Evaluation of the digital diabetes prevention programme pilot: uncontrolled mixed-methods study protocol by William Henley, Elizabeth Murray, Kerry Daff, Anthi Lavida, Jenny Irwin, Jonathan Valabhji

“…Quantitative data will be analysed descriptively and using generalised linear models to determine whether changes in outcomes are associated with demographic and intervention factors. …”
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Mechanisms and regulatory pathways of recessive land use transition by TAN Lin, CHEN Lan

“…These three forms are closely interconnected and interact with each other. (2) Implicit land use transition is the process of significant and fundamental changes in efficiency, functional, and power forms. …”
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Enhancing climate resilience: A data-driven north rift weather prediction system for real-time forecasting and agricultural decision support by John W. Makokha, Peter W. Barasa, Geoffrey W. Khamala

“…Moreover, its integration into larger decision support systems allows for proactive interventions to mitigate land degradation and climate change stressors. This study emphasizes the importance of sustainable land-use practices and climate adaptation strategies to preserve vegetation health and manage ecosystem vulnerabilities effectively in the wake of regional climate change with the North Rift region most affected.…”
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Investigating the Implications of COVID-19 on PM2.5 in Pakistan by Hassaan Sipra, Faheem Aslam, Jabir Hussain Syed, Tahir Mumtaz Awan

“…Drastic, significant change is found on the efficiency of air quality in Lahore before and during COVID-19 periods. …”
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Transition characteristics and driving mechanisms of different types of rural settlements in plain agricultural areas by QU Yanbo, HE Xinhan, DONG Xiaozhen, LIU Chunqiang, YANG Yong, LI Yuanchao

“…The Xinli Village of the preservation-improvement type retains the traditional development mode of ordinary villages, with weak changes in various morphologies, showing a low level of rural settlements transformation. (2) The driving mechanisms of four types of rural settlements transition are jointly promoted by common and distinctive factors. …”
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Effect of cubebin against streptozotocin-induced diabetic nephropathy rats via inhibition TNF-α/NF-κB/TGF-β: in vivo and in silico study by Rahamat Unissa Syed, Sivakumar S. Moni, Weiam Hussein, Taghreed Mohammad Saad Alhaidan, Sondos Mohammed Y. Abumilha, Lama Khalid Alnahdi, Ling Shing Wong, Vetriselvan Subramaniyan, Vinoth Kumarasamy

“…Molecular docking [(PDB ID: TNF-α (7JRA), NF-κB (1SVC), TGF-β1 (3TZM)] and dynamic simulation (MDS) were also performed with the selected target. STZ-induced DN was changes in these parameters. In contrast, DN + cubebin at 10 and 20 mg/kg doses improved the biochemical parameters and histological changes. …”
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The Result of Timely Therapy for Whipple's Disease: a Clinical Case by S. N. Mekhtiev, O. A. Mekhtieva, E. Yu. Kalinina, V. E. Karev, A. V. Vanyan, O. M. Berko

“…The diagnosis was established on the basis of morphological changes in biopsy samples of the postbulbar part of the duodenum. …”
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Effects of removing reimbursement restrictions on targeted therapy accessibility for non-small cell lung cancer treatment in Taiwan: an interrupted time series study by Jason C Hsu, Chen-Fang Wei, Szu-Chun Yang

“…The average time to prescription reduced by 65.84% and 41.59% following coverage of erlotinib by insurance and gefitinib/erlotinib as second-line treatments in 2007–2008 and following gefitinib as the first-line treatment in 2011.Conclusions The changes in reimbursement policies had a significant impact on the accessibility of targeted therapies for NSCLC treatment. …”
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Gender-transformative HIV and SRHR programme approaches for adolescents and young people: a realist review to inform policy and programmes by Isolde Birdthistle, Annabelle Gourlay, Sagri Singh, Damilola Walker, Migena Mata

“…However, most interventions prioritise individual rather than structural change; impeding their ‘gender transformative’ potential.…”
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Pathogenesis of Disorders of the Motor Function of the Large Intestine in Functional Constipation by M. M. Galagudza, Yu. P. Uspensky, Yu. A. Fominykh, D. Yu. Butko

“…A key role in the FC development belongs to a decrease in the pool of interstitial cells, which play the role of an intestinal pacemaker, due to slowing of their self-renewal. FC-associated changes in the enteric nervous system include a relative excess of the contribution of inhibitory influences and a decrease in the activity of cholinergic and serotonergic neurons that stimulate intestinal motility. …”
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Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions. by Karen Campos-León, Jack Ferguson, Thomas Günther, C David Wood, Steven W Wingett, Selin Pekel, Christy S Varghese, Leanne S Jones, Joanne D Stockton, Csilla Várnai, Michelle J West, Andrew Beggs, Adam Grundhoff, Boris Noyvert, Sally Roberts, Joanna L Parish

“…Upon infection, human papillomavirus (HPV) manipulates host cell gene expression to create an environment that is supportive of a productive and persistent infection. The virus-induced changes to the host cell's transcriptome are thought to contribute to carcinogenesis. …”
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Review of the Urban Carbon Flux and Energy Balance Based on the Eddy Covariance Technique by Yuxuan Li, Xinli Cai, Mingjun Li, Zhen Jiang, Feifei Tang, Shaojie Zhang, Taotao Shui, Shuguang Zhu

“…Abstract In recent years, notable climate change has prompted more scholars to give more attention to urban climate development. …”
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Trends, gender, and racial disparities in patients with mortality due to paroxysmal tachycardia: A nationwide analysis from 1999-2020. by Aman Goyal, Humza Saeed, Saif Yamin, Abdullah, Wania Sultan, Muhammad Khubaib Arshad, Samia Aziz Sulaiman, Mah I Kan Changez, Gauranga Mahalwar

“…Age-adjusted mortality rates (AAMRs) and annual percent changes (APC) were calculated by year, gender, age group, race/ethnicity, geographic location, and urbanization status. …”
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Impact of Ramadan Intermittent Fasting on Salivary pH, Flow Rate, and Electrolyte Levels in Healthy Adult Men by Sinda Yacoub, Mehdi Khemiss, Amira Besbes, Helmi Ben Saad

“…To conclude, RIF decreased salivary calcium, increased salivary pH, and did not significantly affect potassium, sodium, chloride, or phosphate. The pH change, although statistically significant, was clinically insignificant, as values remained normal. …”
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The Role of Using Motorized Diamond Burr Polisher Instrument in Minimizing the Recurrent Rate of Pterygium Excision by Sakar Abdulkarim Nidhamalddin

“…Corneal scar happens in only 1(2.2%) case of group A while in 11(24.4%) cases in group B, Corneal scar was statistically significant. In both groups the change of BCVA was significant but the visual change was more significant in group A in compare to group B. …”
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Climate-smart livestock nutrition in semi-arid Southern African agricultural systems by Felix Fushai, Teedzai Chitura, Oyegunle Emmanuel Oke

“…Climate change is disrupting the semi-arid agricultural systems in Southern Africa, where livestock is crucial to food security and livelihoods. …”
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First-year Class Instills Confidence in Nontechnical Skills for Collegiate Success by Anna Levina, Katy Guthrie, Leah Cook, Marvin Pritts

“…Assessing these skills with standard fact-based testing methods is not effective, so we assessed change in confidence during the semester, allowing students to self-assess their own learning. …”
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Estimating the Health-Related Quality of Life Benefit of Prophylactic Treatment for COVID-19 in Immunocompromised People: A Multimethod Valuation Study by Katy Gallop, Rebekah Hall, Michael Watt, Daniel Squirrell, Neil Branscombe, Sofie Arnetop, Andrew Lloyd

“…PrEP would lead to behavior changes for 75% (30/40) of individuals with IC conditions and an emotional benefit for 93% (37/40) of individuals with IC conditions. …”
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Concrete Production and Curing with Recycled Wastewater: A Review on the Current State of Knowledge and Practice by Tobby Michael, Agwe, Tibenderana, Philip, Twesigye-Omwe, Moses N, Abdulkadir, Sholagberu Taofeeq

“…These include increasing population, rapid urbanization, industrialization, changed land pattern usage and land cover, change in the overall ecological system, and increased temperature and unscientific compromises in the extraction of water are at alarming threshold putting pressure on the finite available freshwater resources. …”
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The Role of Non-Governmental Organisations (NGOs) on the Socio¬economic Transformation of Rural Areas in Nyarusiza Sub-County Kisoro District. by Izabayo, Joan

“…The study concludes that the NGOs in the Nyarusiza sub-county, Kisoro district, like to manifest themselves as advocates of social change. The priority for achieving effective social change is to eliminate all forms of discrimination in society, and the empowerment of women is the first step. …”
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