GLP-1 Receptor Agonists’ Impact on Fertility - A Review
Purpose of Research: The aim of the research is to summarize the impact of GLP-1 analogs on fertility according to clinical studies, particularly in obese or overweight women with PCOS. Research Materials and Methods: The study is built upon an analysis of current literature, clinical trials, me...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-02-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/58325 |
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| author | Joanna Wojda Katarzyna Lesiczka-Fedoryj Anna Walczak Zuzanna Kościuszko Adam Sobiński Matylda Czerwonka Katarzyna Kurza Julianna Podolec Silvia Ciraolo Agnieszka Kulczycka-Rowicka |
| author_facet | Joanna Wojda Katarzyna Lesiczka-Fedoryj Anna Walczak Zuzanna Kościuszko Adam Sobiński Matylda Czerwonka Katarzyna Kurza Julianna Podolec Silvia Ciraolo Agnieszka Kulczycka-Rowicka |
| author_sort | Joanna Wojda |
| collection | DOAJ |
| description |
Purpose of Research: The aim of the research is to summarize the impact of GLP-1 analogs on fertility according to clinical studies, particularly in obese or overweight women with PCOS.
Research Materials and Methods: The study is built upon an analysis of current literature, clinical trials, meta-analyses, and systematic reviews as well as press reports from various sources. Data were collected from studies examining the effects of obesity on fertility, as well as the impact of GLP-1 analogs on both fertility and obesity.
Basic Results: GLP-1 analogs promote weight management among obese and overweight patients leading to improvement in their fertility. Furthermore, they improve pregnancy rates in women with PCOS, although further examination is needed.
Conclusions: We observe, GLP-1 analogs are often used in regulation of type 2 diabetes. They have proven their ability to impact a variety of hormonal as well as metabolic pathways. They manage glucose metabolism, appetite, as well as insulin secretion. Alongside their metabolic influence, research demonstrates that GLP-1 analogs may have an effect on the reproductive system, involving fertility via metabolic and hormonal pathways.
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| format | Article |
| id | doaj-art-edfad09582d94341ad1973329c3ba890 |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-edfad09582d94341ad1973329c3ba8902025-02-12T08:26:08ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-02-013810.12775/QS.2025.38.58325GLP-1 Receptor Agonists’ Impact on Fertility - A ReviewJoanna Wojda0https://orcid.org/0009-0006-2662-8893Katarzyna Lesiczka-Fedoryj1https://orcid.org/0009-0004-4213-3028Anna Walczak2https://orcid.org/0009-0004-4554-9598Zuzanna Kościuszko3https://orcid.org/0009-0008-1490-8569Adam Sobiński4https://orcid.org/0009-0003-3063-5621Matylda Czerwonka5https://orcid.org/0009-0000-9738-9646Katarzyna Kurza6https://orcid.org/0009-0009-0075-2257Julianna Podolec7https://orcid.org/0009-0000-6980-7046Silvia Ciraolo8https://orcid.org/0009-0005-7010-5195Agnieszka Kulczycka-Rowicka9https://orcid.org/0009-0009-8917-4042University Clinical Hospital in Bialystok: Białystok, PL Maria Skłodowska- Curie 24A, 15-276 BialystokHospital in Puszczykowo: Puszczykowo, PLŚniadeckiego Voivodeship Hospital in Bialystok: Białystok, PLFlorian Ceynowy Specialist Hospital in Wejherowo: Wejherowo, PLMEDAR Private Healthcare Facility in LeczycaŚniadeckiego Voivodeship Hospital in BiałystokIndependent Public Health Care Facility in MysleniceUniversity Clinical Hospital in BialystokUniversity Clinical Hospital in Bialystok: Bialystok, PL Maria Skłodowska- Curie 24A, 15-276 BialystokŚniadeckiego Voivodeship Hospital in Bialystok: Białystok Purpose of Research: The aim of the research is to summarize the impact of GLP-1 analogs on fertility according to clinical studies, particularly in obese or overweight women with PCOS. Research Materials and Methods: The study is built upon an analysis of current literature, clinical trials, meta-analyses, and systematic reviews as well as press reports from various sources. Data were collected from studies examining the effects of obesity on fertility, as well as the impact of GLP-1 analogs on both fertility and obesity. Basic Results: GLP-1 analogs promote weight management among obese and overweight patients leading to improvement in their fertility. Furthermore, they improve pregnancy rates in women with PCOS, although further examination is needed. Conclusions: We observe, GLP-1 analogs are often used in regulation of type 2 diabetes. They have proven their ability to impact a variety of hormonal as well as metabolic pathways. They manage glucose metabolism, appetite, as well as insulin secretion. Alongside their metabolic influence, research demonstrates that GLP-1 analogs may have an effect on the reproductive system, involving fertility via metabolic and hormonal pathways. https://apcz.umk.pl/QS/article/view/58325GLP-1 analogfertilityobesityPCOS |
| spellingShingle | Joanna Wojda Katarzyna Lesiczka-Fedoryj Anna Walczak Zuzanna Kościuszko Adam Sobiński Matylda Czerwonka Katarzyna Kurza Julianna Podolec Silvia Ciraolo Agnieszka Kulczycka-Rowicka GLP-1 Receptor Agonists’ Impact on Fertility - A Review Quality in Sport GLP-1 analog fertility obesity PCOS |
| title | GLP-1 Receptor Agonists’ Impact on Fertility - A Review |
| title_full | GLP-1 Receptor Agonists’ Impact on Fertility - A Review |
| title_fullStr | GLP-1 Receptor Agonists’ Impact on Fertility - A Review |
| title_full_unstemmed | GLP-1 Receptor Agonists’ Impact on Fertility - A Review |
| title_short | GLP-1 Receptor Agonists’ Impact on Fertility - A Review |
| title_sort | glp 1 receptor agonists impact on fertility a review |
| topic | GLP-1 analog fertility obesity PCOS |
| url | https://apcz.umk.pl/QS/article/view/58325 |
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