RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASE
Background: Chronic kidney disease (CKD) is associated with impairment of mineral metabolism that, in turn, may result in the derangement of bone density, i.e. osteopenia or osteoporosis. Purpose: The objective of this study is to assess the impairment of bone density in male patients underwent ro...
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Universitas Airlangga
2019-12-01
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| Series: | Journal Orthopaedi and Traumatology Surabaya |
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| Online Access: | https://e-journal.unair.ac.id/JOINTS/article/view/16568 |
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| author | Patritius Kelik Dwi Santo Ismoyo Sugeng Yuwana |
| author_facet | Patritius Kelik Dwi Santo Ismoyo Sugeng Yuwana |
| author_sort | Patritius Kelik Dwi Santo Ismoyo |
| collection | DOAJ |
| description | Background: Chronic kidney disease (CKD) is associated with impairment of mineral metabolism that, in turn, may result in the derangement of bone density, i.e. osteopenia or osteoporosis.
Purpose: The objective of this study is to assess the impairment of bone density in male patients underwent routine hemodialysis due to stage V CKD.
Methods: Subjects in this cross sectional study were male patients underwent routine hemodialysis in Hemodialysis Unit Dr. Sardjito General Hospital Yogyakarta in June 2014. Subjects were invited when they were over 18 years old and had undergone hemodialysis for at least 6 months. Bone density of lumbar spine, total hip and femoral neck were assessed using DEXA. We collected information on age and the etiology of the CKD from medical records. Body weight and height were measured using calibrated apparatus. Data were analyzed using OpenEpi.
Results: We invited 30 male patients with mean (SD) age of 56.8 (13.8) years. Bone density of lumbar spine and femoral neck were significantly associated with the duration of hemodialysis, i.e. OR (95% CI) of 31.7 (3.8-856.0), p=0.0003 and 12.0 (1.9-111.0), p=0.005, respectively for those underwent hemodialysis of more than 12 months. Obesity was only protective for the bone density of the total hip, OR(95%CI) of 0.1 (0.004-0.9), p=0.03. There was no association between the etiology of the CKD and the decrease in bone density.
Conclusion: This study observed significant association between the duration of hemodialysis and bone density. |
| format | Article |
| id | doaj-art-f1c96fedafd64095bd6a57a1e610090e |
| institution | Kabale University |
| issn | 2722-712X 2460-8742 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Journal Orthopaedi and Traumatology Surabaya |
| spelling | doaj-art-f1c96fedafd64095bd6a57a1e610090e2025-02-12T07:29:22ZengUniversitas AirlanggaJournal Orthopaedi and Traumatology Surabaya2722-712X2460-87422019-12-017212513110.20473/joints.v7i2.2018.125-13113518RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASEPatritius Kelik Dwi Santo Ismoyo0Sugeng Yuwana1SMF/ Divisi Orthopaedi dan Traumatologi, Departemen Bedah, RSUP Dr. Sardjito/ Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan Universitas Gadjah Mada, YogyakartaSMF/ Divisi Orthopaedi dan Traumatologi, Departemen Bedah, RSUP Dr. Sardjito/ Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan Universitas Gadjah Mada, YogyakartaBackground: Chronic kidney disease (CKD) is associated with impairment of mineral metabolism that, in turn, may result in the derangement of bone density, i.e. osteopenia or osteoporosis. Purpose: The objective of this study is to assess the impairment of bone density in male patients underwent routine hemodialysis due to stage V CKD. Methods: Subjects in this cross sectional study were male patients underwent routine hemodialysis in Hemodialysis Unit Dr. Sardjito General Hospital Yogyakarta in June 2014. Subjects were invited when they were over 18 years old and had undergone hemodialysis for at least 6 months. Bone density of lumbar spine, total hip and femoral neck were assessed using DEXA. We collected information on age and the etiology of the CKD from medical records. Body weight and height were measured using calibrated apparatus. Data were analyzed using OpenEpi. Results: We invited 30 male patients with mean (SD) age of 56.8 (13.8) years. Bone density of lumbar spine and femoral neck were significantly associated with the duration of hemodialysis, i.e. OR (95% CI) of 31.7 (3.8-856.0), p=0.0003 and 12.0 (1.9-111.0), p=0.005, respectively for those underwent hemodialysis of more than 12 months. Obesity was only protective for the bone density of the total hip, OR(95%CI) of 0.1 (0.004-0.9), p=0.03. There was no association between the etiology of the CKD and the decrease in bone density. Conclusion: This study observed significant association between the duration of hemodialysis and bone density.https://e-journal.unair.ac.id/JOINTS/article/view/16568chronic kidney diseasehemodialysisbone mineral densitydexa |
| spellingShingle | Patritius Kelik Dwi Santo Ismoyo Sugeng Yuwana RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASE Journal Orthopaedi and Traumatology Surabaya chronic kidney disease hemodialysis bone mineral density dexa |
| title | RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASE |
| title_full | RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASE |
| title_fullStr | RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASE |
| title_full_unstemmed | RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASE |
| title_short | RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASE |
| title_sort | risk factors for impaired bone density in male patients underwent hemodialysis due to chronic kidney disease |
| topic | chronic kidney disease hemodialysis bone mineral density dexa |
| url | https://e-journal.unair.ac.id/JOINTS/article/view/16568 |
| work_keys_str_mv | AT patritiuskelikdwisantoismoyo riskfactorsforimpairedbonedensityinmalepatientsunderwenthemodialysisduetochronickidneydisease AT sugengyuwana riskfactorsforimpairedbonedensityinmalepatientsunderwenthemodialysisduetochronickidneydisease |