Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis

Introduction Knee osteoarthritis (KOA) is one of the leading causes of disability. The effectiveness of acupuncture for treating KOA remains controversial. This protocol describes the method of a systematic review and meta-analysis evaluating the effectiveness and safety of acupuncture for treating...

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Main Authors: Jing-Wen Yang, Jian-Feng Tu, Myeong Soo Lee, Chuan-Yang Liu, Ling-Yu Qi, Fang-Ting Yu, Shi-Yan Yan, Jin-Ling Li, Lu-Lu Lin, Xiao-Wan Hao, Xin-Tong Su, Li-Qiong Wang
Format: Article
Language:English
Published: BMJ Publishing Group 2022-01-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/1/e052270.full
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author Jing-Wen Yang
Jian-Feng Tu
Myeong Soo Lee
Chuan-Yang Liu
Ling-Yu Qi
Fang-Ting Yu
Shi-Yan Yan
Jin-Ling Li
Lu-Lu Lin
Xiao-Wan Hao
Xin-Tong Su
Li-Qiong Wang
author_facet Jing-Wen Yang
Jian-Feng Tu
Myeong Soo Lee
Chuan-Yang Liu
Ling-Yu Qi
Fang-Ting Yu
Shi-Yan Yan
Jin-Ling Li
Lu-Lu Lin
Xiao-Wan Hao
Xin-Tong Su
Li-Qiong Wang
author_sort Jing-Wen Yang
collection DOAJ
description Introduction Knee osteoarthritis (KOA) is one of the leading causes of disability. The effectiveness of acupuncture for treating KOA remains controversial. This protocol describes the method of a systematic review and meta-analysis evaluating the effectiveness and safety of acupuncture for treating KOA.Methods and analysis Four English databases (PubMed, Embase, Cochrane Library databases and Web of Science) and four Chinese databases (China National Knowledge Infrastructure, Chinese Biomedical Literature Database, VIP Database for Chinese Technical Periodicals, and Wanfang) will be searched from the database inception to 1 September 2021. All randomised controlled trials related to acupuncture for KOA will be included. Extracted data will include publication details, basic information, demographic data, intervention details and patient outcomes. The primary outcome will be pain intensity. Risk of bias will be assessed using the Cochrane Collaboration’s tool for assessing risk of bias. Article selection, data extraction and risk of bias assessment will be performed in duplicate by two independent reviewers. If the meta-analysis is precluded, we will conduct a descriptive synthesis using a best-evidence synthesis approach. The strength of recommendations and quality of evidence will be assessed using the Grading of Recommendations Assessment Development and Evaluation working group methodology.Ethics and dissemination Ethics approval is not required because individual patient data are not included. This protocol was registered in the international Prospective Register of Systematic Reviews on 25 February 2021. The systematic review and meta-analysis will be submitted for publication in a peer-reviewed journal. The findings will also be disseminated through conference presentations.Trial registration number CRD42021232177.
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spelling doaj-art-fceafec014c74b578cbe57bcb6b8e1372025-02-07T00:45:10ZengBMJ Publishing GroupBMJ Open2044-60552022-01-0112110.1136/bmjopen-2021-052270Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysisJing-Wen Yang0Jian-Feng Tu1Myeong Soo Lee2Chuan-Yang Liu3Ling-Yu Qi4Fang-Ting Yu5Shi-Yan Yan6Jin-Ling Li7Lu-Lu Lin8Xiao-Wan Hao9Xin-Tong Su10Li-Qiong Wang11International Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaInternational Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, KoreaSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China1 International Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaInternational Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China1 International Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaIntroduction Knee osteoarthritis (KOA) is one of the leading causes of disability. The effectiveness of acupuncture for treating KOA remains controversial. This protocol describes the method of a systematic review and meta-analysis evaluating the effectiveness and safety of acupuncture for treating KOA.Methods and analysis Four English databases (PubMed, Embase, Cochrane Library databases and Web of Science) and four Chinese databases (China National Knowledge Infrastructure, Chinese Biomedical Literature Database, VIP Database for Chinese Technical Periodicals, and Wanfang) will be searched from the database inception to 1 September 2021. All randomised controlled trials related to acupuncture for KOA will be included. Extracted data will include publication details, basic information, demographic data, intervention details and patient outcomes. The primary outcome will be pain intensity. Risk of bias will be assessed using the Cochrane Collaboration’s tool for assessing risk of bias. Article selection, data extraction and risk of bias assessment will be performed in duplicate by two independent reviewers. If the meta-analysis is precluded, we will conduct a descriptive synthesis using a best-evidence synthesis approach. The strength of recommendations and quality of evidence will be assessed using the Grading of Recommendations Assessment Development and Evaluation working group methodology.Ethics and dissemination Ethics approval is not required because individual patient data are not included. This protocol was registered in the international Prospective Register of Systematic Reviews on 25 February 2021. The systematic review and meta-analysis will be submitted for publication in a peer-reviewed journal. The findings will also be disseminated through conference presentations.Trial registration number CRD42021232177.https://bmjopen.bmj.com/content/12/1/e052270.full
spellingShingle Jing-Wen Yang
Jian-Feng Tu
Myeong Soo Lee
Chuan-Yang Liu
Ling-Yu Qi
Fang-Ting Yu
Shi-Yan Yan
Jin-Ling Li
Lu-Lu Lin
Xiao-Wan Hao
Xin-Tong Su
Li-Qiong Wang
Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis
BMJ Open
title Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis
title_full Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis
title_fullStr Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis
title_full_unstemmed Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis
title_short Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis
title_sort is acupuncture effective for knee osteoarthritis a protocol for a systematic review and meta analysis
url https://bmjopen.bmj.com/content/12/1/e052270.full
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