PCSK9 affects vascular senescence through the SIRT1 pathway by Yuqin Wang, Shaoqing Cao, Zhangyu Wang, Chengsi Li, Jiangping Ye, Yehong Liu, Tianhui Jin, Yuting Zhou, Wentao Su, Gangjun Zong

“…Age is an independent risk factor for atherosclerotic cardiovascular disease that increases the susceptibility of older adults to vascular intimal thickening, endothelial dysfunction, and thrombosis. …”
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Global burden of ischemic heart disease in older adult populations linked to non-optimal temperatures: past (1990–2021) and future (2022–2050) analysis by Lihui Liu, Lihui Liu, Yisong He, Yisong He, Gang Huang, Yangxi Zeng, Yangxi Zeng, Jiaan Lu, Ru He, Haiqing Chen, Yuheng Gu, Qingwen Hu, Bin Liao, Bin Liao, Juyi Wan, Juyi Wan

“…Extreme temperatures, especially very low and very high temperatures, are known to exacerbate cardiovascular disease burden. With the ongoing global climate change, understanding the impact of non-optimal temperatures on IHD burden becomes increasingly important, especially in vulnerable populations such as the older adult.MethodsThis study used data from the Global Burden of Disease Study 2021 (GBD 2021) to analyze the spatiotemporal trends of low and high temperatures on IHD burden in the older adult population (aged 60 and above) from 1990 to 2021. …”
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Optimasi Algoritma Naive Bayes dengan Diskritisasi K-Means pada Diagnosis Penyakit Jantung by Nafa Fajriati, Budi Prasetiyo

“…Abstract   Ischemic heart disease is a type of cardiovascular disease with a large number of sufferers and is the leading cause of death in the world. …”
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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

“…Background Metformin (Met) is the first-line treatment for type 2 diabetes mellitus and plays an effective role in treating various diseases, such as cardiovascular disease, neurodegenerative disease, cancer, and aging. …”
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Evaluating the World Health Organization’s Hearts Model for Hypertension and Diabetes Management: A Pilot Implementation Study in Guatemala by Irmgardt Alicia Wellmann, Luis Fernando Ayala, Taryn M. Valley, Vilma Irazola, Mark D. Huffman, Michele Heisler, Peter Rohloff, Rocío Donis, Eduardo Palacios, Manuel Ramírez-Zea, David Flood

“…Background: The World Health Organization HEARTS Technical Package is a widely implemented global initiative to improve the primary care management of cardiovascular disease risk factors. The study’s objective is to report outcomes from a pilot implementation trial of integrated hypertension and diabetes management based on the HEARTS model in Guatemala. …”
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Association of blood cadmium and physical activity with mortality: A prospective cohort study by Yilin Chen, Cien Zhen, Lin Zeng, Hongliang Feng, Jinyu Wang, Qi Yong H. Ai, Sizhi Ai, Jihui Zhang, Yannis Yan Liang, Huachen Xue, Yujing Zhou

“…During a median follow-up of 7.6 years, a total of 2002 (9.89 %) all-cause deaths occurred, of which 581 (2.87 %) participants were due to cardiovascular disease (CVD) and 498 (2.46 %) died of cancer. …”
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Association between echocardiographic parameters of cardiac structure and function and mild cognitive impairment by Kai Zhang, Xiaoxia Liu, Siyu Huang, Xinrui Liu, Meiqi Zhao, Chao Xue, Shijun Xia, Jianzeng Dong, Yu Kong, Changsheng Ma

“…Abstract Background Cardiovascular diseases (CVDs) marked with cardiac morphological or hemodynamical abnormalities are associated with mild cognitive impairment (MCI). …”
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Cardiac repair using regenerating neonatal heart tissue-derived extracellular vesicles by Hanjing Li, Yining Liu, Yuqing Lin, Sijia Li, Chenlu Liu, Ao Cai, Wei Li, Wanyu Zhang, Xinlu Gao, Zhongyu Ren, Haoyu Ji, Yang Yu, Xiuxiu Wang, Wenya Ma, Ning Wang, Dan Zhao, Tianlong Li, Yu Liu, Benzhi Cai

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Editorial: Immunity and pulmonary vascular diseases: challenges, advances and future perspectives by Qi Jin, Qi Jin, Daxin Zhou, Daxin Zhou, Zhihong Liu, Djuro Kosanovic

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Heart transplantation in South America: Risk factors, challenges, and opportunities by Renzo Y. Loyaga-Rendon, MD, PhD, MSPH, Deepak Acharya, MD, MSPH

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L-shaped association between ankle-brachial index and coronary heart disease in Chinese adults with hypertension by Wei Zhou, Yumeng Shi, Chao Yu, Tao Wang, Lingjuan Zhu, Huihui Bao, Xiaoshu Cheng

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Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation by Vedran Velagic, Vedran Pasara, Ivan Prepolec, Andrija Nekic, Zvonimir Katic, Davor Milicic

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Physiological variables associated with the development of acute mountain sickness at the South Pole by Paul J Anderson, Bruce D Johnson, Michael F Harrison, Andrew D Miller, Kathy A O'Malley, Maile L Richert, Jacob B Johnson

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New Approaches for Preeclampsia: Review of the Literature by Emel Ebru Özçimen

“…Hypertension in pregnancy carries risk for future in cardiovascular diseases.…”
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Clinical characteristics of patients with coronary artery disease by smoking status by Olga V. Nakhratova, Daria P. Tsygankova, Joseph M. Tsenter, Evgeny D. Bazdyrev

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Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional Study by Ali Hamidi Madani, Fardin Mirbolouk, Mona Naghshbandi, Tolou Hasandokht, Mahboobe Gholipour, Mohammad Sajjad Zabihi, Mohammad Hamidi Madani

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Sphingolipid metabolites involved in the pathogenesis of atherosclerosis: perspectives on sphingolipids in atherosclerosis by Fufangyu Zhao, Mingyan Shao, Mingrui Li, Tianxing Li, Yanfei Zheng, Wenlong Sun, Cheng Ni, Lingru Li

“…Abstract Atherosclerosis, with its complex pathogenesis, is a leading underlying cause of many cardiovascular diseases, which are increasingly prevalent in the population. …”
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Medicinal Potential of Pine Trees: A Brief Review Focusing on Three Species by Qinsong Li, Qiyu Li, Anping Wang, Wenxuan Quan

“…The wide range of pharmacological activities of these bioactive components is helpful for the treatment of cardiovascular diseases, inflammatory diseases, tumors, and other diseases. …”
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Citrus Flavonoid Effects on Obesity by Yu Wang, Laura E. Reuss

“…Obesity, a chronic disease that increases the risk for a myriad of diseases including diabetes, hypertension, cardiovascular diseases, as well as certain types of cancers, results from a persistent excess of energy intake versus energy expenditure and is characterized by an increase in both adipose cell size and number. …”
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Experience of enrollment and management of the Waiting list for liver transplantation at hepatological center by Ye. N. Bessonova, O. A. Stroganova, Yu. A. Glazyrina, I. A. Kornilova

“…Most often alcoholism (21,6%) and cardiovascular diseases (14,0%) prevented inclusion to the Waiting list of potential recipient. …”
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