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161
De-biasing microbiome sequencing data: bacterial morphology-based correction of extraction bias and correlates of chimera formation
Published 2025-02-01“…Extracted DNA was sequenced (V1–V3 16S rRNA gene) together with corresponding DNA mocks. …”
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162
Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment.
Published 2025-01-01“…Glioblastoma (GBM) tumors exhibit extensive genomic, epigenomic, and transcriptional diversity, with significant intratumoral heterogeneity, complicating standard treatment approaches involving radiation (RT) and the DNA-alkylating agent temozolomide (TMZ). In this study, we employed an integrative multi-omics approach, including targeted proteomics, transcriptomics, genomics, and DNA methylation profiling, to investigate the response of a representative panel of GBM patient-derived cancer stem cells (CSCs) to astrocytic differentiation and RT and TMZ treatments. …”
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163
Molecular Identification of Fusarium proliferatum from toenails: A case report
Published 2019-08-01“…Infectious fungal molecular detection advances the select of right antifungal therapy, in that way improving the medication rate of nails infections. DNA sequence analysis and Phylogenetic tree of the amplified ITS-rDNA was used for species identification of this strain of F. proliferatum. …”
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164
Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair
Published 2025-01-01“…Conversely, FHIT-deficient cells are highly dependent on HRR for survival under DNA damage stress. The inhibition of GSK3β in FHIT-deficient cells suppressed the ATR/BRCA1/RAD51 axis in HRR signaling via two distinct pathways and suppressed DNA double-strand break repair, leading to the accumulation of DNA damage and apoptosis. …”
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165
Diagnostic efficacy of serological and epigenetic methods of screening diagnostics of colorectal cancer
Published 2014-12-01“…Epigenetic tests for DNA methylate of SEPT9 gene in blood as screening procedure was characterized by high diagnostic efficacy — 86,5%. …”
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166
Fitting Markov property to genetic sequences
Published 2023-09-01“… In this paper DNA sequents are modelled as discrete-state Markov chains. …”
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167
Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy
Published 2025-02-01“…MAGEA4 interacts with proteins including Miz-1, p53, and RAD18, participating in gene transcription regulation and DNA damage repair. By stabilizing RAD18, MAGEA4 facilitates the recruitment of Y-family DNA polymerases, enabling cells to continue replication under DNA damage conditions and thus supporting cancer cell survival. …”
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168
Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response
Published 2025-02-01“…Abstract Perturbation of DNA replication, for instance by hydroxyurea-dependent dNTP exhaustion, often leads to stalling or collapse of replication forks. …”
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169
Healthy Eating: Folate
Published 2011-04-01“…It is involved in the formation of DNA and amino acids. DNA is the genetic material found in all cells of your body. …”
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170
What is Agricultural Biotechnology?
Published 2003-06-01“… Biotechnology, specifically genetic engineering, is the manipulation of an organism's DNA in order to direct that organism to perform a specific and useful task. …”
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171
An Effective and Safe Maize Seed Chipping Protocol Using Clipping Pliers With Applications in Small-Scale Genotyping and Marker-Assisted Breeding
Published 2025-02-01“…For three of the methods, seed-based DNA was of comparable quality to DNA extracted from leaf punches. …”
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172
Hormone Receptors in Cervicovaginal Cells
Published 2013-04-01“…Afterwards, hormone-bound receptor dimerizes with another receptor and then the dimer binds to specific DNA sequence through the DBD. Consequently, hormones regulate gene transcription via a direct interaction with DNA. …”
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173
Biochemistry /
Published 2011Table of Contents: “…Carbohydrates, lipids, and amino acids : metabolic fuels and biosynthetic precursors -- Proteins and enzymes -- Membrane biochemistry and signal transduction -- Nutrition -- Generation of energy from dietary fuels -- Carbohydrate metabolism -- Lipid metabolism -- Nitrogen metabolism -- Integration of metabolism -- Nucleotide synthesis and metabolism -- Organization, synthesis, and repair of DNA -- Gene expression -- DNA technology -- Common laboratory values.…”
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174
Healthy Eating: Folate
Published 2011-04-01“…It is involved in the formation of DNA and amino acids. DNA is the genetic material found in all cells of your body. …”
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175
What is Agricultural Biotechnology?
Published 2003-06-01“… Biotechnology, specifically genetic engineering, is the manipulation of an organism's DNA in order to direct that organism to perform a specific and useful task. …”
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176
Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing.
Published 2025-01-01“…Retroviruses can be detected by the innate immune sensor cyclic GMP-AMP synthase (cGAS), which recognizes reverse-transcribed DNA and activates an antiviral response. However, the extent to which HIV-1 shields its genome from cGAS recognition remains unclear. …”
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177
Genetics : analysis of genes and genomes /
Published 2019Table of Contents: “…Genes, genomes and genetic analysis -- DNA structure and genetic variation -- Transmission genetics : the principle of segregation -- The chromosomal basis of inheritance -- Genetic linkage and chromosome mapping -- Human karyotypes and chromosome behavior -- The genetics of complex characters -- Genetics of the bacteria and their viruses -- Molecular organization of chromosomes and genomes -- DNA replication and sequencing -- Mutation, repair, and recombination -- Molecular biology of gene expression -- Molecular mechanisms of gene regulation -- Manipulating genes and genomes -- Genetic control of development -- The genetics of cancer -- Extranuclear inheritance -- Genetics of populations -- Human evolution.…”
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178
Principles of Medical Biochemistry /
Published 2017Table of Contents: “…Introduction to biomolecules -- Introduction to protein structure -- Oxygen-binding proteins : hemoglobin and myoglobin -- Enzymatic reactions -- Coenzymes -- DNA, RNA, and protein synthesis -- The human genome -- Protein targeting and proteostasis -- Introduction to genetic diseases -- Viruses -- DNA technology -- Biological membranes -- The cytoskeleton -- The extracellular matrix -- Extracellular messengers -- Intracellular messengers -- Plasma proteins -- Defense mechanisms -- Cellular growth control and cancer -- Digestive enzymes -- Introduction to metabolic pathways -- Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation -- Oxygen deficiency and oxygen toxicity -- Carbohydrate metabolism -- The metabolism of fatty acids and triglycerides -- The metabolism of membrane lipids -- Lipid transport -- Amino acid metabolism -- Metabolism of iron and heme -- The metabolism of purines and pyrimidines -- Micronutrients -- Integration of metabolism.…”
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179
Molecular-assisted analysis of indigenous chicken semen to increase rooster fertility in tropics
Published 2023-05-01“…However, the sperm motility pattern indicated that the movement of sperm in NN males was better than NF birds. DNA fragments from NF chicken sperms were lighter in weight and ran faster through the gel matrix, indicating higher amount of DNA fragmentation than the NN chickens. …”
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180
A novel isothermal whole genome sequencing approach for Monkeypox Virus
Published 2024-09-01“…The latter allows multiplexing due to the efficient enrichment of the viral DNA, however, mutations or the presence of different clades can negatively influence genome coverage yield. …”
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