Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center
Abstract Purpose Multidisciplinary tumor boards (MTB) are associated with improved outcomes. Yet, most patients in Western countries receive cancer care at non-academic medical centers. Guideline adherence of MTB recommendations in non-academic medical centers as well as factors contributing to non-...
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| Format: | Article |
| Language: | English |
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Springer
2024-12-01
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| Series: | Journal of Cancer Research and Clinical Oncology |
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| Online Access: | https://doi.org/10.1007/s00432-024-06049-x |
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| author | Carl-Stephan Leonhardt Leopold Lanzenberger Raphael Puehringer Ulla Klaiber Irene Hauser Oliver Strobel Gerald Prager Martin Bodingbauer |
| author_facet | Carl-Stephan Leonhardt Leopold Lanzenberger Raphael Puehringer Ulla Klaiber Irene Hauser Oliver Strobel Gerald Prager Martin Bodingbauer |
| author_sort | Carl-Stephan Leonhardt |
| collection | DOAJ |
| description | Abstract Purpose Multidisciplinary tumor boards (MTB) are associated with improved outcomes. Yet, most patients in Western countries receive cancer care at non-academic medical centers. Guideline adherence of MTB recommendations in non-academic medical centers as well as factors contributing to non-adherence remain largely unexplored. Methods This retrospective study followed the STROBE recommendations. All cases discussed at the MTB of the Landesklinikum Baden-Moedling, Austria, were eligible for inclusion. Guideline non-adherence was assessed by two reviewers independently using the AWMF S3 guidelines. Factors associated with guideline non-adherence were investigated using multivariable ordinal regression. Results In total, 579 patients were included in the final analysis: 486 were female (83.9%) and 93 were male (16.1%), with a median age of 70 years (IQR 60–80). Most had breast cancer (n = 451; 77.9%), while 128 had colorectal cancer (22.1%). Complete adherence to guidelines was observed in 453 patients (78.2%), major deviations in 60 (10.4%), and minor deviations in 66 (11.4%) patients. Non-adherence was primarily due to patient preferences (n = 24; 40.0%), lack of surgical treatment recommendation (n = 24; 40.0%), and comorbidities (n = 9; 15.0%). After adjusting for relevant variables, predictors of non-adherence included older age at diagnosis (OR 1.02, 95% CI 1.00–1.04), colorectal cancer (OR 3.84, 95% CI 1.99–7.42), higher ECOG status (OR 1.59, 95% CI 1.18–2.16), and a more recent MTB conference (OR 1.20, 95% CI 1.03–1.41). Conclusion Overall, guideline adherence was high for colorectal and breast cancer and comparable to results from academic medical centers. However, results need to be confirmed in other tumor entities. |
| format | Article |
| id | doaj-art-fe9fd29e70a243e48d5d37257eefe945 |
| institution | Kabale University |
| issn | 1432-1335 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Springer |
| record_format | Article |
| series | Journal of Cancer Research and Clinical Oncology |
| spelling | doaj-art-fe9fd29e70a243e48d5d37257eefe9452025-02-09T12:10:16ZengSpringerJournal of Cancer Research and Clinical Oncology1432-13352024-12-0115111910.1007/s00432-024-06049-xEvidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical centerCarl-Stephan Leonhardt0Leopold Lanzenberger1Raphael Puehringer2Ulla Klaiber3Irene Hauser4Oliver Strobel5Gerald Prager6Martin Bodingbauer7Department of Surgery, Landesklinikum Baden-MoedlingDepartment of Internal Medicine, Landesklinikum Baden-MoedlingDepartment of General Surgery, Medical University of ViennaDepartment of General Surgery, Medical University of ViennaDepartment of Internal Medicine, Landesklinikum Baden-MoedlingDepartment of General Surgery, Medical University of ViennaDivision of Oncology, Department of Internal Medicine I, Medical University of ViennaDepartment of Surgery, Landesklinikum Baden-MoedlingAbstract Purpose Multidisciplinary tumor boards (MTB) are associated with improved outcomes. Yet, most patients in Western countries receive cancer care at non-academic medical centers. Guideline adherence of MTB recommendations in non-academic medical centers as well as factors contributing to non-adherence remain largely unexplored. Methods This retrospective study followed the STROBE recommendations. All cases discussed at the MTB of the Landesklinikum Baden-Moedling, Austria, were eligible for inclusion. Guideline non-adherence was assessed by two reviewers independently using the AWMF S3 guidelines. Factors associated with guideline non-adherence were investigated using multivariable ordinal regression. Results In total, 579 patients were included in the final analysis: 486 were female (83.9%) and 93 were male (16.1%), with a median age of 70 years (IQR 60–80). Most had breast cancer (n = 451; 77.9%), while 128 had colorectal cancer (22.1%). Complete adherence to guidelines was observed in 453 patients (78.2%), major deviations in 60 (10.4%), and minor deviations in 66 (11.4%) patients. Non-adherence was primarily due to patient preferences (n = 24; 40.0%), lack of surgical treatment recommendation (n = 24; 40.0%), and comorbidities (n = 9; 15.0%). After adjusting for relevant variables, predictors of non-adherence included older age at diagnosis (OR 1.02, 95% CI 1.00–1.04), colorectal cancer (OR 3.84, 95% CI 1.99–7.42), higher ECOG status (OR 1.59, 95% CI 1.18–2.16), and a more recent MTB conference (OR 1.20, 95% CI 1.03–1.41). Conclusion Overall, guideline adherence was high for colorectal and breast cancer and comparable to results from academic medical centers. However, results need to be confirmed in other tumor entities.https://doi.org/10.1007/s00432-024-06049-xGuidelineGuideline adherenceHospitalsCommunityAcademic medical centersColorectal neoplasms |
| spellingShingle | Carl-Stephan Leonhardt Leopold Lanzenberger Raphael Puehringer Ulla Klaiber Irene Hauser Oliver Strobel Gerald Prager Martin Bodingbauer Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center Journal of Cancer Research and Clinical Oncology Guideline Guideline adherence Hospitals Community Academic medical centers Colorectal neoplasms |
| title | Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center |
| title_full | Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center |
| title_fullStr | Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center |
| title_full_unstemmed | Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center |
| title_short | Evidence-based cancer care: assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non-academic medical center |
| title_sort | evidence based cancer care assessing guideline adherence of multidisciplinary tumor board recommendations for breast and colorectal cancer in a non academic medical center |
| topic | Guideline Guideline adherence Hospitals Community Academic medical centers Colorectal neoplasms |
| url | https://doi.org/10.1007/s00432-024-06049-x |
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