Using the Oxford Foot Model to determine the association between objective measures of foot function and results of the AOFAS Ankle-Hindfoot Scale and the Foot Function Index: a pr... by Frank Krummenauer, Tanja Kostuj, Felix Stief, Kirsten Anna Hartmann, Katharina Schaper, Mohammad Arabmotlagh, Mike H Baums, Andrea Meurer, Sebastian Lieske

“…Objective After cross-cultural adaption for the German translation of the Ankle-Hindfoot Scale of the American Orthopaedic Foot and Ankle Society (AOFAS-AHS) and agreement analysis with the Foot Function Index (FFI-D), the following gait analysis study using the Oxford Foot Model (OFM) was carried out to show which of the two scores better correlates with objective gait dysfunction.Design and participants Results of the AOFAS-AHS and FFI-D, as well as data from three-dimensional gait analysis were collected from 20 patients with mild to severe ankle and hindfoot pathologies.Kinematic and kinetic gait data were correlated with the results of the total AOFAS scale and FFI-D as well as the results of those items representing hindfoot function in the AOFAS-AHS assessment. …”
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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? by Marka Crittenden, Sandra Demaria, C Norman Coleman, Jonathan Schoenfeld, Arta Monjazeb, Samir Khleif, Seema Gupta, Andrew Sikora, Zachary Morris, Chandan Guha, Stephen Shiao, Silvia Chiara Formenti, Bhadrasain Vikram, Mansoor M Ahmed

“…Similarly, preclinical studies should be designed as much as possible to model the intended clinical setting. …”
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Optimasi Proses Klasterisasi di MySQL DBMS dengan Mengintegrasikan Algoritme MIC-Kmeans Menggunakan Bahasa SQL dalam Stored Procedure by Issa Arwani

“…The integration process includes 4 stages, there are dataset initialization, SQL algorithm mapping and dataset table, SQL design for each mapping result, and implementation SQL in the MySQL stored procedure. …”
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RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

“…The SARS-CoV-2 receptor-binding domain (RBD) is a key antigen in vaccine design. However, its low immunogenicity has been a hurdle, resulting in the production of minimal anti-RBD antibodies even when combined with alum adjuvant. …”
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Perancangan dan Implementasi Sistem Informasi Deteksi Kesesuaian Pemanfaatan Ruang Berbasis Web dengan Fitur Geo-Intersection Pada POSTGIS by Issa Arwani, Widhy Hayuhardhika Nugraha Putra, Ghazian Hamdi, Tsania Dzulkarnain

“…Therefore, development research was carried out in this study to design and implement web-GIS based space utilization suitability detection based on RSP of North Kalimantan Province. …”
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Sistemas de creencias parentales y orientación cultural en niños y niñas en cuidado transitorio: estudio de caso en una aldea gubernamental en Costa Rica/ Parental Belief Systems a... by Esteban Durán-Delgado, Mariano Rosabal-Coto

“…We discuss how the context and the culture have a homogenizing function with regards to trajectories for development. Based on a mixed-design context-sensitive methodological approach, we worked in a publicly-run institution for transitory care. …”
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Comparison of different GnRH compounds on fertility outcomes in ovulation synchronized and presynchronized beef cows by Nicola Oosthuizen, Lucas M. Goncalves, Samir Burato, Molly S. Smith, Kelsey M. Harvey, Graham Cliff Lamb, Graham Cliff Lamb, Pedro L. P. Fontes

“…Cows (n = 1,585) were enrolled in a completely randomized design with a 2×2 factorial arrangement of treatments. …”
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Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study by Xiyu Wei, Chao Li, Dongyu Liu, Jieyi Chen, Yumeng Ju, Jin Liu, Bangshan Liu, Yan Zhang

“…Methods The present study utilized a three-year longitudinal cohort design, with data from the China Health and Retirement Longitudinal Study (CHARLS). 4,869 participants aged 60–97 years from CHARLS wave 2015 and 2018 who were cognitively and physically healthy were included in analysis. …”
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Advancements in 3D printing technologies for personalized treatment of osteonecrosis of the femoral head by Tingting Chen, Lincong Luo, Jiaying Li, Jiamin Li, Tao Lin, Mingrui Liu, Hang Sang, Xinyu Hong, Jiahao Pu, Wenhua Huang

“…By introducing gradient porous scaffolds, bioactive material coatings, and AI-assisted design, this work outlines novel strategies to improve bone regeneration and personalized hip-preserving interventions. …”
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Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph... by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

“…Our previous pilot study indicated that a reduced starting dose of lenvatinib may maintain comparable anti-tumor activity with favorable safety in heavily pre-treated ovarian cancer. This study is designed to further validate the efficacy and safety of the combination therapy of low-dose lenvatinib and PD-1 inhibitor toripalimab in patients with recurrent PROC.Study Design and Methods: The study is designed as a multicenter, open-label, single-arm, prospective phase II study. …”
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Fluid balance and clinical outcomes in patients with aortic dissection: a retrospective case-control study based on ICU databases by Tao Chen, Peng Qiu, Yixuan Li, Xinwu Lu, Zhaoyu Wu, Zhijue Xu, Hongji Pu, Jiahao Lei, Zhuojing Zhang, Xinrui Yang, Ruihua Wang

“…This paper explores the role of fluid management in the clinical care of AD patients, which has been unclear despite the substantial existing research that has been conducted on the treatment of AD.Design A retrospective case-control study using data for AD patients from public databases.Setting Two public intensive care unit (ICU) databases with hospital courses from the USA, Medical Information Mart for Intensive Care (MIMIC)-IV critical care dataset and the eICU Collaborative Research Database, with data from 2008 to 2019.Participants A total of 751 adult AD patients with detailed fluid management records from two databases were included.Interventions The mean 24-hour intake and output were calculated by dividing the total amount of intake and output by the number of days in the ICU, respectively. …”
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Sistem Alarm Penggantian Cairan Infus Berbasis Mikrokontroler menggunakan Wireless by Leila Nurfitria, Susanto Sambasri, Salita Ulitia Prini

“…Abstract Some hospitals that have a larger number of patients than nurse duty so as to cause negligence in controlling causing problems in the organs system due to fluid replacement is done late or even infusion fluid does not drip due to faulty tool, so we created notification system for control hospital infusion fluid using a microcontroller and wireless connected to the nurses room. The design of this infusion alarm system using photodioda and infrared as a detector of the presence of infusion fluids that drip, as well as to calculate the volume of intravenous fluids. …”
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Types of electronic nicotine delivery systems (ENDS) used by people of different age and smoking status groups: results from a US nationally representative survey by Lucy Popova, Robert T Fairman, David L Ashley, Zachary B Massey, Bai Cham, Ruiyan Luo, Mohammed Alqahtani, Scott Weaver

“…This study sought to identify differences in the use of ENDS device type based on age and cigarette use status to inform policy about regulating ENDS.Design This was a cross-sectional study.Setting Data was derived from a national survey conducted in 2021 in the USA.Participants Participants include 2369 US youth and adults (13 years or older) who reported past 30-day ENDS use.Outcome measures Past 30-day fairly regular use (i.e., several times a week or more) of ENDS device types, namely cigalikes, disposables, refillable tank/box mods, closed pods, refillable pods and drippers. …”
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The Effects of Presenting AI Uncertainty Information on Pharmacists’ Trust in Automated Pill Recognition Technology: Exploratory Mixed Subjects Study by Jin Yong Kim, Vincent D Marshall, Brigid Rowell, Qiyuan Chen, Yifan Zheng, John D Lee, Raed Al Kontar, Corey Lester, Xi Jessie Yang

“…ObjectiveThis study aims to investigate pharmacists’ trust in automated pill verification technology designed to support medication dispensing. …”
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Effects of Bride Price on Women's Rights Among the Bakiga in Kabale District: A Case Study of Kitumba Sub-County. by Asiimwe, Bettus

“…The study used an exploratory and descriptive study design. Both qualitative and quantitative research methods were used in the study. …”
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Risk factors for thromboembolic and bleeding events in anticoagulated patients with atrial fibrillation: the prospective, multicentre observational PREvention oF thromboembolic eve... by Raffaele De Caterina, Kurt Huber, Richard Schilling, Miklos Rohla, Thomas W Weiss, Ladislav Pecen, Giuseppe Patti, Jolanta M Siller-Matula, Renate B Schnabel, Dipak Kotecha, Markus Lucerna, Paulus Kirchhof

“…Objectives We identified factors associated with thromboembolic and bleeding events in two contemporary cohorts of anticoagulated patients with atrial fibrillation (AF), treated with either vitamin K antagonists (VKA) or non-VKA oral anticoagulants (NOACs).Design Prospective, multicentre observational study.Setting 461 centres in seven European countries.Participants 5310 patients receiving a VKA (PREvention oF thromboembolic events - European Registry in Atrial Fibrillation (PREFER in AF), derivation cohort) and 3156 patients receiving a NOAC (PREFER in AF Prolongation, validation cohort) for stroke prevention in AF.Outcome measures Risk factors for thromboembolic events (ischaemic stroke, systemic embolism) and major bleeding (gastrointestinal bleeding, intracerebral haemorrhage and other life-threatening bleeding).Results The mean age of patients enrolled in the PREFER in AF registry was 72±10 years, 40% were female and the mean CHA2DS2-VASc Score was 3.5±1.7. …”
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Intravenous nicardipine and labetalol use in hypertensive patients with signs or symptoms suggestive of end-organ damage in the emergency department: a subgroup analysis of the CLU... by Brian Hiestand, Phillip Levy, W Frank Peacock, Brigitte M Baumann, Richard M Nowak, Amy Hsu, Joseph Varon, Chad M Cannon, David M Cline, Pierre Borczuk, Abhinav Chandra, Deborah B Diercks, Preeti Jois, Brian Kaminski, Jon W Schrock

“…Objective To compare the efficacy of Food and Drug Administration recommended dosing of nicardipine versus labetalol for the management of hypertensive patients with signs and/or symptoms (S/S) suggestive of end-organ damage (EOD).Design Secondary analysis of the multicentre prospective, randomised CLUE trial.Setting 13 academic emergency departments in the USA.Participants Eligible patients had two systolic blood pressure (SBP) measures ≥180 mm Hg at least 10 min apart, no contraindications to nicardipine or labetalol and predefined S/S suggestive of EOD on arrival.Interventions Medications were administered by continuous infusion (nicardipine) or repeat intravenous bolus (labetalol) for a study period of 30 min or until a specified target SBP ±20 mm Hg was achieved.Primary outcome measure Percentage of participants achieving a predefined target SBP range (TR) defined as an SBP within ±20 mm Hg as established by the treating physician.Results Of the 141 eligible patients, 49.6% received nicardipine, 51.7% were women and 81.6% were black. …”
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KMS (Knowledge Management System) Obat Ibu Hamil Berbasis Android by Halimah Tus Sadiah, Muhamad Saad Nurul Ishlah, Nyayu Siti Aminah Lily Elfrieda, Mauladani Adi Gasbara

“…This research uses the Knowledge Management System Life Cycle (KMSLC) method which consists of several stages, namely evaluation of infrastructure, team building, knowledge capture, design of the KMS blueprint, verification and validation, implementation of KMS, and KMS testing. …”
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Should Echocardiographic Evaluation Be Performed Routinely in the First 72 Hours in Extremely Low Birth Weight Babies? by Ruya Colak, Senem Alkan Ozdemir, Ezgi Yangin Ergon, Ferit Kulali, Oguz Han Kalkanli, Tulin Gokmen Yildirim, Murat Muhtar Yilmazer, Cuneyt Zihni, Sebnem Calkavur

“…In our study, we aimed to evaluate the necessity of performing routine echocardiography(ECHO) in the first 72hours in ELBW infants. Study Design:This study was planned retrospectively and observationally.Between June2016 and December2018,36 patients diagnosed with hemodynamically significant PDA(hsPDA) who were hospitalized in the neonatal intensive care unit(NICU),with ≤28Gw or ≤1000g were included in this study.These babies were routinely performed ECHO for PDA between 24-72hours,although they were asymptomatic in the period from June2016 to December2017(n:23).Between January2018 and December2018, patients without PDA symptoms were expected to complete 72hours for routine PDA screening (n:13).The patients were divided into 2 groups as early ECHO group(EEG)(n=23) and late ECHO group (LEG)(n=13).In the presence of at least one of the clinical signs of systemic hypoperfusion and/or pulmonary hyperperfusion, symptomatic PDA was accepted and closure treatment was  applied with ibuprofen(n: 23) or paracetamol(n: 5).While the two groups were compared in terms of demographic features,ECHO findings,and the state of taking closure therapy,patients receiving closure therapy were compared in terms of mortality and premature morbidity. …”
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Computational analysis of heat transfer and fluid flow characteristics in a diamond microchannel heat sink with orthogonal ribs by Liang Du, Wenbo Hu, Ningkang Deng, Zhaoyang Zhang, Hongxing Wang

“…Therefore, the unique rib arrangement design of the orthogonal rib microchannel heat sink not only optimizes fluid flow and enhances heat transfer capacity but also effectively addresses the heat dissipation challenges of electronic devices. …”
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