Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure

Carrying a cellphone against the body has become commonplace in our world replete with smartphones. Acute and chronic health effects caused by these devices emitting radiofrequency radiation from multiple antennas have not been well evaluated. In this study, the popliteal vein of a healthy volunteer...

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Main Authors: Robert R. Brown, Barbara Biebrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1499499/full
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author Robert R. Brown
Robert R. Brown
Robert R. Brown
Barbara Biebrich
author_facet Robert R. Brown
Robert R. Brown
Robert R. Brown
Barbara Biebrich
author_sort Robert R. Brown
collection DOAJ
description Carrying a cellphone against the body has become commonplace in our world replete with smartphones. Acute and chronic health effects caused by these devices emitting radiofrequency radiation from multiple antennas have not been well evaluated. In this study, the popliteal vein of a healthy volunteer was imaged with ultrasonography prior to and following the placement of an idle, but active smartphone against her knee for 5 min. Pre-exposure longitudinal sonographic images demonstrate a normal anechoic lumen to the popliteal vein. Images obtained 5 min after direct skin exposure to the smartphone demonstrate a dramatic change in the acoustic appearance of the vessel. The interior of the vessel became coarsely hypoechoic with sluggish flow seen in real-time images, a typical sonographic appearance for rouleaux formation. A follow up examination performed 5 min after the subject walked around yielded continued rouleaux formation in the popliteal vein, albeit less dramatic than that observed immediately post exposure. This revolutionary in vivo method to assess radiofrequency radiation induced rouleaux formation should be further pursued in the general population to determine its prevalence and if its occurrence provides a unique biomarker of exposure that may predict morbidity.
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spelling doaj-art-ffa92dbae1a349e282925df6a31bb5b02025-02-11T07:00:13ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-02-011210.3389/fcvm.2025.14994991499499Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposureRobert R. Brown0Robert R. Brown1Robert R. Brown2Barbara Biebrich3Radiology Partners – Phoenix, Mesa, AZ, United StatesEnvironmental Health Trust, Jackson, WY, United StatesDepartment of Radiology, UPMC Hamot, Erie, PA, United StatesPueblo Medical Imaging, Las Vegas, NV, United StatesCarrying a cellphone against the body has become commonplace in our world replete with smartphones. Acute and chronic health effects caused by these devices emitting radiofrequency radiation from multiple antennas have not been well evaluated. In this study, the popliteal vein of a healthy volunteer was imaged with ultrasonography prior to and following the placement of an idle, but active smartphone against her knee for 5 min. Pre-exposure longitudinal sonographic images demonstrate a normal anechoic lumen to the popliteal vein. Images obtained 5 min after direct skin exposure to the smartphone demonstrate a dramatic change in the acoustic appearance of the vessel. The interior of the vessel became coarsely hypoechoic with sluggish flow seen in real-time images, a typical sonographic appearance for rouleaux formation. A follow up examination performed 5 min after the subject walked around yielded continued rouleaux formation in the popliteal vein, albeit less dramatic than that observed immediately post exposure. This revolutionary in vivo method to assess radiofrequency radiation induced rouleaux formation should be further pursued in the general population to determine its prevalence and if its occurrence provides a unique biomarker of exposure that may predict morbidity.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1499499/fullcellphonemobile phoneEMFsradiofrequency radiationwireless communicationrouleaux
spellingShingle Robert R. Brown
Robert R. Brown
Robert R. Brown
Barbara Biebrich
Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure
Frontiers in Cardiovascular Medicine
cellphone
mobile phone
EMFs
radiofrequency radiation
wireless communication
rouleaux
title Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure
title_full Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure
title_fullStr Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure
title_full_unstemmed Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure
title_short Hypothesis: ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure
title_sort hypothesis ultrasonography can document dynamic in vivo rouleaux formation due to mobile phone exposure
topic cellphone
mobile phone
EMFs
radiofrequency radiation
wireless communication
rouleaux
url https://www.frontiersin.org/articles/10.3389/fcvm.2025.1499499/full
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AT robertrbrown hypothesisultrasonographycandocumentdynamicinvivorouleauxformationduetomobilephoneexposure
AT barbarabiebrich hypothesisultrasonographycandocumentdynamicinvivorouleauxformationduetomobilephoneexposure