Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative Study
**Background:** Overactive bladder (OAB) is a symptom-defined disorder. A range of instruments are available for assessing OAB symptom bother, urinary urgency and the effects of symptoms on health-related quality of life (HRQoL), but few have been specifically designed and validated for this conditi...
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| Format: | Article |
| Language: | English |
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Columbia Data Analytics, LLC
2016-08-01
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| Series: | Journal of Health Economics and Outcomes Research |
| Online Access: | https://doi.org/10.36469/9816 |
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| author | Natalia Hawken Zalmai Hakimi Samuel Aballéa Jameel Nazir Isaac A. O. Odeyemi Mondher Toumi |
| author_facet | Natalia Hawken Zalmai Hakimi Samuel Aballéa Jameel Nazir Isaac A. O. Odeyemi Mondher Toumi |
| author_sort | Natalia Hawken |
| collection | DOAJ |
| description | **Background:** Overactive bladder (OAB) is a symptom-defined disorder. A range of instruments are available for assessing OAB symptom bother, urinary urgency and the effects of symptoms on health-related quality of life (HRQoL), but few have been specifically designed and validated for this condition. HRQoL instruments should capture the concepts that are most relevant to patients. To our knowledge, there is no existing published conceptual framework for OAB.
**Objectives:** We performed a qualitative study to explore the impact of symptoms of OAB on affected patients and to develop a conceptual framework for OAB.
**Methods:** Patients diagnosed with OAB living in the United Kingdom were interviewed on the telephone by a trained psychologist using an interview discussion guide. Interview transcripts were analyzed thematically by two psychologists. Data collection and analysis was completed when data saturation, i.e. when little or no new information was obtained, was achieved.
**Results:** A total of 30 patients were interviewed. Fifteen patients (50%) had urge incontinence (i.e. OAB-wet). Interview data showed that OAB affected role functioning, sleep quality, social functioning, and emotional/mental functioning. In addition, patients often adopted non-medical coping strategies to manage their symptoms (e.g. planning activities). Factors which affected more than 50% of patients were going for a short walk, waking up at night, travelling/holidays, socializing/going out, embarrassment/shame, need to plan activities, and restriction of places visited. More patients with OAB-wet reported impairment of social and emotional/mental functioning than patients with OAB-dry. A conceptual framework for adults with OAB depicting the relationships between OAB concepts (or outcomes) was developed.
**Conclusions:** OAB has a profound effect on patient HRQoL and negatively affects a broad range of functions, including daily and work activities, leisure and social activities, psychological well-being, and sleep capacity. The conceptual framework emerging from this study supports the utilization of existing disease-specific HRQoL instruments, but identifies that work-related effects, which are relevant for OAB patients, are missing from currently available measures. |
| format | Article |
| id | doaj-art-e7cb78ad91e044a8ae3d24984955894c |
| institution | Kabale University |
| issn | 2327-2236 |
| language | English |
| publishDate | 2016-08-01 |
| publisher | Columbia Data Analytics, LLC |
| record_format | Article |
| series | Journal of Health Economics and Outcomes Research |
| spelling | doaj-art-e7cb78ad91e044a8ae3d24984955894c2025-02-10T16:12:30ZengColumbia Data Analytics, LLCJournal of Health Economics and Outcomes Research2327-22362016-08-0142Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative StudyNatalia HawkenZalmai HakimiSamuel AballéaJameel NazirIsaac A. O. OdeyemiMondher Toumi**Background:** Overactive bladder (OAB) is a symptom-defined disorder. A range of instruments are available for assessing OAB symptom bother, urinary urgency and the effects of symptoms on health-related quality of life (HRQoL), but few have been specifically designed and validated for this condition. HRQoL instruments should capture the concepts that are most relevant to patients. To our knowledge, there is no existing published conceptual framework for OAB. **Objectives:** We performed a qualitative study to explore the impact of symptoms of OAB on affected patients and to develop a conceptual framework for OAB. **Methods:** Patients diagnosed with OAB living in the United Kingdom were interviewed on the telephone by a trained psychologist using an interview discussion guide. Interview transcripts were analyzed thematically by two psychologists. Data collection and analysis was completed when data saturation, i.e. when little or no new information was obtained, was achieved. **Results:** A total of 30 patients were interviewed. Fifteen patients (50%) had urge incontinence (i.e. OAB-wet). Interview data showed that OAB affected role functioning, sleep quality, social functioning, and emotional/mental functioning. In addition, patients often adopted non-medical coping strategies to manage their symptoms (e.g. planning activities). Factors which affected more than 50% of patients were going for a short walk, waking up at night, travelling/holidays, socializing/going out, embarrassment/shame, need to plan activities, and restriction of places visited. More patients with OAB-wet reported impairment of social and emotional/mental functioning than patients with OAB-dry. A conceptual framework for adults with OAB depicting the relationships between OAB concepts (or outcomes) was developed. **Conclusions:** OAB has a profound effect on patient HRQoL and negatively affects a broad range of functions, including daily and work activities, leisure and social activities, psychological well-being, and sleep capacity. The conceptual framework emerging from this study supports the utilization of existing disease-specific HRQoL instruments, but identifies that work-related effects, which are relevant for OAB patients, are missing from currently available measures.https://doi.org/10.36469/9816 |
| spellingShingle | Natalia Hawken Zalmai Hakimi Samuel Aballéa Jameel Nazir Isaac A. O. Odeyemi Mondher Toumi Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative Study Journal of Health Economics and Outcomes Research |
| title | Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative Study |
| title_full | Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative Study |
| title_fullStr | Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative Study |
| title_full_unstemmed | Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative Study |
| title_short | Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative Study |
| title_sort | elicitation of health related quality of life concepts associated with overactive bladder a qualitative study |
| url | https://doi.org/10.36469/9816 |
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