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6401
A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor
Published 2025-02-01“…To address this issue, we designed and synthesised a novel lipidated phosphomimetic peptide inhibitor targeting β-arrestins, called ARIP, which was developed based on the C-terminal tail (A343-S371) of the vasopressin V2 receptor. …”
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6402
A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins
Published 2025-02-01“…Inducing viral capsid protein (CP) degradation via hydroxyl radicals (∙OH) generated by an in situ Fenton-like reaction within plant pathogenic tissues is proposed for combating plant viruses in this study. We designed a new Fenton-like reaction inducer, tCuinter-bCDs, which utilizes an internal doping strategy that reduces copper content by 89.89% compared to conventional doping methods, while still achieving a high coexistence of multivalent copper ions. …”
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6403
Soap and water cleaning versus bleach-based cleaners for eliminating SARS-CoV-2 infection
Published 2025-01-01“…We prioritised systematic reviews and randomised studies and only included other study designs, such as laboratory studies, which had interventions of relevant interest. …”
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6404
Optimizing the dose-averaged linear energy transfer for the dominant intraprostatic lesions in high-risk localized prostate cancer patients
Published 2025-01-01“…Two treatment plans were designed for each patient: 1) conventional plan optimized by the single-field uniform dose technique, and 2) boost plan optimized by the multifield optimization and LET painting technique, to achieve LETd boost within the PTVboost. …”
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6405
The Impact of Cementing Techniques on Implant Longevity in Relation to Keel Length in Persona and NexGen Knee Arthroplasty: A Comprehensive Study
Published 2025-02-01“…Conclusions: In conclusion, meticulous cementing techniques can reduce the rate of tibial loosening in shorter keel designs.…”
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6406
High Stability Single-Port Dual Band Microwave Sensor Based on Interdigital Capacitor Structure With Asymmetry Branch Feedline
Published 2025-01-01“…The microwave sensor is designed using a single-port resonator operating at two different resonant frequencies <inline-formula> <tex-math notation="LaTeX">$f_{r1} = 1.61$ </tex-math></inline-formula> GHz and <inline-formula> <tex-math notation="LaTeX">$f_{r2} = 2.52$ </tex-math></inline-formula> GHz. …”
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6407
Image-based anomaly detection in low-light industrial environments with feature enhancement
Published 2025-03-01“…In this paper, we present DarkAD, a novel end-to-end approach specifically designed to address the difficulties of anomaly detection under low-light conditions. …”
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6408
Impact of empiric antibiotics on risk of Clostridioides difficile—a causal inference observational analysis
Published 2025-01-01“…Causal inference observational study designs can be used to estimate patient-level harms of interventions such as empiric antimicrobials. …”
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6409
Odor symptom management in patients with malignant wounds in Mali: the use of a cinnamon dressing
Published 2025-02-01“…Cinesteam® Cinnamon Dressing is an adsorbent dressing designed to reduce odors. This study aimed at demonstrating the feasibility of routine use of cinnamon dressing in the Malian context, and to assess its effect on tumor wound odors. …”
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6410
Early health technology assessment of tongue swab for non-sputum based pulmonary tuberculosis diagnosis in ThailandResearch in context
Published 2025-02-01“…The TPP outlines three target levels to guide innovators in designing effective clinical studies. Findings: The landscape review identified the clinical workflow and reimbursement process of all PTB diagnostic tests in Thailand. …”
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6411
The prevalence of online food delivery service usage and its association with anthropometric measurements in Muscat, Oman; a cross-sectional study
Published 2025-02-01“…Future research should include other regions of Oman and adopt prospective longitudinal designs.…”
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6412
The clinical value of computed tomography Hounsfield unit for diagnosing palpable inguinal lymph node metastasis in patients with penile cancer
Published 2025-02-01“…BackgroundComputed tomography (CT) Hounsfield units (HUs) of pathologically confirmed metastatic inguinal lymph nodes (ILNs) were proved to be higher than negative ones. We designed this study to explore the clinical value of CT HU for diagnosing palpable ILN metastasis in patients with penile cancer.MethodsA total of 32 patients with penile cancer, including 84 palpable ILNs, were recruited in this study. …”
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6413
A systematic review of military-to-civilian transition, The role of gender.
Published 2025-01-01“…Female veterans also struggled with the legacies of gender inequality, discrimination, and sexual assault which affected their development of a female veteran identity and affected the provision of services designed to meet their needs as a female. Despite these challenges, female veterans' expressed pride in their service and accomplishments.…”
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6414
Detection of Masses in Mammogram Images Based on the Enhanced RetinaNet Network With INbreast Dataset
Published 2025-02-01“…This strategic adjustment was designed to prevent the loss of resolution for small mass features. …”
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6415
Differences in Physical and Psychological Parameters in Sub-Elite, Male, Youth Soccer Players with Jumper's Knee Following Physical Therapy Compared to Healthy Controls: A Longitud...
Published 2021-02-01“… # Conclusions The observed findings imply that there are significant differences in physical and psychological performance of youth soccer players after physical therapy for JK compared to HC. When designing rehabilitation and/or training programs, as well as determining the point of return to sport the impact of the injury needs to be taken into account…”
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6416
The effectiveness of dyadic interventions for health outcomes of prostate cancer patients and informal caregivers: a systematic review and meta-analysis
Published 2025-02-01“…However, given features such as research quality and sample size, further randomized controlled trials with excellent study designs are needed in the future to evaluate and validate the efficacy of dyadic care treatments for patients with prostate cancer. …”
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6417
Improving the Quality of Total Hip Arthroplasty Operative Notes: A Clinical Audit Study
Published 2024-01-01“…A memory aid was then designed and placed in the operation room for two months, emphasizing the poorly documented aspects. …”
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6418
Triatoma venosa and Panstrongylus geniculatus challenge the certification of interruption of vectorial Trypanosoma cruzi transmission by Rhodnius prolixus in eastern Colombia.
Published 2025-01-01“…In this study, the aim was to describe the eco-epidemiological aspects of T. cruzi transmission in the rural area of Miraflores. For this, we designed a comprehensive, multi-faceted study in 6 rural villages and performed: (i) A cross-sectional serological and molecular study enrolling 155 people and 58 domestic dogs living within 80 households, (ii) a domestic entomological survey, (iii) a determination of the natural infection and blood meal source in collected triatomine bugs, and (iv) an evaluation of synanthropic mammal infection by parasitological and molecular tools. …”
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6419
Implementing curriculum at Sekolah Rimba Indonesia
Published 2024-12-01“…Through observation and analysis, this article explores how the Sekolah Rimba curriculum is designed to create a holistic and contextual learning environment. …”
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6420
Filtration and Breathability of Nonwoven Fabrics Used in Washable Masks
Published 2022-07-01“…Sets incorporating meltblown nonwoven polypropylene designed for filtration degraded significantly post-wash in the submicron range where they excelled prior to washing (Q > 50 kPa−1 at 1 µm, respectively, degraded to Q < 10 post-wash). …”
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