Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus
Enteromorpha prolifera polysaccharide (EPP) is a kind of seaweed polysaccharide with outstanding biological activity. In this study, a 49-day culture trial was conducted to explore the effects of dietary EPP on intestinal health in spotted sea bass. Six experimental diets containing 0, 3, 6, 9, 12,...
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Elsevier
2025-03-01
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| Series: | Aquaculture Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352513424006720 |
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| author | Zhongying Long Longhui Liu Huihui Qin Sishun Zhou Lumin Kong Jianrong Ma Hao Lin Zhangfan Huang Yi Lin Zhongbao Li |
| author_facet | Zhongying Long Longhui Liu Huihui Qin Sishun Zhou Lumin Kong Jianrong Ma Hao Lin Zhangfan Huang Yi Lin Zhongbao Li |
| author_sort | Zhongying Long |
| collection | DOAJ |
| description | Enteromorpha prolifera polysaccharide (EPP) is a kind of seaweed polysaccharide with outstanding biological activity. In this study, a 49-day culture trial was conducted to explore the effects of dietary EPP on intestinal health in spotted sea bass. Six experimental diets containing 0, 3, 6, 9, 12, and 15 g/kg EPP were formulated. A total of 540 similarly sized and healthy spotted sea bass were randomly assigned to 6 groups and fed the respective diet. The results showed that dietary EPP supplementation significantly improved the activity of digestive enzymes, including amylase, lipase, and trypsin, and reduced the permeability of the intestinal mucosa, which was shown to significantly reduce the content of D-lactic acid and the activity of diamine oxidase in serum. On the other hand, intestinal villi length and muscle thickness increased significantly, and intestinal tissue morphology improved. Dietary EPP also changed intestinal microbial composition, increased Firmicutes abundance, and increased intestinal microbial diversity. Transcriptome results suggest that EPP may improve intestinal tissue morphology and intestinal barrier function by up-regulating tight junction protein 1 (TJP1) and zona occludens 1 (ZO-1) genes, thereby improving intestinal health. In addition, significant changes in several inflammatory factor genes were observed. EPP may have enormous potential for regulating immune and inflammatory responses. In conclusion, dietary EPP can significantly improve the intestinal health of spotted sea bass. |
| format | Article |
| id | doaj-art-ed6e4630a1c54eeab344d65d081ddd20 |
| institution | Kabale University |
| issn | 2352-5134 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Aquaculture Reports |
| spelling | doaj-art-ed6e4630a1c54eeab344d65d081ddd202025-02-06T05:12:13ZengElsevierAquaculture Reports2352-51342025-03-0140102584Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatusZhongying Long0Longhui Liu1Huihui Qin2Sishun Zhou3Lumin Kong4Jianrong Ma5Hao Lin6Zhangfan Huang7Yi Lin8Zhongbao Li9Fisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, ChinaFisheries College, Jimei University, Xiamen, China; Fujian Provincial Key Laboratory of Marine Fishery Resources and Eco-environment, Xiamen, China; Correspondence to: Fisheries College, Jimei University, Xiamen, Fujian, China.Enteromorpha prolifera polysaccharide (EPP) is a kind of seaweed polysaccharide with outstanding biological activity. In this study, a 49-day culture trial was conducted to explore the effects of dietary EPP on intestinal health in spotted sea bass. Six experimental diets containing 0, 3, 6, 9, 12, and 15 g/kg EPP were formulated. A total of 540 similarly sized and healthy spotted sea bass were randomly assigned to 6 groups and fed the respective diet. The results showed that dietary EPP supplementation significantly improved the activity of digestive enzymes, including amylase, lipase, and trypsin, and reduced the permeability of the intestinal mucosa, which was shown to significantly reduce the content of D-lactic acid and the activity of diamine oxidase in serum. On the other hand, intestinal villi length and muscle thickness increased significantly, and intestinal tissue morphology improved. Dietary EPP also changed intestinal microbial composition, increased Firmicutes abundance, and increased intestinal microbial diversity. Transcriptome results suggest that EPP may improve intestinal tissue morphology and intestinal barrier function by up-regulating tight junction protein 1 (TJP1) and zona occludens 1 (ZO-1) genes, thereby improving intestinal health. In addition, significant changes in several inflammatory factor genes were observed. EPP may have enormous potential for regulating immune and inflammatory responses. In conclusion, dietary EPP can significantly improve the intestinal health of spotted sea bass.http://www.sciencedirect.com/science/article/pii/S2352513424006720Enteromorpha prolifera polysaccharideSpotted sea bassIntestinal healthTranscriptomeIntestinal microbial |
| spellingShingle | Zhongying Long Longhui Liu Huihui Qin Sishun Zhou Lumin Kong Jianrong Ma Hao Lin Zhangfan Huang Yi Lin Zhongbao Li Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus Aquaculture Reports Enteromorpha prolifera polysaccharide Spotted sea bass Intestinal health Transcriptome Intestinal microbial |
| title | Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus |
| title_full | Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus |
| title_fullStr | Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus |
| title_full_unstemmed | Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus |
| title_short | Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus |
| title_sort | effects of enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass lateolabrax maculatus |
| topic | Enteromorpha prolifera polysaccharide Spotted sea bass Intestinal health Transcriptome Intestinal microbial |
| url | http://www.sciencedirect.com/science/article/pii/S2352513424006720 |
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