Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources

Whey proteins, the most abundant proteins in human milk (HM), play a vital role in the growth and development of infants. This review first elaborates on the main components of HM whey proteins, including various proteins with specific functions, and details the functions of these proteins in terms...

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Main Authors: Xing Li, Xiaomei Zhang, Minghui Zhang, Xiaojia Liu, Ziyue Gao, Junying Zhao, Weicang Qiao, Lijun Chen
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Food Chemistry: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590157524009702
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author Xing Li
Xiaomei Zhang
Minghui Zhang
Xiaojia Liu
Ziyue Gao
Junying Zhao
Weicang Qiao
Lijun Chen
author_facet Xing Li
Xiaomei Zhang
Minghui Zhang
Xiaojia Liu
Ziyue Gao
Junying Zhao
Weicang Qiao
Lijun Chen
author_sort Xing Li
collection DOAJ
description Whey proteins, the most abundant proteins in human milk (HM), play a vital role in the growth and development of infants. This review first elaborates on the main components of HM whey proteins, including various proteins with specific functions, and details the functions of these proteins in terms of infant nutrition, immunity, as well as growth and development. Secondly, it analyzes factors that affect HM whey proteins, such as maternal differences, dietary habits, and geographical differences. Thirdly, it discusses detection methods for HM whey proteins, covering the principles, advantages, and limitations of different technical means. Finally, it compares whey proteins from different milk sources, highlighting their differences in composition, function, and characteristics. This review aims to comprehensively present the current research status of HM whey protein, provide a scientific basis for maternal and infant health, and contribute to optimizing infant feeding strategies and the research and development of related products.
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institution Kabale University
issn 2590-1575
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Food Chemistry: X
spelling doaj-art-eb9cbd0443964de28572638150f3567f2025-02-12T05:31:53ZengElsevierFood Chemistry: X2590-15752025-01-0125102082Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sourcesXing Li0Xiaomei Zhang1Minghui Zhang2Xiaojia Liu3Ziyue Gao4Junying Zhao5Weicang Qiao6Lijun Chen7Key Laboratory of Dairy Science, Ministry of Education, Food Science College, Northeast Agricultural University, Harbin, 150030, China; National Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, ChinaNational Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, ChinaNational Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, ChinaKey Laboratory of Dairy Science, Ministry of Education, Food Science College, Northeast Agricultural University, Harbin, 150030, China; National Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, ChinaKey Laboratory of Dairy Science, Ministry of Education, Food Science College, Northeast Agricultural University, Harbin, 150030, China; National Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, ChinaNational Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, ChinaNational Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, ChinaKey Laboratory of Dairy Science, Ministry of Education, Food Science College, Northeast Agricultural University, Harbin, 150030, China; National Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China; Corresponding author at: Beijing Sanyuan Foods Co., Ltd., No. 8, Yingchang Street 100076, Yinghai Town, Daxing District, Beijing, China.Whey proteins, the most abundant proteins in human milk (HM), play a vital role in the growth and development of infants. This review first elaborates on the main components of HM whey proteins, including various proteins with specific functions, and details the functions of these proteins in terms of infant nutrition, immunity, as well as growth and development. Secondly, it analyzes factors that affect HM whey proteins, such as maternal differences, dietary habits, and geographical differences. Thirdly, it discusses detection methods for HM whey proteins, covering the principles, advantages, and limitations of different technical means. Finally, it compares whey proteins from different milk sources, highlighting their differences in composition, function, and characteristics. This review aims to comprehensively present the current research status of HM whey protein, provide a scientific basis for maternal and infant health, and contribute to optimizing infant feeding strategies and the research and development of related products.http://www.sciencedirect.com/science/article/pii/S2590157524009702Whey proteinHuman milkBioactive componentMaternal factorsDifferent milk sourcesProteomic analysis
spellingShingle Xing Li
Xiaomei Zhang
Minghui Zhang
Xiaojia Liu
Ziyue Gao
Junying Zhao
Weicang Qiao
Lijun Chen
Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources
Food Chemistry: X
Whey protein
Human milk
Bioactive component
Maternal factors
Different milk sources
Proteomic analysis
title Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources
title_full Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources
title_fullStr Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources
title_full_unstemmed Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources
title_short Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources
title_sort human milk whey proteins constituents influencing factors detection methods and comparative analysis with other sources
topic Whey protein
Human milk
Bioactive component
Maternal factors
Different milk sources
Proteomic analysis
url http://www.sciencedirect.com/science/article/pii/S2590157524009702
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