Did selective kinase inhibitors change the management of patients with radioiodine-refractory thyroid cancer? by Tommaso Porcelli, Cristina Luongo, Anna Cerbone, Carmine Di Luccio, Mariantonia Nacchio, Maria Angela De Stefano, Martin Schlumberger, Domenico Salvatore

“…Patients and methods: We extracted data from 69 consecutive patients referred to Federico II University Hospital from September 2016 to September 2024, among whom 44 patients were treated with TKIs as first-line treatment and outside any clinical trial, and form the basis of this report. Results: Thirty-one (71%) patients were treated with the antiangiogenesis inhibitor lenvatinib and 13 (29%) were treated with selective tyrosine kinase inhibitors (s-TKIs). …”
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Effectiveness of Single-Tablet Combination Therapy in Improving Adherence and Persistence and the Relation to Clinical and Economic Outcomes by Carly J. Paoli, Jörg Linder, Khushboo Gurjar, Deepika Thakur, Julie Wyckmans, Stacy Grieve

“…This may be due to clinical trial procedures aimed at maximizing adherence and HRQoL measures that are not designed to evaluate drug administration. …”
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Effects of balanced opioid-free anesthesia on post-operative nausea and vomiting in patients undergoing video-assisted thoracic surgery: a randomized trial by Xiang Yan, Chen Liang, Jia Jiang, Ying Ji, An-Shi Wu, Chang-Wei Wei

“…This anesthetic regimen has shown good feasibility without significantly increasing the patient’s pain score and complications. Clinical trial registration number Clinicaltrials.gov, Identifier: NCT05411159. …”
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Transcranial direct current stimulation combined with physical exercise in rotator cuff tendinopathy: a protocol for a blinded randomised controlled trial by César Augusto Medeiros Silva, Clécio Gabriel de Souza, Vinicius Batista Lima, Hannely Beatriz Menezes Cosme, Romário Nóbrega Santos Fonseca, Fuad Ahmad Hazime, Rodrigo Scattone da Silva, Rodrigo Pegado de Abreu Freitas

“…The results will be published later in peer-reviewed journals and scientific events.Trial registration number The Brazilian Registry of Clinical Trials (RBR-59xmv6s); Results.…”
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Efficacy of continuous intravenous infusion of lidocaine on postoperative sore throat after laryngeal mask insertion: a randomized controlled trial by Jianxin Jiang, Jimin Wu, Shuqi Shi, Xiaoli Dong, Jiaxiang Yin, Yini Wu

“…Trial Registration Chinese Clinical Trial Registry (ChiCTR2300070339,04/10/2023).…”
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Network Meta-Analysis of Once Weekly Selinexor-Bortezomib-Dexamethasone in Previously Treated Multiple Myeloma by Michael Dolph, Gabriel Tremblay, Adrienne M Gilligan, Hoyee Leong

“…**Methods**: Ovid was systematically searched for phase 2-3 randomized clinical trials (RCTs) in MM that assessed progression-free survival (PFS), overall survival (OS) and overall response rates (ORR). …”
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Molecular assessment of NMDAR subunits and neuronal apoptosis in the trigeminal ganglion in a model of male migraine-induced rats following Moringa oleifera alcoholic extract admin... by Ahmad Vafaeian, Ali Vafaei, Mohammad Reza Parvizi, Mohsen Chamanara, Mojgan Mehriardestani, Yasaman Hosseini

“…Conclusions Moringa oleifera extract appears to mitigate symptoms of migraine by inhibiting apoptosis, suggesting potential efficacy in migraine treatment; however, additional research investigating a wider range of pathways is necessary. Clinical trial number Not applicable.…”
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Insulin autoimmune syndrome in a 3-year-old boy: the youngest to date in China and a narrow review by Ming Cheng, Yuan Ding, Dongmei Wang, Chunxiu Gong

“…Elevated levels of IAAs and an inappropriate insulin to C-peptide molar ratio during an extended OGTT are critical indicators. Clinical Trial Number Not applicable.…”
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Protocol for evaluating the effects of integrating music with taekwondo training in children with autism spectrum disorder: A randomized controlled trial. by Clare C W Yu, Kam M Mok, Emma Mak, Chun T Au, Dorothy F Y Chan, Stanley Wu, Raymond C K Chung, Matthew C K Ip, Simpson W L Wong

“…ClinicalTrials.gov Identifier: NCT06277778. Registered on 15 February 2024.…”
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Hymecromone Efficacy in the Treatment of Biliary Pancreatitis by A. V. Okhlobystin, M. A. Tatarkina, O. Z. Okhlobystina, S. A. Budzinskiy, P. V. Pavlov, L. A. Labut

“…An open single-centre clinical trial included 30 patients with chronic pancreatitis (CP), which was diagnosed according to the Cambridge criteria. …”
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Home-based transcranial direct current stimulation paired with cognitive training to reduce fatigue in multiple sclerosis by Leigh Charvet, Judith D. Goldberg, Xiaochun Li, Pamela Best, Matthew Lustberg, Michael Shaw, Lana Zhovtis, Josef Gutman, Abhishek Datta, Marom Bikson, Giuseppina Pilloni, Lauren Krupp

“…We conducted a double-blind, sham-controlled, randomized clinical trial to compare active vs. low-dose (sham) tDCS paired with computer-based cognitive training, delivered as a home-based intervention, to reduce MS-related fatigue. …”
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A prospective model of the potential clinical and economic impact of cervical cancer screening supported by a mobile phone app. by Fredrick Chite Asirwa, Brian W Bresnahan, Faith Yego, Dana Duncan, James K Karichu, Louis P Garrison

“…The model is structured to simulate a three-visit pathway for HPV-based screening used in a clinical trial of the app and based on epidemiological data, clinical guideline-based workflow, and patient-based behavioral pathways. …”
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Impact of parathyroidectomy on inflammatory and cardiovascular risk parameters in primary hyperparathyroidism: a retrospective analysis by Nese Bulbul, Suat Sen, Fettah Acibucu

“…The study also suggests that these risk factors may be modifiable with timely surgical intervention. Clinical trial number Not applicable.…”
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The association between the dietary inflammatory index during pregnancy and risk of gestational diabetes: a prospective cohort study and a meta-analysis by Nastaran Payandeh, Hossein Shahinfar, Ahmad Jayedi, Majid Mirmohammadkhani, Alireza Emadi, Sakineh Shab-Bidar

“…The results need to be confirmed by larger cohort studies. Clinical trial number Not applicable.…”
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Clinical Effect of Teucrium polium Extract Ointment on Post Pilonidal Sinus Excision Wound Healing: A Randomized Controlled Trial by Reza Hosseinpour, Nuruddin Hosseini, Seyedeh Fatemeh Hekmatzadeh, Saadat Mehrabi, Hossein Sadeghi Mansourkhani, Marita Mohamadshahi

“…Methods: This randomized double-blind clinical trial was conducted from April 2021 to March 2022. …”
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The effectiveness of Transcranial Photobiomodulation therapy (tPBM) on reducing anxiety, depression, and opioid craving in patients undergoing methadone maintenance treatment: a do... by Helya Helali, Nastaran Samani, Faraj Tabeie, Shiva Eiliaei, Ali Kheradmand

“…Methods This randomized controlled clinical trial included two groups of substance-dependent patients undergoing MMT. …”
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Emotional exhaustion and turnover intentions among young ICU nurses: a model based on the job demands-resources theory by Xiaona Zhang, Haitao Huang, Songtao Zhao, Dan Li, Hua Du

“…Organizational justice and organizational-based self-esteem, as key work resources, moderated this relationship, mitigating the impact of emotional exhaustion on turnover intention. Clinical trial number Not applicable.…”
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Efficacy of linaclotide in combination with polyethylene glycol for bowel preparation in Chinese patients undergoing colonoscopy polypectomy: protocol for a randomised controlled t... by Jing Xu, Ping-ping Chen, Dong Chen, Hui-Ying Zhao, Xiao-Feng Cai, Xiao-Bin Wang, Chao-Xu Liu

“…This trial was registered on the Chinese Clinical Trial Registry with registration number ChiCTR2300075410…”
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Lactate/albumin ratio as a prognostic biomarker for in-hospital mortality in pediatric patients with necrotizing enterocolitis by Ban Li, Yuanzhi Chen, Zhen Yang, Xianglun Sun, Cheng Tian, Jingsi Liu, Lihua Yuan, Kanglin Dai

“…However, given the limitations of our research, more prospective studies are still needed in the future to test the predictive value of L/A ratio for the prognosis of NEC disease. Clinical trial number Not applicable.…”
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Does therapy with immunosuppressive drugs improve gastrointestinal symptoms in patients with systemic sclerosis? by Oliver Distler, Cosimo Bruni, Suzana Jordan, Carina Mihai, Muriel Elhai, Rucsandra Dobrota, Alexandru Garaiman, Mike Oliver Becker, Lea Stamm, Sherif Ismail, Norina Zampatti, Aurora Maria Tatu

“…We aimed to identify an association between immunosuppressive therapy and the the severity of GI symptoms, measured by the University of California at Los Angeles/Scleroderma Clinical Trial Consortium Gastro-Intestinal Tract instrument 2.0 (GIT).Methods We selected patients with SSc who had at least two visits (further referred to as ‘baseline’ and ‘follow-up’) with completed GITs, within an interval of 12±3 months. …”
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