Showing 161 - 180 results of 504 for search '"DNA"', query time: 0.04s Refine Results
  1. 161
  2. 162

    Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment. by Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C deCarvalho

    Published 2025-01-01
    “…Glioblastoma (GBM) tumors exhibit extensive genomic, epigenomic, and transcriptional diversity, with significant intratumoral heterogeneity, complicating standard treatment approaches involving radiation (RT) and the DNA-alkylating agent temozolomide (TMZ). In this study, we employed an integrative multi-omics approach, including targeted proteomics, transcriptomics, genomics, and DNA methylation profiling, to investigate the response of a representative panel of GBM patient-derived cancer stem cells (CSCs) to astrocytic differentiation and RT and TMZ treatments. …”
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  3. 163

    Molecular Identification of Fusarium proliferatum from toenails: A case report by Sazan Jamal Gharib, Nawroz Abdul-razzak Tahir

    Published 2019-08-01
    “…Infectious fungal molecular detection advances the select of right antifungal therapy, in that way improving the medication rate of nails infections. DNA sequence analysis and Phylogenetic tree of the amplified ITS-rDNA was used for species identification of this strain of F. proliferatum. …”
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  4. 164

    Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair by Shishi Tao, Yue Pu, Eun Ju Yang, Guowen Ren, Changxiang Shi, Li-Jie Chen, Liang Chen, Joong Sup Shim

    Published 2025-01-01
    “…Conversely, FHIT-deficient cells are highly dependent on HRR for survival under DNA damage stress. The inhibition of GSK3β in FHIT-deficient cells suppressed the ATR/BRCA1/RAD51 axis in HRR signaling via two distinct pathways and suppressed DNA double-strand break repair, leading to the accumulation of DNA damage and apoptosis. …”
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  5. 165

    Diagnostic efficacy of serological and epigenetic methods of screening diagnostics of colorectal cancer by O. I. Kit, D. V. Burtsev, A. Yu. Maksimov

    Published 2014-12-01
    “…Epigenetic tests for DNA methylate of SEPT9 gene in blood as screening procedure was characterized by high diagnostic efficacy — 86,5%. …”
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  6. 166

    Fitting Markov property to genetic sequences by Jurgita Židanavičiūtė, Tomas Rekašius

    Published 2023-09-01
    “… In this paper DNA sequents are modelled as discrete-state Markov chains. …”
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  7. 167

    Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

    Published 2025-02-01
    “…MAGEA4 interacts with proteins including Miz-1, p53, and RAD18, participating in gene transcription regulation and DNA damage repair. By stabilizing RAD18, MAGEA4 facilitates the recruitment of Y-family DNA polymerases, enabling cells to continue replication under DNA damage conditions and thus supporting cancer cell survival. …”
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  8. 168

    Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response by Sophie C. van der Horst, Leonie Kollenstart, Amandine Batté, Sander Keizer, Kees Vreeken, Praveen Pandey, Andrei Chabes, Haico van Attikum

    Published 2025-02-01
    “…Abstract Perturbation of DNA replication, for instance by hydroxyurea-dependent dNTP exhaustion, often leads to stalling or collapse of replication forks. …”
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  9. 169

    Healthy Eating: Folate by Linda B. Bobroff

    Published 2011-04-01
    “…It is involved in the formation of DNA and amino acids. DNA is the genetic material found in all cells of your body. …”
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  10. 170

    What is Agricultural Biotechnology? by Maria Gallo-Meagher, Stephen G. Fulford

    Published 2003-06-01
    “… Biotechnology, specifically genetic engineering, is the manipulation of an organism's DNA in order to direct that organism to perform a specific and useful task. …”
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  11. 171
  12. 172

    Hormone Receptors in Cervicovaginal Cells by Şayeste Demirezen, Funda Gerçeker, Sinan Beksaç

    Published 2013-04-01
    “…Afterwards, hormone-bound receptor dimerizes with another receptor and then the dimer binds to specific DNA sequence through the DBD. Consequently, hormones regulate gene transcription via a direct interaction with DNA. …”
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  13. 173

    Biochemistry / by Pelley, John W.

    Published 2011
    Table of Contents: “…Carbohydrates, lipids, and amino acids : metabolic fuels and biosynthetic precursors -- Proteins and enzymes -- Membrane biochemistry and signal transduction -- Nutrition -- Generation of energy from dietary fuels -- Carbohydrate metabolism -- Lipid metabolism -- Nitrogen metabolism -- Integration of metabolism -- Nucleotide synthesis and metabolism -- Organization, synthesis, and repair of DNA -- Gene expression -- DNA technology -- Common laboratory values.…”
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  14. 174

    Healthy Eating: Folate by Linda B. Bobroff

    Published 2011-04-01
    “…It is involved in the formation of DNA and amino acids. DNA is the genetic material found in all cells of your body. …”
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    Article
  15. 175

    What is Agricultural Biotechnology? by Maria Gallo-Meagher, Stephen G. Fulford

    Published 2003-06-01
    “… Biotechnology, specifically genetic engineering, is the manipulation of an organism's DNA in order to direct that organism to perform a specific and useful task. …”
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    Article
  16. 176

    Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing. by Tiana M Scott, Lydia M Arnold, Jordan A Powers, Delaney A McCann, Ana B Rowe, Devin E Christensen, Miguel J Pereira, Wen Zhou, Rachel M Torrez, Janet H Iwasa, Philip J Kranzusch, Wesley I Sundquist, Jarrod S Johnson

    Published 2025-01-01
    “…Retroviruses can be detected by the innate immune sensor cyclic GMP-AMP synthase (cGAS), which recognizes reverse-transcribed DNA and activates an antiviral response. However, the extent to which HIV-1 shields its genome from cGAS recognition remains unclear. …”
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  17. 177

    Genetics : analysis of genes and genomes / by Hartl, Daniel L., Cochrane, Bruce

    Published 2019
    Table of Contents: “…Genes, genomes and genetic analysis -- DNA structure and genetic variation -- Transmission genetics : the principle of segregation -- The chromosomal basis of inheritance -- Genetic linkage and chromosome mapping -- Human karyotypes and chromosome behavior -- The genetics of complex characters -- Genetics of the bacteria and their viruses -- Molecular organization of chromosomes and genomes -- DNA replication and sequencing -- Mutation, repair, and recombination -- Molecular biology of gene expression -- Molecular mechanisms of gene regulation -- Manipulating genes and genomes -- Genetic control of development -- The genetics of cancer -- Extranuclear inheritance -- Genetics of populations -- Human evolution.…”
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  18. 178

    Principles of Medical Biochemistry / by Meisenberg, Gerhard

    Published 2017
    Table of Contents: “…Introduction to biomolecules -- Introduction to protein structure -- Oxygen-binding proteins : hemoglobin and myoglobin -- Enzymatic reactions -- Coenzymes -- DNA, RNA, and protein synthesis -- The human genome -- Protein targeting and proteostasis -- Introduction to genetic diseases -- Viruses -- DNA technology -- Biological membranes -- The cytoskeleton -- The extracellular matrix -- Extracellular messengers -- Intracellular messengers -- Plasma proteins -- Defense mechanisms -- Cellular growth control and cancer -- Digestive enzymes -- Introduction to metabolic pathways -- Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation -- Oxygen deficiency and oxygen toxicity -- Carbohydrate metabolism -- The metabolism of fatty acids and triglycerides -- The metabolism of membrane lipids -- Lipid transport -- Amino acid metabolism -- Metabolism of iron and heme -- The metabolism of purines and pyrimidines -- Micronutrients -- Integration of metabolism.…”
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  19. 179

    Molecular-assisted analysis of indigenous chicken semen to increase rooster fertility in tropics by Jacob Alhassan Hamidu, Richard Tsekumah, Amina Iddrisu, Stepehn Gariba, Mitchell Agyei Opoku, Emmanuel Kafari, Kofi Appenteng, Patrick Nana Kyere

    Published 2023-05-01
    “…However, the sperm motility pattern indicated that the movement of sperm in NN males was better than NF birds. DNA fragments from NF chicken sperms were lighter in weight and ran faster through the gel matrix, indicating higher amount of DNA fragmentation than the NN chickens. …”
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  20. 180

    A novel isothermal whole genome sequencing approach for Monkeypox Virus by Matthias Licheri, Manon Flore Licheri, Lukas Probst, Cora Sägesser, Pascal Bittel, Franziska Suter-Riniker, Ronald Dijkman

    Published 2024-09-01
    “…The latter allows multiplexing due to the efficient enrichment of the viral DNA, however, mutations or the presence of different clades can negatively influence genome coverage yield. …”
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