A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in... by Thomas R. Moench, Lakshmi Botta, Brian Farrer, Jason D. Lickliter, Hyunah Kang, Yoona Park, Cheolmin Kim, Marshall Hoke, Miles Brennan, Morgan D. McSweeney, Zachary Richardson, John B. Whelan, Jong Moon Cho, Soo Young Lee, Frances Faurot, Jeff Hutchins, Samuel K. Lai

“…Geometric mean nasal fluid concentrations of IN-006 in the multiple dose cohort were 739.8 μg/mL at 30 min after dosing and 1.2 μg/mL at 22 h. …”
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Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury by Luying Zhang, Song Yang, Hao Cui, Chenchen Hang, Xingsheng Wang, Le An, Zhenyu Shan, Zhen Liang, Rui Shao, Ziren Tang

“…Mitochondrial membrane potential (MMP) and mitochondrial permeability transition pore (mPTP) opening were determined respectively by JC-1 staining and BBcellProbe M61 staining using a flow cytometer. …”
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The physiological responses to volume-matched high-intensity functional training protocols with varied time domains by Jessica S. Smith, Jessica S. Smith, Gabriella F. Bellissimo, Gabriella F. Bellissimo, Fabiano T. Amorim

“…There were significant differences between the EMOM and RFT for HR (153 ± 19 bpm vs. 171 ± 12 bpm, p < 0.01), VO2 (30.8 ± 3 mL/kg/min vs. 38.1 ± 5 mL/kg/min, p < 0.00), RPE (4 ± 1 vs. 7 ± 1, p < 0.00), and EPOC-AUC (3.5 ± 1.2 mL/kg/min vs. 5.0 ± 1.3 mL/kg/min, p < 0.00); however, there were no significant differences in mean SmO2 (p = 0.44). …”
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Penerapan Metode Weighted Product untuk Seleksi Kelulusan Santri pada Sistem Informasi Wisuda Taman Pendidikan Al-Quran (TPA) Universitas Darussalam Gontor by Dihin Muriyatmoko, Triana Harmini, Muhamad Nuradi Arrahmantoro

“…Padahal menurut evaluasi para Ustadz dan kepala Lembaga Pengabdian kepada Masyarakat (LPkM) mestinya ujian Al-Quran menjadi prioritas utama. …”
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Comparison of different drying processes of Morchella sextelata: Changes in volatile and non-volatile components, color and texture by Yaxuan Liao, Mengdi Xin, Hao Dong, Yuxing Liu, Lingling Li, Xinyong Guo, Shaobo Cheng, Guogang Chen

“…In this study, the effects of hot-air drying (HAD), hot-air combined microwave vacuum drying (HAD-MVD), vacuum freeze drying (VFD), and natural drying (ND) on the color, textural properties, microstructure, non-volatile substances, and volatile flavor compounds of the Morchella sextelata (M. sextelata) mushroom were investigated. The results showed that VFD best maintains the color, texture, and flavor of M. sextelata, while HAD-MVD yields dehydrated M. sextelata having a color and dense cellular microstructure similar to that achieved with VFD but in less time. …”
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Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial by Xiaoyang Hong, Yongjian Guo, Wenbo Shi, Kangshun Zhu, Licong Liang, Liteng Lin, Ye Chen, Jingwen Zhou, Jingjun Huang, Jiabai Huang, Yaozhu Wu, Wensou Huang, Mingyue Cai

“…The objective response rate was 23.3% per mRECIST and 16.7% per RECIST 1.1, while the disease control rate reached 76.7% per mRECIST/RECIST 1.1. …”
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المقدمة والغلاف

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The theses for MD degree by article Editorial

“…M.D. Mikhailova — Gastroesophageal reflux disease: comparative efficacy of non-pharmacological and pharmacological treatments.…”
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Microbiome role in pancreatic diseases development by Yu. V. Evsyutina, V. T. Ivashkin

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Clinical and Pathogenetic Parallels of Nonalcoholic Fatty Liver Disease and Gallstone Disease by Aleksey O. Bueverov

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Inflammatory Bowel Diseases and Irritable Bowel Syndrome: Overlap of Two Nosological Forms or Two Variants of the Same Disease? by A. A. Sheptulin, K. E. Vinogradskaya

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Clinical presentation, diagnosis and treatment of intrahepatic cholestasis of pregnancy by Yu. B. Uspenskaya, A. A. Sheptulin

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Liturgia jako consummatio fidei by Marcel Mojzeš

“… W dzisiejszej konsumpcyjnej społeczności bardzo ważne jest rozumienie pojęcia consummatio (przez dwa „m”) nie jako skonsumowanie (łac. consumatio z jednym „m”), lecz jako dokonanie, dokończenie, wypełnienie. …”
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Intestinal microbiome as effective regulator of enteral and central nervous system activity by V. T. Ivashkin, K. V. Ivashkin

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A review of COVID-19 vaccination and the reported cardiac manifestations by Jamie Sin Ying Ho, Ching-Hui Sia, Jinghao Nicholas Ngiam, Poay Huan Loh, Nicholas Wen Sheng Chew, William Kok-Fai Kong, Kian-Keong Poh

“…In Singapore, 9.03 million doses of the mRNA COVID-19 vaccines by Pfizer-BioNTech and Moderna have been administered, and 4.46 million people are fully vaccinated. …”
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Occupancy of the highly categorized accommodation related to the changed conditions of demand: The example of the municipality of Vrnjačka Banja by Mladenović Dejan, Popović Ivana

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Effect of body mass index on inpatient rehabilitation outcome after stroke in a Southeast Asian cohort: a prospective study by Sze Chin Jong, Jovic Aguipo Fuentes, Angie En Qin Seow, Chien Joo Lim, Gobinathan Chandran, Karen Sui Geok Chua

“…Using the World Health Organization Asian standards, BMI was classified as underweight (<18.5 kg/m2), normal (18.5–22.9 kg/m2) and overweight (≥23 kg/m2). …”
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Cobalt titanate nanocatalyst for enhanced photodegradation of atrazine: kinetics, degradation efficiency, and mechanistic analysis by Jeremiah Suleiman Nuhu, Femi Emmanuel Awe, Rajni Garg, Rishav Garg, Nnabuk Okon Eddy, Hazratullah Paktin

“…The synthesized nanoparticles exhibited a surface area of 32.5 m2/g (DFT) and 828.03 m⁻1 (BET), a pore volume of 0.03925 m3/g, and a bandgap energy of 2.66 eV. …”
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