GLP-1 Receptor Agonists’ Impact on Fertility - A Review
Purpose of Research: The aim of the research is to summarize the impact of GLP-1 analogs on fertility according to clinical studies, particularly in obese or overweight women with PCOS. Research Materials and Methods: The study is built upon an analysis of current literature, clinical trials, me...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nicolaus Copernicus University in Toruń
2025-02-01
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| Series: | Quality in Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/QS/article/view/58325 |
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| Summary: | Purpose of Research: The aim of the research is to summarize the impact of GLP-1 analogs on fertility according to clinical studies, particularly in obese or overweight women with PCOS.
Research Materials and Methods: The study is built upon an analysis of current literature, clinical trials, meta-analyses, and systematic reviews as well as press reports from various sources. Data were collected from studies examining the effects of obesity on fertility, as well as the impact of GLP-1 analogs on both fertility and obesity.
Basic Results: GLP-1 analogs promote weight management among obese and overweight patients leading to improvement in their fertility. Furthermore, they improve pregnancy rates in women with PCOS, although further examination is needed.
Conclusions: We observe, GLP-1 analogs are often used in regulation of type 2 diabetes. They have proven their ability to impact a variety of hormonal as well as metabolic pathways. They manage glucose metabolism, appetite, as well as insulin secretion. Alongside their metabolic influence, research demonstrates that GLP-1 analogs may have an effect on the reproductive system, involving fertility via metabolic and hormonal pathways.
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| ISSN: | 2450-3118 |