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281
Potential pathogenic and protective genotypes and phenotypes of vitamin D binding protein in multiple sclerosis
Published 2025-02-01“…DNA regions covering the targeted mutations were amplified by PCR, sequenced by the Sanger method, and analyzed to determine GC genotypes and phenotypes. …”
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282
Microbiology /
Published 2005Table of Contents: “…The history and scope of microbiology -- The study of microbial structure: microscopy and specimen preparation -- Procaryotic cell structure and function -- Eucaryotic cell structure and function -- Microbial nutrition -- Microbial growth -- Control of microorganisms by physical and chemical agents -- Metabolism: energy, enzymes, and regulation -- Metabolism: energy release and conservation -- Metabolism: the use of energy in biosynthesis -- Genes: structure, replication, and mutation -- Genes: expression and regulation -- Microbial recombination and plasmids -- Recombinant DNA technology -- Microbial Genomics -- The viruses: introduction and general characteristics -- The viruses: bacteriophages -- The viruses: viruses of eucaryotes -- Microbial taxonomy -- The archaea -- Bacteria: the deinococci and nonproteobacteria gram negatives -- Bacteria: the proteobacteria -- Bacteria: the Low G 1 C gram positives -- Bacteria: the High G 1 C gram positivies -- The fungi (eumycota), slime molds, and water molds -- The algae -- The protozoa -- Microorganism interactions and microbial ecology -- Microorganisms in aquatic environments -- Microorganisms in terrestrial environments -- Normal microbiota and nonspecific host resistance -- Specific immunity -- Medical immunology -- Pathogenicity of microorganisms -- Antimicrobial chemotherapy -- Clinical microbiology -- The epidemiology of infectious disease -- Human diseases caused by viruses -- Human diseases caused by bacteria -- Human diseases causedd by fungi and protozoa -- Microbiology of food -- Industrial microbiology and biotechnology.…”
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283
Eye development under the control of SRp55/B52-mediated alternative splicing of eyeless.
Published 2007-02-01“…The long isoform has impaired ability to trigger formation of ectopic eyes and to bind efficiently Eyeless target DNA sequences in vitro. When over-produced in the eye imaginal disc, this isoform induces a small eye phenotype, whereas the isoform lacking the alternative exon triggers eye over-growth and strong disorganization. …”
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284
Northward expansion of the Critically Endangered Arabian leopard in Dhofar, Oman
“…However, a scat confirmed by DNA analysis in 2011 and camera-trap images from 2014 confirmed the presence of the leopard in this region. …”
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285
Engineering a bacterial toxin deaminase from the DYW-family into a novel cytosine base editor for plants and mammalian cells
Published 2025-02-01“…Abstract Base editors are precise editing tools that employ deaminases to modify target DNA bases. The DYW-family of cytosine deaminases is structurally and phylogenetically distinct and might be harnessed for genome editing tools. …”
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286
Sirtuin activators as an anti-aging intervention for longevity
Published 2025-01-01“…The mammalian sirtuins comprise seven members that have a role in energy metabolism, DNA repair, inflammation, cell survival, apoptosis, cellular senescence, oxidative stress, and mitochondrial production. …”
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287
AAV-based vectors for human diseases modeling in laboratory animals
Published 2025-02-01“…The genome of adeno-associated virus serves as a convenient expression cassette for delivering various DNA constructs into cells, and this method has proven effective in practice. …”
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288
On new spider species of the genus Episinus (Araneae, Theridiidae) from China and proposal of five species groups
Published 2025-02-01“…Detailed descriptions, photographs, hand drawings, DNA barcodes and a distribution map of the three new species are provided.…”
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289
A stratified two-stage tumor molecular profiling algorithm to identify clinically actionable molecular alterations in pancreatic cancer☆
Published 2025-03-01“…Actionable alterations were identified in 25/94 (26.6%) cases, including DNA damage response gene alterations, KRAS G12C and targetable drivers in KRAS wild type tumors. …”
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290
Oxidative stress in viral hepatitis
Published 2024-04-01“…This damage manifests as lipid peroxidation, DNA damage, and protein oxidation, which in turn promote hepatic inflammation, fibrosis, and hepatocellular carcinoma. …”
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291
CLASIFICACIÓN POR MÉTODOS MOLECULARES DE CEPAS DE Trypanosoma spp AISLADAS EN COLOMBIA Y EVALUACIÓN MORFOMÉTRICA
Published 2006-01-01“…Mediante el empleo de técnicas de PCR-RFLP se caracterizaron tres cepas de tripanosomas aisladas de bovinos de diferentes regiones de Colombia, a partir de ampliÀcaciones de la región 18S de la subunidad ribosomal del rDNA del parásito. Para el PCR inicial se emplearon los primers específicos nF2 y nR3, y sobre el producto obtenido de 756 pb se realizó un PCR semianidado con los primers NF2 y NR2 de la misma región. …”
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292
Representative Metagenomes of Mesophilic Biogas Reactor Across South Korea
Published 2025-02-01“…The present dataset addresses one of these gaps by providing comprehensive information on the metagenomes of five full-scale mesophilic biogas reactors in South Korea. From 110 GB of raw DNA sequences, 401 metagenome-assembled genomes (MAGs) were created, which include 42,301 annotated genes. …”
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293
Pulmonary fibrosis as the sole manifestation of anti-Ku antibody positivity in the absence of myositis: A case report
Published 2025-01-01“…Background: Anti-Ku antibodies are autoantibodies directed against the Ku protein complex involved in DNA repair. They are typically associated with overlap syndromes featuring polymyositis and systemic sclerosis. …”
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294
Egg Microinjection for the Ladybird Beetle Harmonia axyridis
Published 2024-12-01“…In this paper, we present a detailed protocol for microinjecting DNA, RNA, or protein solutions into fertilized eggs of the multicolored Asian ladybird beetle, Harmonia axyridis, under a stereomicroscope equipped with an injection apparatus. …”
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295
The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the Literature
Published 2015-04-01“…Following surgical procedures, high risk HPV DNA analysis using PCR were undertaken in both cases to investigate the possible role of HPV in synchronous malignancies. …”
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296
Mitochondrial Dysfunction as a Therapeutic Target in Diabetic Cardiomyopathy: Progress and Prospects
Published 2025-01-01“…Recent studies have highlighted the crucial roles of mitochondrial dysfunction in the pathogenesis of DCM, including aspects such as glucose-lipid metabolic disorder, oxidative stress damage, calcium regulation disorder, respiratory chain uncoupling, kinetic imbalance, and mitochondrial DNA damage. Increasing numbers of targets and drugs are being identified to ameliorate mitochondrial dysfunction and consequently slow DCM progression. …”
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297
Characteristics of the monkeypox virus isolate obtained from the first patient in Russia and its sensitivity to 7-[N-(4-trifluoromethylbenzoyl)-hydrazinocarbonyl]-tricyclo-[3.2.2.0...
Published 2024-12-01“…The disease was confirmed by PCR followed by determination of the nucleotide sequence of viral DNA by sequencing. Isolation of the new MPXV strain from clinical samples was carried out in Vero E6 cells. …”
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298
miR124a-3p inhibitor alleviates AFB1-induced hepatoxicity via targeting chicken glucocorticoid receptor mRNA
Published 2025-03-01“…Additionally, AFB1 induced oxidative stress and DNA damage. RT-qPCR showed reduced expression of certain Phase I/II metabolic detoxification enzymes and GR. …”
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299
Phylogeographic breaks and how to find them: An empirical attempt at separating vicariance from isolation by distance in a lizard with restricted dispersal
Published 2023-08-01“…Aim: Discontinuity in the distribution of genetic diversity (often based on mtDNA) is usually interpreted as evidence for phylogeographic breaks, underlying vicariant units. …”
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