chemistry: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157524009829 |
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| author | Jingtao Wu Yonghui Xia Tianyu Wang Yafeng Zhang Guangli Li |
| author_facet | Jingtao Wu Yonghui Xia Tianyu Wang Yafeng Zhang Guangli Li |
| author_sort | Jingtao Wu |
| collection | DOAJ |
| description | An ultrasensitive and selective voltammetric platform combined a molecularly imprinted poly(pyrrole) membrane with Ag-nanoparticle-functionalized black phosphorus nanosheets (MIP/BPNS-AgNPs) was developed for trace GAT detection. The physicochemical properties of the MIP/BPNS-AgNPs were studied by various spectroscopic and electrochemical techniques. BPNS-AgNPs improved the ambient stability and electrochemical activity of the BPNS and possessed a large surface area for accommodating abundant templates to produce specific imprinted sites. The resulting MIP/BPNS-AgNP-modified glassy carbon electrode (GCE) greatly enhanced voltammetric responses for GAT. The MIP/BPNS-AgNP/GCE exhibited admirable GAT determination performance, with two linear responses (0.001–1 and 1–50 μM), high sensitivity (9.965 and 0.5378 μA μM−1), and a low detection limit of 0.2 nM. In addition, the MIP electrode could selectively detect GAT in complex matrices and retain roust responses for a month. The applicability of MIP/BPNS-AgNP/GCE toward the detection of GAT in pharmaceutical formulations, milk, and human serum was verified with satisfactory results. |
| format | Article |
| id | doaj-art-dd50bfa728aa475f9400c1e699c9dbf2 |
| institution | Kabale University |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-dd50bfa728aa475f9400c1e699c9dbf22025-02-12T05:31:56ZengElsevierFood Chemistry: X2590-15752025-01-0125102094Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of GatifloxacinJingtao Wu0Yonghui Xia1Tianyu Wang2Yafeng Zhang3Guangli Li4Hunan Key Laboratory of Biomedical Nanomaterials and Devices, College of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, ChinaZhuzhou Institute for Food and Drug Control, Zhuzhou 412000, ChinaHunan Key Laboratory of Biomedical Nanomaterials and Devices, College of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, ChinaHunan Key Laboratory of Biomedical Nanomaterials and Devices, College of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, ChinaHunan Key Laboratory of Biomedical Nanomaterials and Devices, College of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China; Corresponding author.An ultrasensitive and selective voltammetric platform combined a molecularly imprinted poly(pyrrole) membrane with Ag-nanoparticle-functionalized black phosphorus nanosheets (MIP/BPNS-AgNPs) was developed for trace GAT detection. The physicochemical properties of the MIP/BPNS-AgNPs were studied by various spectroscopic and electrochemical techniques. BPNS-AgNPs improved the ambient stability and electrochemical activity of the BPNS and possessed a large surface area for accommodating abundant templates to produce specific imprinted sites. The resulting MIP/BPNS-AgNP-modified glassy carbon electrode (GCE) greatly enhanced voltammetric responses for GAT. The MIP/BPNS-AgNP/GCE exhibited admirable GAT determination performance, with two linear responses (0.001–1 and 1–50 μM), high sensitivity (9.965 and 0.5378 μA μM−1), and a low detection limit of 0.2 nM. In addition, the MIP electrode could selectively detect GAT in complex matrices and retain roust responses for a month. The applicability of MIP/BPNS-AgNP/GCE toward the detection of GAT in pharmaceutical formulations, milk, and human serum was verified with satisfactory results.http://www.sciencedirect.com/science/article/pii/S2590157524009829Molecularly imprinted polymerPoly(pyrrole)Ag nanoparticlesBlack phosphorus nanosheetsGatifloxacin determination |
| spellingShingle | Jingtao Wu Yonghui Xia Tianyu Wang Yafeng Zhang Guangli Li Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin Food Chemistry: X Molecularly imprinted polymer Poly(pyrrole) Ag nanoparticles Black phosphorus nanosheets Gatifloxacin determination |
| title | Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin |
| title_full | Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin |
| title_fullStr | Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin |
| title_full_unstemmed | Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin |
| title_short | Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin |
| title_sort | efficient voltammetric platform combining a molecularly imprinted polymer and silver nanoparticle decorated black phosphorus nanosheets for selective determination of gatifloxacin |
| topic | Molecularly imprinted polymer Poly(pyrrole) Ag nanoparticles Black phosphorus nanosheets Gatifloxacin determination |
| url | http://www.sciencedirect.com/science/article/pii/S2590157524009829 |
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