Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites by Thomas Kayser, MD, BS, Ronald Smulders, MD, PhD, Tomohiro Kusawake, PhD, Erik Wambre, PhD, Gurunadh R. Chichili, PhD, Mary B. Blauwet, DrPH, Anna Spence, MS, Melanie Patton, BS, Rima Tabash, PhD, Hannah A. DeBerg, PhD, Sugandhika Khosa, MS, Philipp Badorrek, MD, Jens M. Hohlfeld, MD, Brian C. Ferslew, PharmD, PhD

“…Conclusion: Intradermal DNA vaccine ASP2390 is safe and well tolerated but does not show an immunologic or clinical response in a small sample of adults allergic to HDM.…”
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DNA Empresarial: Uma Análise da Gênese à Operação das Micro e Pequenas Empresas de Santa Catarina by Jackson André da Silva, Nério Amboni, Anacleto Ângelo Ortigara, Alexandre Marino Costa

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Preimplantation aneuploidy screening using embryonic cell-free DNA isolated from spent culture medium: a case report by Lama Khudari, Marwan Halabi, Sahar Al Fahoum

Subjects: “…Embryonic cell-free DNA…”
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Comparison evaluation of bacterial DNA extraction methods for improved molecular diagnostic accuracy of sepsis-causing pathogens in clinical whole blood samples by Byungjoon Na, Junghun Park, Sojin Park, Eunseon Park, Jimin Jang, Yu-Hee Kim, Jinyeop Lee, Hae-Sun Chung

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Whether the Effect of Sperm DNA Fragmentation on the Clinical and Laboratory Outcomes Changes with the Paternal age in the intracytoplasmic sperm injection Cycles of Donor Oocytes by Deepthi Repalle, saritha kv, Shilpa Bhandari, Jitendra Choudhary

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Plasma mcfDNA Sequencing May Improve Usual Care Diagnostics to Detect HHV-8 Among Outpatient People with Advanced HIV by Sarah Park, Brian Epling, Morgan Richey, Daniel Lupu, Mona Mughar, Irini Sereti

“…The potential added benefit of the detection of other pathogens by mcfDNA sequencing may be particularly relevant for this population. …”
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RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining by Mansoor Hussain, Prabhat Khadka, Komal Pekhale, Tomasz Kulikowicz, Samuel Gray, Alfred May, Deborah L. Croteau, Vilhelm A. Bohr

“…Abstract RecQ helicases, highly conserved proteins with pivotal roles in DNA replication, DNA repair and homologous recombination, are crucial for maintaining genomic integrity. …”
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Preservation of cfRNA in cytological supernatants for cfDNA & cfRNA double detection in non‐small cell lung cancer patients by Yidan Ma, Yifei Wang, Lei He, Jun Du, Lin Li, Zhixin Bie, Yuanming Li, Xiaomao Xu, Wei Zhou, Xiaonan Wu, Li Yang, Jing Di, Chenyang Li, Xiaoguang Li, Dongge Liu, Zheng Wang

“…Abstract Backgroud Supernatants from various cytological samples, including body cavity effusion, sputum, bronchoalveolar lavage fluid (BALF), and needle aspiration, have been validated for detecting genetic alterations using cell‐free DNA (cfDNA) in patients with non‐small cell lung cancer (NSCLC). …”
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Environmental DNA-based assessment of multitrophic biodiversity in a typical river located in the Loess Plateau, China: Influence of PAHs and suspended sediments by Qian Li, Yulu Tian, Yongrong Hao, Chengkai Qu, Rungnapa Tagun, Hisato Iwata, Jiahua Guo

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The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLD by Wang Kedi, Xu Dongjiang, Gao Yan, Ma Kaihui, Zhao Wen

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Editorial: Current insights in Epigenetics and Epigenomics by Steven Henikoff, Steven Henikoff, Sharon Y. R. Dent, Sharon Y. R. Dent, Raul Mostoslavsky, Raul Mostoslavsky, Ting Wang, Luca Comai

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Visualisation of nucleotide sequences by Tomas Rekašius

Subjects: “…DNA sequences…”
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EVALUACIÓN NEUROPSICOLÓGICA EN POBLACIÓN ADULTA; INSTRUMENTOS DE EVALUACIÓN by Esperanza Bausela Herreras

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Abnormal methylation of Mill1 gene regulates osteogenic differentiation involved in various phenotypes of skeletal fluorosis in rats and methionine intervention by Niannian Chen, Jing Zhang, Congyu Yin, Yudan Liao, Lei Song, Ting Hu, Xueli Pan

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Real-time analysis of initiation regulation systems during the progression of the reconstituted chromosomal replication cycle by Koki Kanoh, Masayuki Su’etsugu

Subjects: “…DNA amplification…”
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Diet-microbiome covariation across three giraffe species in a close-contact zone by Elin Videvall, Brian A. Gill, Michael B. Brown, Hannah K. Hoff, Bethan L. Littleford-Colquhoun, Peter Lokeny, Paul M. Musili, Tyler R. Kartzinel

Subjects: “…DNA metabarcoding…”
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The evolutionarily diverged single-stranded DNA-binding proteins SSB1/SSB2 differentially affect the replication, recombination and mutation of organellar genomes in Arabidopsis thaliana by Weidong Zhu, Jie Qian, Yingke Hou, Luke R. Tembrock, Liyun Nie, Yi-Feng Hsu, Yong Xiang, Yi Zou, Zhiqiang Wu

“…Single-stranded DNA-binding proteins (SSBs) play essential roles in the replication, recombination and repair processes of organellar DNA molecules. …”
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Embryonic heat conditioning induces paternal heredity of immunological cross- tolerance: coordinative role of CpG DNA methylation and miR-200a regulation by Padma Malini Ravi, Tatiana Kisliouk, Shelly Druyan, Amit Haron, Mark A. Cline, Elizabeth R. Gilbert, Noam Meiri

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Culture-independent detection of Mycobacterium tuberculosis complex DNA using targeted next generation sequencing in African buffalo (Syncerus caffer) oronasal swabs in South Africa by Sinegugu Kholeka Mhlophe, Charlene Clarke, Giovanni Ghielmetti, Giovanni Ghielmetti, Megan Matthews, Tanya Jane Kerr, Michele Ann Miller, Wynand Johan Goosen, Wynand Johan Goosen

“…Mycobacterium tuberculosis complex DNA, along with various NTM species, were identified in 8/19 samples. …”
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Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription by Lipeng Pei, Yan Zhu, Wenpeng Li, Bin Xu, Jingli Sun

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