A preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorder

In the latest autism observation, autism spectrum disorder (ASD) is more frequently diagnosed in males than in females. Efforts have been made in recent years to detect specific clinical patterns in females, improving their detection and diagnosis. Despite advancements, there are still challenges in...

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Main Authors: Alberto Sánchez-Pedroche, Eva Aguilar-Mediavilla, Mario Valera-Pozo, Daniel Adrover-Roig, Magdalena Valverde-Gómez
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Psychology
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyg.2025.1472646/full
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author Alberto Sánchez-Pedroche
Eva Aguilar-Mediavilla
Mario Valera-Pozo
Daniel Adrover-Roig
Magdalena Valverde-Gómez
author_facet Alberto Sánchez-Pedroche
Eva Aguilar-Mediavilla
Mario Valera-Pozo
Daniel Adrover-Roig
Magdalena Valverde-Gómez
author_sort Alberto Sánchez-Pedroche
collection DOAJ
description In the latest autism observation, autism spectrum disorder (ASD) is more frequently diagnosed in males than in females. Efforts have been made in recent years to detect specific clinical patterns in females, improving their detection and diagnosis. Despite advancements, there are still challenges in detecting ASD in females. This preliminary study explores whether the age at the time of diagnosis of ASD in females is related to a higher severity index compared to male participants. A total of 202 participants (52 females; M = 5.51) in Spain underwent ADOS-2 assessment for ASD clinical severity. The results indicate a significant inverse association between the severity index and the age of diagnosis, which was independent of sex. Despite this, the present results revealed that the age at diagnosis was higher in females compared to males. Further analyses also revealed a tendency toward higher severity levels in females. Factors contributing to this difference in the age of diagnosis of ASD between females and males are discussed concerning the presumed differential characteristics of ASD in females.
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publisher Frontiers Media S.A.
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series Frontiers in Psychology
spelling doaj-art-ee0419495c594774a18049524bbed2362025-02-10T06:48:45ZengFrontiers Media S.A.Frontiers in Psychology1664-10782025-02-011610.3389/fpsyg.2025.14726461472646A preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorderAlberto Sánchez-Pedroche0Eva Aguilar-Mediavilla1Mario Valera-Pozo2Daniel Adrover-Roig3Magdalena Valverde-Gómez4Department of Applied Pedagogy and Educational Psychology, Institute for Educational Research and Innovation (IRIE), University of the Balearic Islands, Palma, SpainDepartment of Applied Pedagogy and Educational Psychology, Institute for Educational Research and Innovation (IRIE), University of the Balearic Islands, Palma, SpainDepartment of Applied Pedagogy and Educational Psychology, Institute for Educational Research and Innovation (IRIE), University of the Balearic Islands, Palma, SpainDepartment of Applied Pedagogy and Educational Psychology, Institute for Educational Research and Innovation (IRIE), University of the Balearic Islands, Palma, SpainInstitute of Child and Adolescent Mental Health, Can Misses Hospital, Ibiza, SpainIn the latest autism observation, autism spectrum disorder (ASD) is more frequently diagnosed in males than in females. Efforts have been made in recent years to detect specific clinical patterns in females, improving their detection and diagnosis. Despite advancements, there are still challenges in detecting ASD in females. This preliminary study explores whether the age at the time of diagnosis of ASD in females is related to a higher severity index compared to male participants. A total of 202 participants (52 females; M = 5.51) in Spain underwent ADOS-2 assessment for ASD clinical severity. The results indicate a significant inverse association between the severity index and the age of diagnosis, which was independent of sex. Despite this, the present results revealed that the age at diagnosis was higher in females compared to males. Further analyses also revealed a tendency toward higher severity levels in females. Factors contributing to this difference in the age of diagnosis of ASD between females and males are discussed concerning the presumed differential characteristics of ASD in females.https://www.frontiersin.org/articles/10.3389/fpsyg.2025.1472646/fullASDfemale genderdiagnosisseverity indexchild and adolescentsex differences
spellingShingle Alberto Sánchez-Pedroche
Eva Aguilar-Mediavilla
Mario Valera-Pozo
Daniel Adrover-Roig
Magdalena Valverde-Gómez
A preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorder
Frontiers in Psychology
ASD
female gender
diagnosis
severity index
child and adolescent
sex differences
title A preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorder
title_full A preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorder
title_fullStr A preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorder
title_full_unstemmed A preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorder
title_short A preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorder
title_sort preliminary study on the relationship between symptom severity and age of diagnosis in females versus males with autistic spectrum disorder
topic ASD
female gender
diagnosis
severity index
child and adolescent
sex differences
url https://www.frontiersin.org/articles/10.3389/fpsyg.2025.1472646/full
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