FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

“…Though the etiology of doxorubicin-dependent heart damage has yet to be fully elucidated, the ability of doxorubicin to damage DNA and trigger oxidative stress have been heavily implicated in the pathogenesis of chemotherapy-associated cardiomyopathy. …”
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ANALISIS KEMAMPUAN PENGUASAAN KONSEP IPA TERPADU DAN KEPEDULIAN LINGKUNGAN MAHASISWA MELALUI PENGGUNAAN BAHAN AJAR PENGOLAHAN TEBU SEBAGAI ENERGI TERBARUKAN by Lailatul Nuraini, Supeno Supeno, Sudarti Sudarti, Sri Astutik, Shinta Nuriyah Mahbubiyah Royani

“…It also showed that there was environment awareness toward local potential of sugar cane manufacturing as a renewable energy in Jember. The ability of mastery concept and environment awareness was very important to be had by students, so the students were able to integrate the science concept into environment awareness behaviour in the daily life. …”
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Lokalisasi Mobile Robot berdasarkan Citra Kamera OMNI menggunakan Fitur Surf by Susijanto Tri Rasmana, Harianto Harianto, Pauladie Susanto, Anan Pepe Abseno, Zendi Zakaria Raga Permana

“…The self-localization ability is used to determine the robot position in an area and as a reference to determine the next trip direction. …”
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Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study by Patricia Martins Bueno, Paulo Alceu Kiemle Trindade, Laís Hollara Medeiros, Leide Vilma Fidélis da Silva, Ivy Kiemle Trindade-Suedam

“…Three variables were evaluated: 1) Bite Force (BF) (measured in Newtons – N) presented as the average of the bite force from the right and left molars (x‾ RM + LM), using a gnathodynamometer (IDDK Kratos), 2) Masticatory Efficiency (ME) (ranging from 0 to 1, with values closer to 1 indicating poorer efficiency), assessed through a dual-color masticatory gum test analyzed visually and optoelectronically (ViewGum©), and 3) Masticatory Capacity (MC): patient-reported ability to chew, rated on a two-point scale (P/R = poor to reasonable, G/O = good to optimal). …”
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One-pot green synthesis of BSA-capped O-CQDs as an effective fluorescent sensing platform for sensitive and selective detection of promethazine drug by S. Viji, A. Dinesh, K. Radhakrishnan, L. Srimathi Priya, C. Sivasankari, Madhappan Santhamoorthy, Manikandan Ayyar, V. Mohanavel, Mohamed Hashem, Hassan Fouad, G. Ramachandran, S. Santhoshkumar

“…Obtained results show that BSA-O-CQDs had higher specificity for promethazine Furthermore, their ability to resolve non-specific binding was assessed under simulated physiological backgrounds, demonstrating their promise for robust biosensing applications. …”
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Teknologi Irigasi Cerdas pada Sistem Irigasi Drip dengan Algoritma Ant Colony Optimization by Abdul Haris, Nabilla Anggraini, Hengki Sikumbang

“…Existing research only focuses on the Open / Close solenoid valve, meanwhile this research   uses the Ant Colony Optimiation (ACO) algorithm to control the valve and provide the tracking ability to determine the area that needs irrigation the most. …”
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Tomographic features of lung damage associate with D-Dimer levels and further clinical outcome in patients with acute respiratory distress syndrome due to COVID-19 by Juan Antonio Suárez-Cuenca, José Fernando Flores-Zaleta, Leslie Andrea Corona-Rojas, Pablo Guzmán-Rullán, Luis Alfonso Camacho-Barajas, Uzziel Aguilera-Ontiveros, Alberto Melchor-López, Alejandro González-Mora, Perla Marlene Guzmán-Ramírez, Janicia Rodríguez-Solis

“…Conclusion Tomographic extent of lung involvement and the pattern of lung injury are related with coagulopathy severity markers like D-Dimer, and own prognostic clinical ability in ARDS.…”
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Hydrogen bond interactions of coumarin-153 in molecular solvents: molecular dynamics and principal component analysis by Goloviznina, Kateryna, Dudariev, Dmytro, Miannay, François-Alexandre,  Kalugin, Oleg, Koverga, Volodymyr, Takamuku, Toshiyuki, Vitale, Raffaele, Idrissi, Abdenacer

“…Hydrogen bond interactions significantly affect the coumarin-153’s (C153) photophysics, including its ability to act as a donor of weak hydrogen bonds via its 14 C–H bonds and as an acceptor via its O atoms in the ester and the carbonyl groups, as well as via its F atom in the trifluoromethyl group. …”
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Presenting a Leadership Empowerment Model through Sense-making by Using the Cognitive and Behavioral Scripts by Hamid Zare, Aliasghar Pourezzat, Hasan Zareei Matin, Arezoo Salmani

“…Leadership is extensively defined as the ability to significantly alter the values, beliefs, and attitudes of people, primarily exerting this influence through persuasive and strategic interactions. …”
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Analyzing the Influence of Managerial Traits and Financial Strategies on Corporate Risk-taking in the Tehran Stock Exchange by Gholamreza Karami, Ali Asghari

“…ResultsThe results obtained from the first hypothesis showed that the characteristics of management (management ability, management overconfidence, political connections, and power of the CEO) reduce the company's risk-taking. …”
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Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps by Colinet, Dominique, Cavigliasso, Fanny, Leobold, Matthieu, Pichon, Apolline, Urbach, Serge, Cazes, Dominique, Poullet, Marine, Belghazi, Maya, Volkoff, Anne-Nathalie, Drezen, Jean-Michel, Gatti, Jean-Luc, Poirié, Marylène

“…We also show that both RhoGAP families have undergone evolution under positive selection and that almost all of these RhoGAPs lost their GAP activity and GTPase binding ability due to substitutions in key amino acids. These results suggest an accelerated evolution and functional diversification of these vesicle-associated RhoGAPs in the two phylogenetically distant parasitoid species. …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…While previous studies on canine DLBCL (cDLBCL) have significantly advanced our understanding of the disease, the majority of this research has relied on whole-exome sequencing, which is limited in its ability to detect copy number aberrations and other genomic changes beyond coding regions. …”
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Silent magnetic resonance angiography diagnostic value of intracranial unruptured aneurysms by Bin Lv, Tingyang Zhang, Ning Wang, Lu Liu, Mingyu Li, Meng Li, Mingguang Sun, Xiao Zang, Xinfeng Liu, Rongju Zhang, Xiangyu Cao, Zhihua Du, Jun Wang, Jinhao Lyu, Xueyang Wang, Qi Duan, Fangfang Guo, Xin Lou, Chenglin Tian

“…In conclusion, S-MRA and 3D-TOF MRA did not significantly differ in aneurysm detection ability. For the detection of aneurysm with dauthger sacs indicators, the sensitivity is also higher.…”
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Designing a Conceptual model for Evaluating the Performance of Software Developers in Fintech Organizations by Hassan Javadi, Fereshteh Amin

“…These sub-themes, listed in order of priority, include teamwork, quality of produced software, customer satisfaction, documentation skills, participation in knowledge sharing, commitment to scheduling, mastery of production tools, participation in goal realization, compliance with organizational regulations, adherence to technical standards, problem-solving ability, and frequency of software rewriting. These criteria were further classified into three overarching dimensions: technical, individual, and organizational. …”
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Nutritional and antioxidative characterization, antimicrobial and sensorial stability of flaxseed powder supplemented mutton patties by Raheel Suleman, Hira Choudhary, Muhammad Waseem, Jaza Maqbl Alshammari, Muhammad Muzamil, Huan Liu, Tariq Ismail, Muhammad Ammar Khan, Muhammad Qamar, Crossby Osei Tutu

“…Conclusively, owing to better potential of FP in improving the nutritional and microbial quality of mutton patties, the study further suggests its ability to act as a novel functional ingredient of choice in shelf-life extension of other food products.…”
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How Organizational Citizenship Behavior Stimulant: Transformational Leadership Identification Model Approaches by Mochamad Soelton, Agus Arijanto, Yanto Ramli, Suprapto, Irmayunita, Subur Karyatun, Anees Janee Ali

“…Conclusion: Leaders who have the ability to lead with a good transformational style will create an atmosphere of OCB among most of their employees, including employee work engagement will increase if the organization has a transformational leadership style. …”
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PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports by Javier Corvi, Nicolás Díaz-Roussel, José M. Fernández, Francesco Ronzano, Emilio Centeno, Pablo Accuosto, Celine Ibrahim, Shoji Asakura, Frank Bringezu, Mirjam Fröhlicher, Annika Kreuchwig, Yoko Nogami, Jeong Rih, Raul Rodriguez-Esteban, Nicolas Sajot, Joerg Wichard, Heng-Yi Michael Wu, Philip Drew, Thomas Steger-Hartmann, Alfonso Valencia, Laura I. Furlong, Salvador Capella-Gutierrez

“…Text mining technologies have the ability to automatically extract, analyse and aggregate such information, providing valuable new insights into the drug discovery and development process. …”
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MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism by Ni Mo, Chuyang Tai, Yang Yang, Cong Ling, Baoyu Zhang, Lei Wei, Cian Yao, Hui Wang, Chuan Chen

“…HUVEC activity and mitochondrial structure and function were detected to explore the ability of MT2A to alleviate CPO-induced damage. Finally, a rat model of 2-vessel occlusion plus encephalo-myo-synangiosis (2VO + EMS) with CPO was established to test the proangiogenic effect of MT2A through the copper–mitochondria regulatory mechanism in chronically ischemic brains. …”
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Chemopreventative potential of Salsola tuberculatiformis Botch and Compound A in the differential regulation of IL-1Ra:IL-1α in UVB exposed skin keratinocytes by T. Magcwebeba, L. McEvoy, S. Hayward, T. Tait, J.L Quanson, L. Kelbe, WCA Gelderblom, M. Lilly, A.C Swart, P. Swart

“…Background: Salsola tuberculatiformis Botsch, commonly known as Gannabos, is a Namibian shrub known for its contraceptive properties in rats and its ability to modulate adrenal steroidogenesis both in vitro and in vivo. …”
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The interplay between persistent pathogen infections with tumor microenvironment and immunotherapy in cancer by Si Chen, Caihong Yao, Na Tian, Chunying Zhang, Yuemei Chen, Xuting Wang, Yue Jiang, Tonghao Zhang, Tingting Zeng, Yali Song

“…This interference impairs the body's ability to eliminate these microorganisms promptly, allowing them to persist by evading immune defenses. …”
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