Jack London and White Fang: a lost struggle

The California State Parks curators granted access to artifacts owned by Jack London that are in storage in their Sonoma Barracks in Sonoma, CA. A medicine case, drug vials, and various paper documents that covered the period of his life from 1906 to 1915 were examined for drug residues left on thei...

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Main Authors: Zilberstein, Gleb, Zilberstein, Svetlana, Rocco, Richard M., Righetti, Pier Giorgio
Format: Article
Language:English
Published: Académie des sciences 2022-04-01
Series:Comptes Rendus. Chimie
Subjects:
Online Access:https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.164/
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author Zilberstein, Gleb
Zilberstein, Svetlana
Rocco, Richard M.
Righetti, Pier Giorgio
author_facet Zilberstein, Gleb
Zilberstein, Svetlana
Rocco, Richard M.
Righetti, Pier Giorgio
author_sort Zilberstein, Gleb
collection DOAJ
description The California State Parks curators granted access to artifacts owned by Jack London that are in storage in their Sonoma Barracks in Sonoma, CA. A medicine case, drug vials, and various paper documents that covered the period of his life from 1906 to 1915 were examined for drug residues left on their surface. All the objects were tested with the non-invasive surface analysis EVA (ethylene-vinyl acetate) technology, which consist of a foil studded with ground mixed-bed cation/anion exchangers as well as with C$_{8}$ and C$_{18}$ resins. The harvested material collected by the foils was analysed via GC-MS and the following 12 drugs were identified: N-(4-ethoxyphenyl) acetamide, phenyl salicylic acid, morphine, 6-monoacetylmorphine, 3-acetylmorphine, diacetylmorphine, dipenteneglycol, quinine dihydrochloride, quinine base, atropine, scopolamine and hyoscyamine. Despite the claims by his biographers that he used opium, morphine, and heroin on a regular basis this assertion could not be confirmed by the chemical analyses of the objects here tested. Only two opioids were discovered, morphine and diacetylmorphine (heroin) both of which could have been derived from the use of common, legal (over-the-counter) flu and cough medications.
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spelling doaj-art-f9471924d2fb4bd4a360df80e494d0192025-02-07T13:31:13ZengAcadémie des sciencesComptes Rendus. Chimie1878-15432022-04-0125G111512310.5802/crchim.16410.5802/crchim.164Jack London and White Fang: a lost struggleZilberstein, Gleb0Zilberstein, Svetlana1Rocco, Richard M.2Righetti, Pier Giorgio3https://orcid.org/0000-0001-8321-9187Spectrophon Ltd, Oppenheimer 7, Rehovot 7670107, IsraelSpringStyle Tech Design Ltd, Rehovot 7670107, IsraelSamuel Merritt University, Oakland, California, USADepartment of Chemistry, Materials and Chemical Engineering “Giulio Natta”, Politecnico di Milano, Via Mancinelli 7, Milano 20131, ItalyThe California State Parks curators granted access to artifacts owned by Jack London that are in storage in their Sonoma Barracks in Sonoma, CA. A medicine case, drug vials, and various paper documents that covered the period of his life from 1906 to 1915 were examined for drug residues left on their surface. All the objects were tested with the non-invasive surface analysis EVA (ethylene-vinyl acetate) technology, which consist of a foil studded with ground mixed-bed cation/anion exchangers as well as with C$_{8}$ and C$_{18}$ resins. The harvested material collected by the foils was analysed via GC-MS and the following 12 drugs were identified: N-(4-ethoxyphenyl) acetamide, phenyl salicylic acid, morphine, 6-monoacetylmorphine, 3-acetylmorphine, diacetylmorphine, dipenteneglycol, quinine dihydrochloride, quinine base, atropine, scopolamine and hyoscyamine. Despite the claims by his biographers that he used opium, morphine, and heroin on a regular basis this assertion could not be confirmed by the chemical analyses of the objects here tested. Only two opioids were discovered, morphine and diacetylmorphine (heroin) both of which could have been derived from the use of common, legal (over-the-counter) flu and cough medications.https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.164/Jack London deathMorphineScopolamineHyoscyamineAtropineQuinineDiacetylmorphine
spellingShingle Zilberstein, Gleb
Zilberstein, Svetlana
Rocco, Richard M.
Righetti, Pier Giorgio
Jack London and White Fang: a lost struggle
Comptes Rendus. Chimie
Jack London death
Morphine
Scopolamine
Hyoscyamine
Atropine
Quinine
Diacetylmorphine
title Jack London and White Fang: a lost struggle
title_full Jack London and White Fang: a lost struggle
title_fullStr Jack London and White Fang: a lost struggle
title_full_unstemmed Jack London and White Fang: a lost struggle
title_short Jack London and White Fang: a lost struggle
title_sort jack london and white fang a lost struggle
topic Jack London death
Morphine
Scopolamine
Hyoscyamine
Atropine
Quinine
Diacetylmorphine
url https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.164/
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