A simple route to 7-substituted Quinolin-2(1H)-ones from Meta-substituted anilines
Meta-substituted anilines are condensed with methyl 3,3-dimethoxypropionate in a two-step acylation, cyclization sequence to preferentially form 7-substituted quinolinones in an isomeric mixture with 5-substituted quinolinones. The product ratios in this previously unexplored class of substrates dep...
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Main Authors: | Marisol Varela Ausec, Mary K. Payne, Jason R. Stewart, Olivia M. Galando, Eliott J. Wright, Sara E.S. Martin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
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Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625000724 |
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