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    Effect of glucagon-like peptide-1 receptor agonists in osteoarthritis: A systematic review of pre-clinical and human studies by Jacinta Cheng, Tia Solomon, Mahnuma Estee, Flavia M. Cicuttini, Yuan Z. Lim

    Published 2025-03-01
    “…Pre-clinical studies consistently demonstrated favourable chondroprotective and immunomodulatory effects of GLP-1A in osteoarthritis, with a dose-dependent effect, primarily driven by inhibition of NF-κB pathway. Limited human studies supported these findings in osteoarthritis. …”
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