Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral Artery

Background: Mechanical thrombectomy has been established as a safe, standard and effective treatment option for occlusions of the proximal segment of the middle cerebral artery (MCA), as demonstrated in numerous studies. However, performing thrombectomy in the M2 divisions of MCA presents inherent...

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Main Authors: Bheru Dan Charan, Shailesh B Gaikwad, Savyasachi Jain, Ajay Garg, Leve Joseph Devarajan Sebastian, M V Padma Srivastava, Rohit Bhatia, Awadh Kishore Pandit, Shashank Sarad Kale
Format: Article
Language:English
Published: Vilnius University Press 2024-05-01
Series:Acta Medica Lituanica
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Online Access:https://www.zurnalai.vu.lt/AML/article/view/34674
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author Bheru Dan Charan
Shailesh B Gaikwad
Savyasachi Jain
Ajay Garg
Leve Joseph Devarajan Sebastian
M V Padma Srivastava
Rohit Bhatia
Awadh Kishore Pandit
Shashank Sarad Kale
author_facet Bheru Dan Charan
Shailesh B Gaikwad
Savyasachi Jain
Ajay Garg
Leve Joseph Devarajan Sebastian
M V Padma Srivastava
Rohit Bhatia
Awadh Kishore Pandit
Shashank Sarad Kale
author_sort Bheru Dan Charan
collection DOAJ
description Background: Mechanical thrombectomy has been established as a safe, standard and effective treatment option for occlusions of the proximal segment of the middle cerebral artery (MCA), as demonstrated in numerous studies. However, performing thrombectomy in the M2 divisions of MCA presents inherent challenges. In this institutional experience, we aim to delineate the recanalisation rates achieved through mechanical thrombectomy in cases involving the M2 segment of the MCA.Methods: We conducted a retrospective analysis of patients who underwent thrombectomy due to M2 MCA occlusions in the period from January 2018 to December 2021. Various factors affecting recanalisation rates were assessed.Results: A total of 15 patients with M2 segment occlusions of the middle cerebral artery were included in the study, comprising 11 in the superior division and 4 in the inferior division. The successful recanalisation rate was 72.33%, with notably higher success observed in cases of inferior division occlusion. The primary outcome of our study was the mTICI recanalisation status, categorised as successful recanalisation (mTICI = 2b or mTICI = 3) and unsuccessful recanalisation (mTICI = 1 or mTICI = 2a) and mRS at 6 months. None of the predictors assessed reached statistical significance.Conclusions: Mechanical thrombectomy demonstrates favourable efficacy and recanalisation rates in cases of M2 MCA division occlusion. Notably, inferior division occlusions exhibit a higher likelihood of successful recanalisation.
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spelling doaj-art-fa820bd6299b49feb6e8888ed9db0c702025-02-11T18:08:38ZengVilnius University PressActa Medica Lituanica1392-01382029-41742024-05-0131110.15388/Amed.2024.31.1.18Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral ArteryBheru Dan Charan0https://orcid.org/0009-0002-8711-2023Shailesh B Gaikwad1Savyasachi Jain2Ajay Garg3https://orcid.org/0000-0002-9385-291XLeve Joseph Devarajan Sebastian4M V Padma Srivastava5Rohit Bhatia6Awadh Kishore Pandit7Shashank Sarad Kale8Department of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neuroimaging & Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India Background: Mechanical thrombectomy has been established as a safe, standard and effective treatment option for occlusions of the proximal segment of the middle cerebral artery (MCA), as demonstrated in numerous studies. However, performing thrombectomy in the M2 divisions of MCA presents inherent challenges. In this institutional experience, we aim to delineate the recanalisation rates achieved through mechanical thrombectomy in cases involving the M2 segment of the MCA.Methods: We conducted a retrospective analysis of patients who underwent thrombectomy due to M2 MCA occlusions in the period from January 2018 to December 2021. Various factors affecting recanalisation rates were assessed.Results: A total of 15 patients with M2 segment occlusions of the middle cerebral artery were included in the study, comprising 11 in the superior division and 4 in the inferior division. The successful recanalisation rate was 72.33%, with notably higher success observed in cases of inferior division occlusion. The primary outcome of our study was the mTICI recanalisation status, categorised as successful recanalisation (mTICI = 2b or mTICI = 3) and unsuccessful recanalisation (mTICI = 1 or mTICI = 2a) and mRS at 6 months. None of the predictors assessed reached statistical significance.Conclusions: Mechanical thrombectomy demonstrates favourable efficacy and recanalisation rates in cases of M2 MCA division occlusion. Notably, inferior division occlusions exhibit a higher likelihood of successful recanalisation. https://www.zurnalai.vu.lt/AML/article/view/34674Ischemic strokerecanalizationMT mechanical thrombectomy
spellingShingle Bheru Dan Charan
Shailesh B Gaikwad
Savyasachi Jain
Ajay Garg
Leve Joseph Devarajan Sebastian
M V Padma Srivastava
Rohit Bhatia
Awadh Kishore Pandit
Shashank Sarad Kale
Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral Artery
Acta Medica Lituanica
Ischemic stroke
recanalization
MT mechanical thrombectomy
title Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral Artery
title_full Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral Artery
title_fullStr Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral Artery
title_full_unstemmed Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral Artery
title_short Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral Artery
title_sort mechanical thrombectomy in medium vessels occlusion mevos an institutional experience with m2 divisions of middle cerebral artery
topic Ischemic stroke
recanalization
MT mechanical thrombectomy
url https://www.zurnalai.vu.lt/AML/article/view/34674
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