Association of lung health and cardiovascular health (Life’s Essential 8)
BackgroundCardiorespiratory health issues often intersect. This study explored the relationship between lung health and the recently updated Cardiovascular Health Measure (Life’s Essential 8).MethodsData from the 2007–2018 National Health and Nutrition Examination Survey (NHANES) were analyzed. Thre...
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Frontiers Media S.A.
2025-02-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1481213/full |
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| author | Wanjia Zhang Menglong Zou Junyao Liang Dexu Zhang Man Zhou Hui Feng Chusen Tang Jie Xiao Zhan Yi Yin Xu |
| author_facet | Wanjia Zhang Menglong Zou Junyao Liang Dexu Zhang Man Zhou Hui Feng Chusen Tang Jie Xiao Zhan Yi Yin Xu |
| author_sort | Wanjia Zhang |
| collection | DOAJ |
| description | BackgroundCardiorespiratory health issues often intersect. This study explored the relationship between lung health and the recently updated Cardiovascular Health Measure (Life’s Essential 8).MethodsData from the 2007–2018 National Health and Nutrition Examination Survey (NHANES) were analyzed. Three cohorts were included: lung disease in the Main cohort (N = 9,772), lung function in the Spirometry sub-cohort (N = 3,896), and respiratory symptoms in the Respiratory Symptoms sub-cohort (Age > 40) (N = 3,449). LE8 scores were used as both continuous and categorical variables (0–49, 50–79, 80–100). Weighted multivariate regression analyses examined the correlations between LE8 and lung health, and weighted restricted cubic spline (RCS) regression analyzed potential non-linear relationships. Subgroup analysis was conducted to verify stability.ResultsOverall lung health was better in the high LE8 group than in the low LE8 group. In the fully adjusted model, the high LE8 group had significantly lower odds of asthma (OR = 0.42; 95% CI = 0.29, 0.59) and chronic bronchitis (OR = 0.27; 95% CI = 0.15, 0.49) compared to the low LE8 group. Regarding lung function, each 10-point increase in LE8 was associated with an increase of 50 ml in FEV1 (Beta = 50; 95% CI = 32, 67) and 56 ml in FVC (Beta = 56; 95% CI = 32, 79). Among middle-aged and older adults (age > 40), the high LE8 group had significantly lower odds of respiratory symptoms, including cough (OR = 0.23; 95% CI = 0.12, 0.46), phlegm (OR = 0.42; 95% CI = 0.19, 0.90), and wheezing (OR = 0.29; 95% CI = 0.15, 0.54). RCS analyses demonstrated a non-linear negative correlation between LE8 and cough, sputum, and wheeze. Subgroup and sensitivity analysis suggested stability.ConclusionLife’s Essential 8 (LE8) scores are positively associated with lung health in the US population. These findings provide a valuable reference for maintaining overall cardiorespiratory health. |
| format | Article |
| id | doaj-art-e66e42e69a624573bc9230345e81a65a |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-02-01 |
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| series | Frontiers in Medicine |
| spelling | doaj-art-e66e42e69a624573bc9230345e81a65a2025-02-07T15:15:03ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-02-011210.3389/fmed.2025.14812131481213Association of lung health and cardiovascular health (Life’s Essential 8)Wanjia Zhang0Menglong Zou1Junyao Liang2Dexu Zhang3Man Zhou4Hui Feng5Chusen Tang6Jie Xiao7Zhan Yi8Yin Xu9The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaHunan University of Chinese Medicine, Changsha, Hunan, ChinaThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, ChinaBackgroundCardiorespiratory health issues often intersect. This study explored the relationship between lung health and the recently updated Cardiovascular Health Measure (Life’s Essential 8).MethodsData from the 2007–2018 National Health and Nutrition Examination Survey (NHANES) were analyzed. Three cohorts were included: lung disease in the Main cohort (N = 9,772), lung function in the Spirometry sub-cohort (N = 3,896), and respiratory symptoms in the Respiratory Symptoms sub-cohort (Age > 40) (N = 3,449). LE8 scores were used as both continuous and categorical variables (0–49, 50–79, 80–100). Weighted multivariate regression analyses examined the correlations between LE8 and lung health, and weighted restricted cubic spline (RCS) regression analyzed potential non-linear relationships. Subgroup analysis was conducted to verify stability.ResultsOverall lung health was better in the high LE8 group than in the low LE8 group. In the fully adjusted model, the high LE8 group had significantly lower odds of asthma (OR = 0.42; 95% CI = 0.29, 0.59) and chronic bronchitis (OR = 0.27; 95% CI = 0.15, 0.49) compared to the low LE8 group. Regarding lung function, each 10-point increase in LE8 was associated with an increase of 50 ml in FEV1 (Beta = 50; 95% CI = 32, 67) and 56 ml in FVC (Beta = 56; 95% CI = 32, 79). Among middle-aged and older adults (age > 40), the high LE8 group had significantly lower odds of respiratory symptoms, including cough (OR = 0.23; 95% CI = 0.12, 0.46), phlegm (OR = 0.42; 95% CI = 0.19, 0.90), and wheezing (OR = 0.29; 95% CI = 0.15, 0.54). RCS analyses demonstrated a non-linear negative correlation between LE8 and cough, sputum, and wheeze. Subgroup and sensitivity analysis suggested stability.ConclusionLife’s Essential 8 (LE8) scores are positively associated with lung health in the US population. These findings provide a valuable reference for maintaining overall cardiorespiratory health.https://www.frontiersin.org/articles/10.3389/fmed.2025.1481213/fullcardiovascular healthlung healthLife’s Essential 8NHANEScross-sectional study |
| spellingShingle | Wanjia Zhang Menglong Zou Junyao Liang Dexu Zhang Man Zhou Hui Feng Chusen Tang Jie Xiao Zhan Yi Yin Xu Association of lung health and cardiovascular health (Life’s Essential 8) Frontiers in Medicine cardiovascular health lung health Life’s Essential 8 NHANES cross-sectional study |
| title | Association of lung health and cardiovascular health (Life’s Essential 8) |
| title_full | Association of lung health and cardiovascular health (Life’s Essential 8) |
| title_fullStr | Association of lung health and cardiovascular health (Life’s Essential 8) |
| title_full_unstemmed | Association of lung health and cardiovascular health (Life’s Essential 8) |
| title_short | Association of lung health and cardiovascular health (Life’s Essential 8) |
| title_sort | association of lung health and cardiovascular health life s essential 8 |
| topic | cardiovascular health lung health Life’s Essential 8 NHANES cross-sectional study |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1481213/full |
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