The early warning paradox

Machine learning models in healthcare aim to predict critical outcomes but often overlook existing Early Warning Systems’ impact. Using data from King’s College Hospital, we demonstrate how current evaluation methods can lead to paradoxical results. We discuss challenges in developing ML models from...

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Bibliographic Details
Main Authors: Hugh Logan Ellis, Edward Palmer, James T. Teo, Martin Whyte, Kenneth Rockwood, Zina Ibrahim
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-024-01408-x
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Summary:Machine learning models in healthcare aim to predict critical outcomes but often overlook existing Early Warning Systems’ impact. Using data from King’s College Hospital, we demonstrate how current evaluation methods can lead to paradoxical results. We discuss challenges in developing ML models from retrospective data and propose a novel approach focused on identifying when patients enter a ‘risk state’ through latent health representations, potentially transforming clinical decision-making.
ISSN:2398-6352