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  1. 301

    Evolution by natural selection is a scientific law and not just a theory by Daniel J.M. Crouch, Walter F. Bodmer

    Published 2024-02-01
    “…The developing knowledge of prokaryotic microorganisms and the discovery of DNA or RNA as the fundamental basis of inheritance in all living organisms, together with Mendel’s laws, now provide the four basic conditions for evolution by natural selection, namely reproduction that is stable, but allows for variation that can increase fitness in the broadest sense. …”
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  2. 302

    Protocol for the purification and analysis of nuclear UFMylated proteins by Pudchalaluck Panichnantakul, Marlene Oeffinger

    Published 2025-03-01
    “…Summary: Protein UFMylation regulates numerous cellular processes including ribosome quality control and nuclear DNA repair. Here, we present a technique to isolate nuclei and purify UFMylated proteins under denaturing non-reducing conditions from commonly used mammalian cell line models such as hTERT-RPE1, HEK293, U2OS, and HCT116 cells. …”
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  3. 303

    Axon regeneration: an issue of translation by Schaeffer, Julia, Belin, Stephane

    Published 2024-12-01
    “…However, it is now well described that mRNA and protein levels correlate only partially in cells, and that the transcription process (from DNA to mRNA) may not directly reflect protein expression. …”
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  4. 304

    Mutual Effect of <i>NAT2</i> rs1799930 (590G>A) Polymorphism and Alcohol Abuse on Risk of Acute Pancreatitis by T. A. Samgina

    Published 2020-12-01
    “…Estimation of the contribution of rs1799930 (590G&gt;A) polymorphism of gene NAT2 to the development of acute alcoholic pancreatitis.Materials and methods. DNA samples were obtained from 547 unrelated patients with acute alcoholic pancreatitis and 573 unrelated individuals without gastrointestinal diseases. …”
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  5. 305

    Examining the epigenetic transmission of risk for chronic pain associated with paternal post-traumatic stress disorder: a focus on veteran populations by James Freeman, Sabrina Salberg, Melanie Noel, Richelle Mychasiuk

    Published 2025-02-01
    “…Numerous overlapping neurological pathways are implicated in both PTSD and chronic pain; many of which are susceptible to epigenetic modification, such as DNA methylation, histone modifications, and RNA regulation. …”
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  6. 306

    Mineral Plastics and Gels from Multi‐Arm Ionomers by Neta Shimony, Adi Gross, Boaz Mizrahi

    Published 2025-02-01
    “…This concept of synthesizing multi‐arm polymers with improved characteristics from building blocks of traditionally linear structures may be applicable to other mineral and bioplastic materials including acrylates, polysaccharides, and DNA.…”
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  7. 307

    Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome by Mimouni, Nour El Houda, Giacobini, Paolo

    Published 2024-04-01
    “…However, the underlying mechanisms of its transmission remain unknown, thus limiting the development of effective therapeutic strategies.This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.…”
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  8. 308

    Comprehensive transcriptome and proteome analysis revealed the molecular mechanisms of melatonin priming and waterlogging response in peach by Xianbin Gu, Linghong Lu, Jing Gao, Fei Fan, Genhua Song, Huiqin Zhang

    Published 2025-02-01
    “…Transcriptome analysis implicated genes related to ‘DNA-binding transcription factor activity’, such as AP2/ERF, HSF and WRKY transcription factors, in response to waterlogging. …”
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  9. 309

    Early life gut microbiome and its impact on childhood health and chronic conditions by Harold Nunez, Pamela A. Nieto, Ruben A. Mars, Maryam Ghavami, Cheryl Sew Hoy, Kimberley Sukhum

    Published 2025-12-01
    “…Some of these challenges are technical, such as lack of standardized stool collection protocols, inconsistent DNA extraction methods, and outdated sequencing technologies. …”
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  10. 310

    Nucleoside analogues in treatment of liver cirrhosis as an outcome of chronic hepatitis B by I. G. Bakulin

    Published 2009-02-01
    “…Terms of lamivudine treatment for patients with liver cirrhosis should be no less than 22 months, and clearance HBV DNA is achieved in 93,9 % of patients. Sustained virologic response (it was assessed in 4 years after termination of treatment course) is estimated as 39%. …”
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  11. 311

    The role of Airbnb creating a “new”-old city centre: facts, problems and controversies in Porto by Pedro Chamusca, José Rio Fernandes, Luís Carvalho, Thiago Mendes

    Published 2019-12-01
    “…We make use of qualitative and quantitative methods and draw on the official AirDNA database to analyse the relation between Airbnb and urban transformation, and the governance context. …”
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  12. 312

    Short tandem repeats delineate gene bodies across eukaryotes by William B. Reinar, Anders K. Krabberød, Vilde O. Lalun, Melinka A. Butenko, Kjetill S. Jakobsen

    Published 2024-12-01
    “…Recently, it has been shown that a broad range of transcription factors (TFs) are affected by STRs near or in the DNA target binding site. Despite this, the distribution of STR motif repetitiveness in eukaryote genomes is still largely unknown. …”
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  13. 313

    Commentary on &quot;Preliminary Species Hypotheses&quot; in Entomological Taxonomy: A Global Data and FAIR Infrastructure Perspective by Sharif Islam

    Published 2025-02-01
    “…In response to the need for rapid, scalable biodiversity monitoring, Buckley introduces preliminary species hypotheses (PSH) as a bridge between quick identification tools and the rigorous Linnaean system, leveraging DNA barcoding and AI-assisted image recognition to produce provisional classifications that can later be validated. …”
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  14. 314

    The biodiversity survey of the Cape (BioSCape), integrating remote sensing with biodiversity science by Anabelle W. Cardoso, Erin L. Hestir, Jasper A. Slingsby, Cherie J. Forbes, Glenn R. Moncrieff, Woody Turner, Andrew L. Skowno, Jacob Nesslage, Philip G. Brodrick, Keith D. Gaddis, Adam M. Wilson

    Published 2025-02-01
    “…In situ biodiversity observations of plant and animal communities, estuaries, kelp, and plankton were made using traditional field methods as well as novel approaches like environmental DNA and acoustic surveys. Biodiversity observations were accompanied by an unprecedented combination of airborne imaging spectroscopy and lidar measurements acquired across 45,000 km2. …”
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  15. 315

    Understanding cancer from an evolutionary perspective: high-risk reprogramming of genome-damaged stem cells by Vladimir F. Niculescu

    Published 2024-01-01
    “…Oxygen-sensitive germline and stem cells suffer DNA double-strand breaks due to stress and oxygen ranges reminiscent of ancestral hyperoxia, leading to cell senescence. …”
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  16. 316

    Integrating Legal Protection Strategies for Wife and Children Due to Rejection of Marriage Isbat Application by Abdul Jalil, Abdul Haq Syawqi, M. Haris Hidayatulloh, Umi Supraptiningsih, Cut Linda Marheni

    Published 2024-12-01
    “…Normatively, the way that can be taken is by integrating several aspects such as aspects of the law, law enforcement, and facilities or facilities that can support the application of law, such as human resources and sophisticated tools such as tools to find out a person's DNA. Meanwhile, sociologically, two aspects of social problems are crucial to carrying out an integrated improvement strategy, namely aspects such as aspects of a religious-type society and a negative patriarchal culture. …”
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  17. 317

    An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups by M. Sinan Beksaç, Emine Aydın, Mert Tuğral, Ergün Karaağaoğlu

    Published 2015-04-01
    “…STUDY DESIGN: This study is consisted of 3 groups of patients; 1) Pregnancies without MTHFR polymorphisms (n=65), 2) Pregnancies with methylenetetrahydrofolate reductase (MTHFR; homozygous or compound heterozygous) polymorphisms (n=140), 3) Pregnancies with “autoimmune antibody positivity” without any other type of hereditary thrombophilia (Anti-dsDNA, anti-phospholipid Ig G/M, anti-cardiolipin Ig G/M, ASMA, APA, ENA, anti-mitochondrial antibodies) (n=76). …”
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  18. 318

    A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

    Published 2025-01-01
    “…In this study, a novel crustin-like gene, Cqcarc1, was characterized from the redclaw crayfish Cherax quadricarinatus. The full-length cDNA sequence was 488 bp, and the open reading frame encoded 101 amino acids with a signal peptide in the N-terminus and a conserved WAP domain in the C-terminus. …”
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  19. 319

    Leveraging genomic insights from the neglected malaria parasites P. malariae and P. ovale using selective whole genome amplification (SWGA) approach by Fathia Ben-Rached, Amit Kumar Subudhi, Chang Li, Mariah Alawi, Rohit Satyam, Sui Xu, Guoding Zhu, Raeece Naeem, Sara Mfarrej, Di Liu, Zenaida Stead, Caroline Askonas, Yaobao Liu, Jun Cao, Arnab Pain

    Published 2025-02-01
    “…Furthermore, leveraging the long DNA fragments generated by SWGA, we achieved high-quality genome assemblies for P. malariae and P. ovale using PacBio long reads sequencing technology. …”
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  20. 320

    Detection of gene mutation in a case of Nagashima-type palmoplantar keratoderma by CAO Yuanyuan, YUAN Zhaojun, JIN Chuanyang, WANG Tianzi, LIAO Xiaojie, LIU Hong

    Published 2025-01-01
    “…[Methods] Clinical data of the patient were collected. Genomic DNA was extracted from the patient′s peripheral blood sample. …”
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