Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia
Background: Pain is common in Major Depressive Disorder (MDD), but other related factors have received scant attention. The aim was to know the factors related to Painful Somatic Symptoms (PSS) in MDD patients, especially gender and anhedonia. Methods: Cross-sectional study in MDD patients (DSM-5) w...
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Elsevier
2025-03-01
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| Series: | Psychiatry Research Communications |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772598725000030 |
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| author | A. Pérez-Morenilla A. Salazar I. Failde F. González-Sáiz J.A. Micó |
| author_facet | A. Pérez-Morenilla A. Salazar I. Failde F. González-Sáiz J.A. Micó |
| author_sort | A. Pérez-Morenilla |
| collection | DOAJ |
| description | Background: Pain is common in Major Depressive Disorder (MDD), but other related factors have received scant attention. The aim was to know the factors related to Painful Somatic Symptoms (PSS) in MDD patients, especially gender and anhedonia. Methods: Cross-sectional study in MDD patients (DSM-5) with positive screening on the Hospital Anxiety and Depression Scale (HADS). Anhedonia (SHAPS), somatic symptoms (SSI-28), and Quality of Life (QoL; SF-36) were evaluated. A multiple linear regression model was used to identify factors related to PSS. Results: In N = 111 patients, PSS were related to gender, rheumatic disease and anxiety, and worsened QoL. Anhedonia was detected in 93 patients (83.8%), with no significant gender differences in PSS. However, compared to men, depressed women with anhedonia had significantly higher scores on the SSI-28 and the non-painful somatic symptom scale (SSI-21). In the group without anhedonia (n = 18), a higher percentage of women had PSS. Conclusions: Some factors, including gender or anhedonia, influence the presence of PSS in MDD patients. In depressed patients with anhedonia, gender differences in the perception of pain were smaller than in patients without anhedonia. This suggests a diminished capacity to perceive pain. This small difference between gender was not evidenced for non-painful somatic symptoms. |
| format | Article |
| id | doaj-art-f5037e0f25914333b7ad3589396452d3 |
| institution | Kabale University |
| issn | 2772-5987 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
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| series | Psychiatry Research Communications |
| spelling | doaj-art-f5037e0f25914333b7ad3589396452d32025-02-09T05:01:43ZengElsevierPsychiatry Research Communications2772-59872025-03-0151100204Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedoniaA. Pérez-Morenilla0A. Salazar1I. Failde2F. González-Sáiz3J.A. Micó4Department of Psychiatry, University Hospital of Jerez de La Frontera, Cádiz, Spain; Biomedical Research and Innovation Institute of Cádiz (INiBICA), Research Unit, Puerta Del Mar University Hospital, University of Cadiz, SpainBiomedical Research and Innovation Institute of Cádiz (INiBICA), Research Unit, Puerta Del Mar University Hospital, University of Cadiz, Spain; The Observatory of Pain, University of Cádiz, Spain; Department of Statistics and Operational Research, University of Cádiz, Spain; Corresponding author. Department of Statistic and Operational Research. University of Cádiz. Av. Universidad de Cádiz, 10, Puerto Real, 11519, Cádiz, Spain.Biomedical Research and Innovation Institute of Cádiz (INiBICA), Research Unit, Puerta Del Mar University Hospital, University of Cadiz, Spain; The Observatory of Pain, University of Cádiz, SpainDepartment of Psychiatry, University Hospital of Jerez de La Frontera, Cádiz, Spain; Biomedical Research and Innovation Institute of Cádiz (INiBICA), Research Unit, Puerta Del Mar University Hospital, University of Cadiz, Spain; Department of Neuroscience, Pharmacology and Psychiatry, School of Medicine, University of Cádiz, Spain; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Cádiz, SpainBiomedical Research and Innovation Institute of Cádiz (INiBICA), Research Unit, Puerta Del Mar University Hospital, University of Cadiz, Spain; Department of Neuroscience, Pharmacology and Psychiatry, School of Medicine, University of Cádiz, Spain; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Cádiz, SpainBackground: Pain is common in Major Depressive Disorder (MDD), but other related factors have received scant attention. The aim was to know the factors related to Painful Somatic Symptoms (PSS) in MDD patients, especially gender and anhedonia. Methods: Cross-sectional study in MDD patients (DSM-5) with positive screening on the Hospital Anxiety and Depression Scale (HADS). Anhedonia (SHAPS), somatic symptoms (SSI-28), and Quality of Life (QoL; SF-36) were evaluated. A multiple linear regression model was used to identify factors related to PSS. Results: In N = 111 patients, PSS were related to gender, rheumatic disease and anxiety, and worsened QoL. Anhedonia was detected in 93 patients (83.8%), with no significant gender differences in PSS. However, compared to men, depressed women with anhedonia had significantly higher scores on the SSI-28 and the non-painful somatic symptom scale (SSI-21). In the group without anhedonia (n = 18), a higher percentage of women had PSS. Conclusions: Some factors, including gender or anhedonia, influence the presence of PSS in MDD patients. In depressed patients with anhedonia, gender differences in the perception of pain were smaller than in patients without anhedonia. This suggests a diminished capacity to perceive pain. This small difference between gender was not evidenced for non-painful somatic symptoms.http://www.sciencedirect.com/science/article/pii/S2772598725000030 |
| spellingShingle | A. Pérez-Morenilla A. Salazar I. Failde F. González-Sáiz J.A. Micó Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia Psychiatry Research Communications |
| title | Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia |
| title_full | Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia |
| title_fullStr | Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia |
| title_full_unstemmed | Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia |
| title_short | Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia |
| title_sort | factors related to painful somatic symptoms in patients with depression the role of gender and anhedonia |
| url | http://www.sciencedirect.com/science/article/pii/S2772598725000030 |
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