Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease

Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease

Abstract Background: Melatonin (MLT) can improve mitophagy, thereby ameliorating cognitive deficits in Alzheimer’s disease (AD) patients. Hence, our research focused on the potential value of MLT-related genes (MRGs) in AD through bioinformatic analysis. Methods: First, the key cells in the single-c...

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Bibliographic Details
Main Authors: Hua-xiong Zhang, Dilmurat Hamit, Qing Li, Xiao Hu, San-feng Li, Fu Xu, Ming-yuan Wang, Guo-qing Bao, Hong-yan Li
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Alzheimer’s disease
MLT
Mendelian randomization
Biomarker
Molecular docking
Online Access:https://doi.org/10.1038/s41598-024-80755-x
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