Developing an instrument to measure the quality of social work cancer counseling regarding return to work — psychometric properties of the German Quality of Cancer Counseling Quest... by Clara Breidenbach, Sabine Schneider, Marie Rösler, Nicole Ernstmann, Paula Heidkamp, Lina Heier, Kati Hiltrop, Sophie Schellack, Johannes Soff, Johanna Weiss, Christoph Kowalski

“…It is an evaluation tool specific for cancer counseling regarding return to, since it will initially be used to evaluate an intensified program for supporting cancer survivors returning to work after treatment. …”
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Theranostic nanoemulsions suppress macrophage-mediated acute inflammation in rats by Riddhi Vichare, Yalcin Kulahci, Rebecca McCallin, Fatih Zor, Fatma Nurefsan Selek, Lu Liu, Caitlin Crelli, Anneliese Troidle, Michele Herneisey, James M. Nichols, Andrew J. Shepherd, Vijay S. Gorantla, Jelena M. Janjic

“…Macrophages are immune cells that contribute to the initiation, maintenance, and resolution of inflammation due to their phenotypic plasticity in response to signals from inflammatory microenvironments. …”
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Standardization and validation of a novel reverse transcriptase polymerase chain reaction method for detecting virulent strains of the infectious bursal disease virus by Vladimir Longa-Bobadilla, Phillip Ormeño-Vásquez, Manuel Criollo-Orozco, Luis Tataje-Lavanda, Katherine Huamán-Gutierrez, Ángela Montalván, Mirko Zimic, Manolo Fernández-Sanchez, Manolo Fernández-Díaz

“…Conclusion: Our novel RT-PCR procedure has been demonstrated to be helpful in selectively amplifying the consensus sequence of the VP5 gene, indicating that this novel RT-PCR procedure constitutes an important and useful tool to execute initial discrimination of field-retrieved samples containing and not containing virulent strains of this virus before deciding to execute a blindly and more costly sequencing procedure of all the samples together.…”
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Real-world enrollment for a prospective clinico-genomic database using a pragmatic technology-enabled platform by Alexia Exarchos, Ariel B. Bourla, Maneet Kaur, Katja Schulze, Sophia Maund, Yi Cao, Yihua Zhao, Elizabeth H. Williams, Sarah C. Gaffey, Richard Zuniga, Shaily Lakhanpal, Vladan Antic, Michelle Doral, Johanna Sy, Neal J. Meropol, Anne C. Chiang

“…Methods: Adults with stage IV or recurrent metastatic non-small cell lung cancer or extensive-stage small-cell lung cancer were enrolled at 23 US sites upon initiating a standard line of therapy. Enrollment rates were estimated from eligible populations at individual centers. …”
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Rationale and design for Healthy Hearts in Manufacturing (HHM): A pragmatic single-arm hybrid effectiveness-implementation study for hypertension management and tobacco cessation by Hanzi Jiang, Yao Tian, Jennifer Bannon, Amy E. Krefman, Lawrence C. An, Dustin D. French, Claude R. Maechling, Jane Holl, Richard Chagnon, Theresa L. Walunas, Christopher Burch, Anthony Musci, Darce Latsis, Dawn Carey, Megan McHugh

“…The HHM intervention involves monthly coaching to assist WHCs with implementing evidence-based strategies for hypertension management and tobacco cessation advocated by the Million Hearts initiative and the U.S. Preventive Services Task Force. …”
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Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders by Fancheng Liu, Fancheng Liu, Yazhen Su, Yazhen Su, Xinling Liu, Li Zhao, Li Zhao, Zewen Wu, Zewen Wu, Yang Liu, Yang Liu, Liyun Zhang, Liyun Zhang

“…Elevated concentrations of cfDNA are recognized by DNA receptors, initiating immune-inflammatory reactions which subsequently accelerate the progression of disease. …”
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H. pylori-Associated Gastritis, Gastritis after H. pylori Eradication and H. pylori-Negative Gastritis: Algorithm of Diagnosis and Treatment (Literature Review and Resolution of... by V. T. Ivashkin, I. V. Maev, T. L. Lapina, Yu. A. Kucheryavyy, S. R. Abdulkhakov, O. P. Alekseeva, S. A. Alekseenko, D. N. Andreev, I. G. Bakulin, N. V. Bakulina, D. S. Bordin, Z. M. Galeeva, N. N. Dekhnich, N. V. Korochanskaya, R. O. Kuvaev, M. A. Livzan, M. F. Osipenko, S. S. Pirogov, V. I. Simanenkov, O. A. Storonova, A. S. Tertychnyy, A. S. Trukhmanov, Yu. P. Uspenskiy, I. B. Khlynov, V. V. Tsukanov

“…Members of the Expert Panel has approved the algorithm of diagnosis and treatment of H. pylori-associated gastritis, gastritis after H. pylori eradication and H. pylori-negative gastritis at the diagnostic stage in the case of initial presentation and long-term follow-up when needed.…”
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Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease by Yue Xu, Yue Xu, Durong Chen, Meiqi Dong, Yun Zhang, Yun Zhang, Hongmei Yu, Hongmei Yu, Hongmei Yu, Yanqing Han, Yanqing Han, Yanqing Han

“…ObjectiveTo investigate the bidirectional relationship between depression and activities of daily living (ADL) in Parkinson’s disease (PD) patients and explore the mediating role of cognitive function over time.MethodsData from 892 PD patients from the Parkinson’s Progression Markers Initiative (PPMI) database were included in this study, and depression, cognitive function, and ADL were measured using the Geriatric Depression Scale (GDS-15), Montreal Cognitive Assessment Scale (MoCA), and Unified Parkinson’s Disease Rating Scale, Part II (UPDRS II) respectively. …”
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Optimising Access Surgery in Senior Haemodialysis Patients (OASIS): study protocol for a multicentre randomised controlled trial by Patrick WHE Vriens, Edith M Willigendael, Maarten A Lijkwan, Friedo W Dekker, Chava L Ramspek, Michiel W de Haan, Çaĝdaş Ünlü, Boudewijn DC Heggen, Koen E A van der Bogt, Marc H Hemmelder, Mickaël J C Hiligsmann, Magda M van Loon, Joris I Rotmans, Jan H M Tordoir, Geert Willem H Schurink, Maarten G J Snoeijs, Marijke J Molegraaf, Philippe WM Cuypers, Denise Nio, Cora H Arts, Jacobien C Verhave, Goos D Laverman, Aron S Bode, Marcel C Weijmer, Bas Govaert, Aaltje Y Adema, Gijs MJM Welten, Michel MPJ Reijnen, Marc JH Groeneveld, Hans S Brink, Jeroen B van der Net, Arno Kuijper, Hilde PE Peters, Roos C van Nieuwenhuizen, Rombout R Kruse, Yvonne C Schrama, Karina A de Groot, Karima Farhat

“…Patients aged 70 years or older who are expected to initiate haemodialysis treatment in the next 6 months or who have started haemodialysis urgently with a catheter will be enrolled. …”
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Pre-diagnostic risk factors for brain cancer incidence and survival: insights from the Golestan Cohort Study by Parisa Rezanejad-Asl, Peyvand Parhizkar Roudsari, Negar Rezaei, Maryam Sharafkhah, Gholamreza Roshandel, Hossein Poustchi, Sadaf Sepanlou, Reza Malekzadeh

“…Further research is mandated to inform policy makers of potentially effective preventive initiatives to reduce the burden of this cancer.…”
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Optimization and potential assessment of CO2 geological storage caprock in the saline aquifers of the Qingjiang Basin, middle and lower reaches of the Yangtze River by Yuchen Tian, Shiqi Liu, Sijian Zheng, Shuxun Sang, Yinghai Liu, Shiheng Chen, Helong Zhang, Yanzhi Liu, Yuntian Jiang, Zekun Yue, Wenkai Wang

“…A study was conducted in response to the geological characteristics of the Qingjiang Basin to optimize caprock for CO2 geological storage in saline aquifers and assess its potential. The research initially outlined the regional geological background of the Qingjiang Basin, including its tectonic position, stratigraphic distribution, sedimentary features, and the division of secondary structural units. …”
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Efforts to strengthen anatomic pathology diagnostic services for cancer in sub-Saharan Africa: a scoping review protocol by Katherine Van Loon, Elia John Mmbaga, Marcia Edelweiss, Dianna L. Ng, Asteria Herman Kimambo, Edda Vuhahula, Beatrice Paul Mushi, Omolade Adegoke, Johanna Goldberg, Pendo M. Ibrahim, Zainab Illonga, Julia Jackman, Luisa Jamisse

“…The primary aim of the scoping review is to comprehensively map the existing evidence on initiatives aimed at enhancing the capacity for pathology services.Methods and analysis This study will follow Joanna Briggs Institute methodology for scoping reviews. …”
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Implementation of model-informed precision dosing for tamoxifen therapy in patients with breast cancer: A prospective intervention study by Ruben Y.M. van Nijnatten, Sanne M. Buijs, Bram C. Agema, Raphaël M.J. Fischer, Inge Ghobadi Moghaddam-Helmantel, Caroline M.E. Contant, Felix E. de Jongh, Auke M.T. Huijben, Manon Kop, Annemieke van der Padt-Pruijsten, Hanneke J.M. Zuetenhorst, Ron H.N. van Schaik, Birgit C.P. Koch, A. Jager, Stijn L.W. Koolen, Ron H.J. Mathijssen

“…Endoxifen samples that were acquired 4–6 weeks after treatment initiation, are informative of steady-state endoxifen levels and can be used to inform MIPD and adjust tamoxifen dosing prior to steady-state attainment.In this first MIPD implementation study for patients treated with tamoxifen, MIPD did lead to more patients achieving endoxifen levels ≥16 nM as compared to the one-dose-fits-all strategy, albeit insignificant. …”
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Dosimetry of automatic non-coplanar volumetric-modulated arc therapy for nasopharyngeal carcinoma by Kaiqiang Chen, Jihong Chen, Yanming Cheng, Danni Hong, Cairong Hu, Penggang Bai, Jinyong Lin, Yang Yang, Xiuchun Zhang

“…Methods: A retrospective analysis was conducted on 20 patients with initially diagnosed NPC who had received TomoTherapy (TOMO) treatment. …”
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Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer by Paola Zagami, Angela Esposito, Beatrice Taurelli Salimbeni, Pier Paolo Maria Berton Giachetti, Roberta Scafetta, Matteo Lambertini, Massimo Di Maio, Giuseppe Curigliano, Carmen Criscitiello, Saverio Cinieri

“…The oncologists prescribing CDK4/6i switch reported that most of these patients were in first line treatment (85 %) and the most common second CDK4/6i most frequently initiated was palbociclib (69 %), then abemaciclib (17 %) and ribociclib (14 %). …”
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Validation of the Transition Readiness and Appropriateness Measure (TRAM) for the Managing the Link and Strengthening Transition from Child to Adult Mental Healthcare in Europe (MI... by Fiona McNicholas, Dieter Wolke, Jason Madan, Jatinder Singh, Federico Fiori, Paramala Santosh, Jane Warwick, Helena Tuomainen, Swaran Singh, Laura Adams, Mathilde Mastroianni, Natalie Heaney, Kate Lievesley, Ilyas Sagar-Ouriaghli, Giovanni Allibrio, Rebecca Appleton, Nikolina Davidović, Giovanni de Girolamo, Gwen Dieleman, Katarina Dodig-Ćurković, Tomislav Franić, Charlotte Gatherer, Suzanne Gerritsen, Elisa Gheza, Lidia Manenti, Athanasios Maras, Francesco Margari, Adriana Pastore, Moli Paul, Diane Purper-Ouakil, Francesco Rinaldi, Vehbi Sakar, Ulrike Schulze, Giulia Signorini, Cathy Street, Priya Tah, Sabine Tremmery, Amanda Tuffrey, Frank Verhulst, Anna Wilson

“…To improve this state of affairs, there needs to be a recognition of the problem and initiatives and an urgent requirement for appropriate tools for measuring readiness and outcomes at the transfer boundary (16–18 years of age in Europe). …”
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A retrospective analysis of outcomes and complications of living- and deceased-donor split-liver transplantation in Johannesburg, South Africa by R Crawford, J Loveland, P Gaylard, J Fabian, K Kinandu, B Bobat, A Mahomed, D Parbhoo, M Beretta, S Berkenfeld, S Rambarran, F van der Schyff, L Brannigan, B Strobele

“…To increase organ utility, deceased-donor split-liver transplant (DDSLT) and living-donor liver transplant (LDLT) programmes were initiated in the Wits Transplant Unit. Objective. …”
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Wind Field Retrieval From Co-Polarized SAR Imagery Without External Wind Direction Assistance by Xianen Wei, Jinsong Chong, Yawei Zhao, Lijie Diao, Xuan Jin

“…This method underwent testing with Sentinel-1 Stripmap co-polarized SAR images in wind field retrieval experiments. Four cases were initially conducted to demonstrate the effectiveness of the proposed method in both downwind and upwind scenarios. …”
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A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda by Keneth Iceland, Kasozi, Anne, Laudisoit, Lawrence Obado, Osuwat, Gaber El-Saber, Batiha, Naif E. Al, Omairi, Eric, Aigbogun, Herbert Izo, Ninsiima, Ibe Michael, Usman, Lisa M., DeTora, Ewan Thomas, MacLeod, Halima, Nalugo, Francis P., Crawley, Barbara E., Bierer, Daniel Chans, Mwandah, Charles Drago, Kato, Kenedy, Kiyimba, Emmanuel Tiyo, Ayikobua, Linda, Lillian, Kevin, Matama, Shui Ching, Nelly Mak, David, Onanyang, Theophilus, Pius, Linda, Lillian, Kevin, Matama, Shui Ching, Nelly Mak, David, Onanyang, Theophilus, Pius, David Paul, Nalumenya, Robinson, Ssebuufu, Nina Olivia, Rugambwa, Grace Henry, Musoke, Kevin, Bardosh, Juma John, Ochieng, Fred, Ssempijja, Patrick, Kyamanywa, Gabriel, Tumwine, Khalid J., Alzahrani, Susan Christina, Welburn

“…There is a need to increase transparency and inclusive participation to address these issues before new trials of COVID-19 vaccines are initiated…”
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Patterns of failure and prognosis in nasopharyngeal carcinoma according to Epstein-Barr virus DNA status by Lin-Feng Guo, Guan-Zhong Lu, Zhen-Zhen Lu, Yi-Feng Yu, San-Gang Wu

“…Results This study involved 108 patients, including 105 (97.2%) who had EBV-DNA detectable at the initial diagnosis of NPC. Regarding progression patterns, 34 patients (31.5%) experienced only LRR, while 60 patients (55.6%) had only DM. …”
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