Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.

Background and objectives: The steroidal and Non-Steroidal Anti-Inflammatory drugs (NSAIDs) are widely used classes of medications for their anti-Inflammatory and analgesic effects and are associated with the risk of many oral side effects and which might be presented with variable degrees of sever...

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Main Authors: Shayma Ghazi, Khalid Yasin Rasul, Aras Khidhir Hamad, Aso Abdulkhaliq Khidhir, Lozan Khalil Ahmed
Format: Article
Language:English
Published: College Of Dentistry Hawler Medical University 2024-03-01
Series:Erbil Dental Journal
Subjects:
Online Access:https://edj.hmu.edu.krd/index.php/journal/article/view/254
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author Shayma Ghazi
Khalid Yasin Rasul
Aras Khidhir Hamad
Aso Abdulkhaliq Khidhir
Lozan Khalil Ahmed
author_facet Shayma Ghazi
Khalid Yasin Rasul
Aras Khidhir Hamad
Aso Abdulkhaliq Khidhir
Lozan Khalil Ahmed
author_sort Shayma Ghazi
collection DOAJ
description Background and objectives: The steroidal and Non-Steroidal Anti-Inflammatory drugs (NSAIDs) are widely used classes of medications for their anti-Inflammatory and analgesic effects and are associated with the risk of many oral side effects and which might be presented with variable degrees of severity. The main objective of this research was to identify oral side effects that could be associated with using Steroidal or NSAIDs. Patients and Methods: A total number of 82 patients who were attending the teaching clinics at the college of dentistry and were using steroids or NSAIDs participated in this study and they were interviewed and examined clinically for the presence of any abnormal oral presentation. The data were all recorded on a pre-designed questionnaire. The data was expressed as         percentage and analyzed statistically using ANOVA and t-test. Results: The data showed that a majority of NSAIDs users complained of gingival bleeding (39%) and Xerostomia (32%), while corticosteroid users complained of fungal infection (50%), gingival inflammation (25%) and other less frequent side effects. Drugs that were associated with the most oral side effects were aspirin, ibuprofen, mefenamic acid and prednisolone. Conclusion: Data analysis showed that many oral side effects might be related to steroidal and NSAIDs. It is important to consider that drugs in general may cause oral side effects at different doses, dosage forms and durations of use and may have a variety of clinical presentation. The dentists have a crucial role in identifying these drug-related oral side effects through their clinical practices in order to provide the proper management for the patients.
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spelling doaj-art-e4ebb87336db4e13a58f322c3d2c902c2025-02-10T20:48:03ZengCollege Of Dentistry Hawler Medical UniversityErbil Dental Journal2523-61722616-47952024-03-0163Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.Shayma Ghazi0Khalid Yasin Rasul1Aras Khidhir Hamad2Aso Abdulkhaliq Khidhir3Lozan Khalil Ahmed4Lecturer at the College of Dentistry, Hawler Medical University.Undergraduate Student at the College of Dentistry, Hawler Medical University.Undergraduate Student at the College of Dentistry, Hawler Medical University.Undergraduate Student at the College of Dentistry, Hawler Medical University.Undergraduate Student at the College of Dentistry, Hawler Medical University. Background and objectives: The steroidal and Non-Steroidal Anti-Inflammatory drugs (NSAIDs) are widely used classes of medications for their anti-Inflammatory and analgesic effects and are associated with the risk of many oral side effects and which might be presented with variable degrees of severity. The main objective of this research was to identify oral side effects that could be associated with using Steroidal or NSAIDs. Patients and Methods: A total number of 82 patients who were attending the teaching clinics at the college of dentistry and were using steroids or NSAIDs participated in this study and they were interviewed and examined clinically for the presence of any abnormal oral presentation. The data were all recorded on a pre-designed questionnaire. The data was expressed as         percentage and analyzed statistically using ANOVA and t-test. Results: The data showed that a majority of NSAIDs users complained of gingival bleeding (39%) and Xerostomia (32%), while corticosteroid users complained of fungal infection (50%), gingival inflammation (25%) and other less frequent side effects. Drugs that were associated with the most oral side effects were aspirin, ibuprofen, mefenamic acid and prednisolone. Conclusion: Data analysis showed that many oral side effects might be related to steroidal and NSAIDs. It is important to consider that drugs in general may cause oral side effects at different doses, dosage forms and durations of use and may have a variety of clinical presentation. The dentists have a crucial role in identifying these drug-related oral side effects through their clinical practices in order to provide the proper management for the patients. https://edj.hmu.edu.krd/index.php/journal/article/view/254Side effectssteroidsNSAIDsxerostomiaUlcers
spellingShingle Shayma Ghazi
Khalid Yasin Rasul
Aras Khidhir Hamad
Aso Abdulkhaliq Khidhir
Lozan Khalil Ahmed
Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.
Erbil Dental Journal
Side effects
steroids
NSAIDs
xerostomia
Ulcers
title Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.
title_full Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.
title_fullStr Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.
title_full_unstemmed Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.
title_short Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.
title_sort side effects of steroidal and non steroidal anti inflammatory drugs on the oral cavity
topic Side effects
steroids
NSAIDs
xerostomia
Ulcers
url https://edj.hmu.edu.krd/index.php/journal/article/view/254
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AT asoabdulkhaliqkhidhir sideeffectsofsteroidalandnonsteroidalantiinflammatorydrugsontheoralcavity
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