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Multiple low-dose radiation ameliorates type-2 diabetes mellitus via gut microbiota modulation to activate TLR4/MyD88/NF-κB pathway
Published 2025-02-01“…Furthermore, the inflammatory effects activated by TLR4/MyD88/NF-κB pathways in T2DM were ameliorated by LDR. Conclusion These results suggest that LDR may exert a beneficial role in T2DM by modulating gut microbiota and metabolites, especially in TLR4/MyD88/NF-κB pathway.…”
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Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea
Published 2025-02-01Subjects: Get full text
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A comprehensive analysis of percutaneous liver biopsy characteristics and pathological manifestations in a large patient cohort (2009–2024)
Published 2025-02-01Subjects: Get full text
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Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women
Published 2025-02-01Subjects: Get full text
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Circulating miR-574–5p shows diagnostic and prognostic significance and regulates oxygen-glucose deprivation (OGD)-induced inflammatory activation of microglia by targeting ATP2B2
Published 2025-02-01“…Among predicted targets, ATP2B2 was upregulated in ischemic stroke and showed a negative correlation with miR-574–5p. miR-574–5p negatively regulated ATP2B2 in OGD-induced microglia, and the overexpression of ATP2B2 reversed the protective effect of miR-574–5p. …”
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Astaxanthin relieves HT22 cells from LPS-induced inflammation and apoptosis by inhibiting oxygen species and regulating the TLR4/MyD88/NFκB signaling pathway
Published 2025-02-01“…In summary, we demonstrated that ATX can alleviate LPS-induced ROS accumulation, inflammation, and apoptosis, with its anti-inflammatory effects closely linked to the TLR4/MyD88/NFκB signaling pathway.…”
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VGG-16, VGG-16 With Random Forest, Resnet50 With SVM, and EfficientNetB0 With XGBoost-Enhancing Bone Fracture Classification in X-Ray Using Deep Learning Models
Published 2025-01-01“…This paper makes a comparison of different machine learning models on classifying bone fractures: VGG-16, VGG-16 with Random Forest, ResNet-50 with Support Vector Machine, and EfficientNetB0 with XGBoost. Model performances were evaluated with respect to parameters of precision, recalls, and F1-scores. …”
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