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3001
Prevalence of behavioral risk factors among Ukrainians during war amid existing stress factors
Published 2024-12-01“… Background: Military conflicts and associated stress often lead to lifestyle changes. Unhealthy behaviors play a pivotal role in the development of cardiovascular risk factors and are potentially reversible. …”
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3002
Climate variability, population growth, and globalization impacting food security in Pakistan
Published 2025-02-01“…Abstract Global hunger has increased recently, returning to levels observed a decade ago. Climate change is identified as a key factor contributing to these increases and is a significant cause of severe food crises. …”
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3003
Microscale insight into the proton concentration during electrolytic reaction via an optical microfiber: potential for microcurrent monitoring by a dielectric probe
Published 2025-02-01“…By sensing the refractive index variation surrounding the sensor induced by the interaction between local proton concentration changes and oxidizer-treated microfiber surface through the evanescent field, this sensing mechanism effectively avoids the interference of the electromagnetic material on the performance of the tested system. …”
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3004
Epidemiological trends and predictions of urinary tract infections in the global burden of disease study 2021
Published 2025-02-01“…The estimated annual percentage change was used to depict temporal trends, whereas Pearson correlation analysis explore its correlation with the human development index (HDI), the SDI, and age-standardised rates (ASRs). …”
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3005
Dietary Total Antioxidant Capacity and Gastric Cancer: A Case-Control Study
Published 2025-02-01“…This association did not change after adjustment for body mass index, education, energy intake, smoking, and Helicobacter pylori infection (0.55; 95% CI: 0.31-0.99). …”
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3006
A review of metabolic calorimetric applications in plant stress, waste management, and diagnostics
Published 2024-09-01“…Biologically exothermic reactions—which involve biotransformation mechanisms during composting, wastewater reuse, and organic sludge stability as physiochemical attributes of solid and liquid wastes via changes in heat release—influence plant dynamic stress variables. …”
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3007
Standard reference values of the postural control in healthy young female adults in Germany: an observational study
Published 2019-06-01“…The comparison of patient data with standard values can highlight deteriorations or changes in postural control and thus indicate, for example, an increased risk of falling. …”
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3008
Ultrasound diagnostics of traumatic pancreatitis at combined trauma
Published 2014-08-01“…Dynamic US-study allows to reveal in due time signs of acute pancreatitis as well as complications. Pancreatic changes may be considered as developing dysfunction of the organ at multiorgan failure.…”
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3009
Helicobacter pylori promotes intestinal flora imbalance and hepatic metabolic disorders under arsenic stress
Published 2025-01-01“…Further analysis revealed significant correlations between changes in the intestinal flora and alterations in liver metabolic profiles. …”
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3010
Integration of transcriptomics and metabolomics data revealed role of insulin resistant SNW1 gene in the pathophysiology of gestational diabetes
Published 2025-02-01“…Transcriptomic studies identified SNW1 as the most sensitive and specific biomarker, significantly up-regulated in GDM (fold change = 1.09; p < 0.001). Metabolomic studies indicated significantly elevated gluconeogenesis in GDM, evidenced by decreased levels of alanine and increased levels of pyruvate and glucose compared to controls. siRNA-mediated knockdown of SNW1 in PANC1 cells resulted in significant down-regulation of alanine aminotransferase (ALT/GPT) and insulin receptor substrate (IRS1), while glucose transporters (GLUT2/GLUT4) and insulin (INS) were significantly up-regulated at both mRNA and protein levels. …”
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3011
Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer
Published 2025-02-01“…Western blot and immunofluorescence were used to explore the potential molecular changes. BU can precisely regulate c-Myc expression by targeting SRC-3 in chemoresistant cells was confirmed by Western blot. …”
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3012
Detection of serum composition in pediatric inflammatory multisystem syndrome associated with SARS-CoV-2 and the response for the treatment by FTIR
Published 2025-02-01“…In this paper, we propose Fourier Transform InfraRed spectrometry (FTIR) to identify chemical changes in blood serum of children induced by PIMS and caused by subsequent treatment of the syndrome. …”
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3013
An exploratory study to evaluate efficacy and safety of frequent Transcutaneous Electrical Stimulation for Leber Hereditary Optic Neuropathy
Published 2025-02-01“…The secondary outcomes included changes in visual field; LogMAR; critical flicker frequency; and inner retinal thickness. …”
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3014
Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern EuropeansResearch in context
Published 2025-03-01“…Interpretation: Given the dramatic changes from hunting and gathering to agriculture during the Neolithic, AF might have been exposed to selective pressures from a pro-inflammatory lifestyle and diet. …”
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3015
Precision livestock farming applied to the dairy sector: 50 years of history with a text mining and topic analysis approach
Published 2025-03-01“…The global dairy industry has been revolutionized by advancements in genetics, milking technology, nutrition, and farm management, leading to increased milk production per cow and a substantial rise in total annual milk output. These changes have pushed the dairy industry toward a more technological approach that, with the aid of precision livestock farming (PLF), has maximized the production per cow. …”
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3016
Radiographic Features of Spinal Meningioma and Schwannoma: A Novel Specific Feature―Ginkgo Leaf Sign
Published 2025-01-01“…For schwannomas, specific findings included a lobule shape (sensitivity 25%, specificity 95%), dumbbell shape (sensitivity 54%, specificity 100%), and cystic changes (sensitivity 54%, specificity 97%). Conclusions: GLS may be a specific radiological feature for meningiomas and can aid in diagnosis when combined with DTS. …”
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3017
Digital twins as global learning health and disease models for preventive and personalized medicine
Published 2025-02-01“…However, widespread implementation faces several challenges: (1) characterizing dynamic molecular changes across multiple biological scales; (2) developing computational methods to integrate data into DTs; (3) prioritizing disease mechanisms and therapeutic targets; (4) creating interoperable DT systems that can learn from each other; (5) designing user-friendly interfaces for patients and clinicians; (6) scaling DT technology globally for equitable healthcare access; (7) addressing ethical, regulatory, and financial considerations. …”
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3018
Experimental study on the collapse behavior of cavitation bubbles under low ambient pressure conditions
Published 2025-03-01“…Experimental results show that as ambient pressure decreases, the pressure difference between the interior and exterior of bubbles, induced by identical energy, changes during their evolution. Consequently, the bubbles exhibit a gradual increase in maximum radius and an extended evolution period within an unbounded environment. …”
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3019
Genetically edited human placental organoids cast new light on the role of ACE2
Published 2025-02-01“…Placental organoids with the ACE2 rs2074192 TT genotype had significantly higher expression of ACE2 mRNA and ACE2 protein with elevated ACE2:ACE expression ratio and no change in ACE protein. Despite increased expression of ACE2 protein, ACE2 enzyme activity was significantly decreased in ACE2 rs2074192 TT placental organoids. …”
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3020
Study on the regulation of tea polyphenols on the structure and gel properties of myofibrillar protein from Neosalanx taihuensis
Published 2025-01-01“…Additionally, TP addition induced changes in the MP structure, with further exposure of hydrophobic regions. …”
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