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741
Geometry optimization on the cross section of adhesively bonded thin-walled composite beam subjected to axial crushing load
Published 2024-03-01“…The non-dominated sorting genetic algorithm II (NSGA-II) was introduced to search for global optimum solution, and radial basis function (RBF) approximations for the objective functions were applied to reduce the computational cost. …”
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742
Autoimmune hepatitis: new in diagnostics, a pathogenesis and treatment
Published 2012-09-01“…AIH is a chronic inflammatory liver disease which is characterized by destruction of terminal plate by mononuclear infiltrate (interface hepatitis) according to histological investigation, hypergammaglobulinemia and production of autoantibodies. Genetic risk factors of AIH development is the presence of DRB1*0301 and DRB1*0401 alleles. …”
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743
The corpus callosum in people with congenital adrenal hyperplasia (CAH)
Published 2025-02-01“…Abstract Congenital Adrenal Hyperplasia (CAH) is a group of genetic disorders that affect the adrenal glands. …”
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744
A new species of Hemiphyllodactylus (Squamata, Gekkonidae) from western Yunnan, China
Published 2025-02-01“…The new species can be distinguished from its congeners by a significant genetic divergence of greater than 4.8% in the mitochondrial ND2 gene and a combination of the following characters: maximum SVL of 38.5 mm; 10 or 11 chin scales; enlarged postmentals; 6 circumnasal scales; 2 or 3 internasal scales; 8 or 9 supralabial scales; 8 or 9 infralabial scales; 15 or 16 dorsal scales; 9 ventral scales; a manual lamellar formula of 3-4-4-4 and a pedal lamellar formula of 3(4)-4-4-4; 26–28 precloacal and femoral pore-bearing scales contiguous in males; 1–3 cloacal spur on each side; a dark postorbital stripe extending to at least base of neck; dorsolateral light–colored spots on trunk present; dark ventrolateral stripe on trunk present; dark dorsal transverse blotches present; and a dark and brown postsacral mark bearing anteriorly projecting arms.…”
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745
Substantiation of application and estimation of efficacy of probiotics at inflammatory bowel diseases
Published 2015-05-01“…Microbiome changes result in initiation of cascade of pathological immune reactions of the host in related to presence of genetical defects, that, in turn, promotes development of clinical symptoms and morphological changes in intestinal wall. …”
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746
Enhancing Solar Energy Prospects: Predicting Direct Normal Irradiance in Qinghai Province Using ALO-RF Modeling
Published 2024-03-01“…Precise predictions facilitate the efficient assimilation of solar electricity into the electrical grid, augmenting energy production and maintaining system stability. This study uses the Genetic algorithm, Moth Flame Optimization, and Ant Lion Optimizer to optimize the Random Forest model. …”
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747
Bio-primed machine learning to enhance discovery of relevant biomarkers
Published 2025-02-01“…This method holds promise for advancing personalized medicine by uncovering novel therapeutic targets and understanding the complex interplay of genetic and molecular factors in disease.…”
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748
Kidney Diseases Classification using Hybrid Transfer-Learning DenseNet201-Based and Random Forest Classifier
Published 2023-01-01“…There are several disease kinds in global populations that may be related to human lifestyles, social, genetic, economic, and other factors related to the nature of the country they live in. …”
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749
How endocrine disruptors affect fish reproduction on multiple levels: A review
Published 2024-09-01“…Early-life exposure to these substances not only affects embryonic development, resulting in increased mortality and body malformations, but this also induces genetic changes in newly hatched larvae. All these observations underscore the need for monitoring the aquatic environment for EDCs and implementing protective measures to preserve the health and welfare of fishes and safeguard water ecosystems.…”
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750
The Shaping of New Ethnic Clusters in Kalmykia, 1957–1991
Published 2024-05-01“…The study employs the historical/comparative and historical/genetic methods to examine materials from the National Archive of Kalmykia, published documents and statistical tables, republican newspaper articles. …”
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751
A CACTA-like transposon in the Anthocyanidin synthase 1 (Ans-1) gene is responsible for apricot fruit colour in the raspberry (Rubus idaeus) cultivar 'Varnes'.
Published 2025-01-01“…In this investigation, we used a multi-omics approach to elucidate the genetic basis of the apricot fruit colour in raspberry. …”
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752
The emerging roles of aberrant alternative splicing in glioma
Published 2025-02-01“…Despite successful advances in understanding glioma, several genetic, epigenetic, and post-transcriptional alterations leave various targeted therapies ineffective, leading to a poor prognosis for high-grade glioma. …”
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753
Performance analysis of high-rate generalized space code index modulation system
Published 2025-01-01“…The traditional modulation symbols were replaced with the additional phase by the HR-GS-CIM system, and the genetic algorithm (GA) was used to optimize the design of the additional phase, which could acquire high energy efficiency advantage and performance advantage. …”
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754
Melanoma genomics – will we go beyond BRAF in clinics?
Published 2024-09-01“…Abstract In the era of next-generation sequencing, the genetic background of cancer, including melanoma, appears to be thoroughly established. …”
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755
Faking the News: Intentional Guided Variation Reflects Cognitive Biases in Transmission Chains Without Recall
Published 2018-07-01“…While copying error is directly analogous to genetic mutation, guided variation is a specifically cultural process that does not have a close parallel in biological evolution. …”
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756
Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade
Published 2025-02-01“…Our approach involved the use of genetic engineering to the long-lasting production of PD-1 and the brain-specific peptide angiopep-2 on the surface of EVs. …”
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757
Immunosuppressants in modern approaches to treatment of inflammatory bowel diseases
Published 2013-05-01“…There is no need of study for genetic mutations before prescription of thiopurines, however application of effective methods of evaluation of prognosis of bone marrow toxicity development remains an actual issue. …”
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758
The ethics of theft: Reevaluating the impacts of floral larceny on plant reproductive success
Published 2025-01-01“…By altering pollinator behavior, floral larceny may reduce geitonogamy, potentially enhancing genetic diversity. Additionally, factors such as pollinator type, plant mating system, and pollen limitation were identified as key moderators of these effects. …”
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759
Challenges in Diagnosing Intrahepatic Cholangiolithiasis in a 39-Year-Old Patient
Published 2024-12-01“…Cholangiolithiasis occurs in more than half of cases of primary sclerosing cholangitis and can be both a complication and a cause of secondary sclerosing cholangitis, maintaining inflammation in the ducts and facilitating stone formation. Genetic mutations are known to contribute to the development of gallstones in young patients, including low phospholipid-associated cholelithiasis. …”
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760
Vitamin D and Selenium: Review of Clinical Trials of Synergistic Effects on Thyroid Antibody Levels and Disease Progression in Hashimoto’s Thyroiditis
Published 2025-02-01“… Introduction: Hashimoto's Thyroiditis (HT) is a common autoimmune thyroid disorder caused by genetic predispositions and environmental factors, such as iodine imbalance, selenium deficiency, and stress. …”
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