Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women

Abstract Several studies report an impact of the neurotransmitter dopamine (DA) on human immune cells, with effects dependent on the immune cell type addressed and their activation status. Another contributing factor appears to be sex, as sex-specific differences in the dopaminergic pathway are desc...

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Bibliographic Details
Main Authors: Leonie Fleige, Silvia Capellino
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Biology of Sex Differences
Subjects:
Online Access:https://doi.org/10.1186/s13293-025-00689-5
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