Economic evaluation of encorafenib with cetuximab in patients with BRAF V600E-mutant metastatic colorectal cancer in France: a cost-effectiveness analysis using data from the BEACO... by David Malka, Philippe Laramée, Mondher Toumi, Jean-Baptiste Trouiller, Bérengère Macabeo, Andrew Poll, Dan Howard, Andy Buckland, Marine Sivignon, Emilie Clay, Emmanuelle Samalin

“…Objective The BEACON CRC randomised controlled trial (NCT02928224) in BRAF-mutant metastatic colorectal cancer (mCRC) patients showed improved overall survival for the combination treatment of encorafenib (BRAF inhibitor) with cetuximab (EGFR inhibitor) compared with cetuximab with chemotherapy (FOLFIRI (folinic acid, fluorouracil and irinotecan) or irinotecan). …”
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Impacts of coal fracture roughness and aperture on the seepage of injected water: An experimental study by Gang WANG, Xuechang CHEN, Hao CHEN, Qingming LONG, Yixin LIU

“…As the fracture aperture increased from 30 μm to 150 μm, the seepage rate of fractures increased 355.88 times at most. …”
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Maternal and Perinatal Outcomes of Pregnancies with Uterine Leiomyomas by Caner Kose, Busra Korpe, Tugba Kinay, Seval Yilmaz Ergani, Rahmi Sinan Karadeniz, Ali Turhan Caglar, Yaprak Engin Ustun

“…The amount of blood loss (969.66±427.21 mL vs. 738.15±337.2 mL and 553.84±366.46 mL), duration of surgery (83.23±29.56 min vs. 64.47±17.96 min) and transfusion requirements (36% vs. 5.3% and 28.8%) were higher in women who underwent myomectomy during cesarean section than in the other women undergoing only cesarean section or delivering vaginally (p<0.05). …”
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Volatile Organic Compounds and Carbonyls Pollution in Mexico City and an Urban Industrialized Area of Central Mexico by Elizabeth Vega, Omar Ramírez, Gabriela Sánchez-Reyna, Judith C. Chow, John G. Watson, Diego López-Veneroni, Monica Jaimes-Palomera

“…The highest concentrations were found for formaldehyde at 87.2 µg m−3, followed by acetaldehyde (52.1 µg m−3) and acetone (49.7 µg m−3), accounting for 96% of the total carbonyls in Tula. …”
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Improving the survival under gastric conditions of a potential multistrain probiotic produced in co-culture by Marcelo Fernando Valle-Vargas, Yesica Vanesa Rojas-Muñoz, Ruth Yolanda Ruiz-Pardo, Luisa Villamil-Díaz, María Ximena Quintanilla-Carvajal

“…As the main result, a high concentration of di-sodium phosphate (2.63% w/v) increased the viability of L. lactis A12 (9.05 to 9.46 Log10 CFU/mL) and Priestia species (0.00 to 6.88 Log10 CFU/mL), survival to pH 3.00 (60 to 93%), survival of bile salts (58– 93%) antagonistic activity (8.74 to 15.56 mm), and final pH of culture medium (4.34 to 6.95). …”
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Distribution and Main Influencing Factors of Net Ecosystem Carbon Exchange in Typical Vegetation Ecosystems of Southern China by Yike Wang, Xia Liu, Weijia Lan, Shuxian Yin, Liya Fan, Boru Mai, Xuejiao Deng

“…The results showed that (1) the NEE of ECFEs was highest in winter and lowest in summer, with an annual average of –4.21 ± 0.44 μmol m-2 s-1. The NEE values of TCMEs and CCEs were comparable and significantly lowerthan that in ECFEs, with annual average NEE values of –1.96 ± 0.09 μmol m-2 s-1 and –1.98 ± 0.04 μmol m-2 s-1, respectively. …”
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Smartphone overuse and distraction: which relationship with general well-being across different generations? by Diego Bellini, Maria Lidia Mascia, Rachele Conti, Maria Pietronilla Penna

“…These groups included Baby Boomers (M = 63.76; SD = 4.50), Generation X (M = 50.94; SD = 4.41), Generation Y (35,88; SD = 2.29), and Generation Z (M = 24.23; SD = 2.73). …”
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Comparison of chemical constituents in Lysimachia species and their antimicrobial activity for extending the shelf life of foods by Li-Li Chen, Shuang Long Yang, Ji-Cun Bao, Wei-You Xie, Zhao-Chan Wang, Nian Shi, Zhao-Jie Wang

“…The KBZZC-05, 21, and 23 inhibited both spoilage organisms and foodborne pathogens (MICs = 2–256 μg/mL) better than potassium sorbate (MIC >256 μg/mL). …”
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Laserpuncture Shooting Duration Effect at the Growth Point on the Weight Gain and Growth Rate of Male Japanese quail (Coturnix coturnix japonica) by Aida Zharah, Sri Hidanah, Yeni Dhamayanti, Sunaryo Hadi Warsito, R Tatang Santanu Adikara, Gracia Angelina Hendarti

“…Group P1 was treated by laserpuncture every day with power supply at 50 mWatt and the dose was 0.2 Joule for 5 seconds. …”
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A COMPARATIVE STUDY ON THE EFFECT OF SISAL FIBRE AND WASTE PLASTIC STRIPS IN STRUCTURAL STRENGTH IMPROVEMENT OF TROPICAL BLACK CLAY by YOHANNA PAUL, BADAMASI ABDULRAHMAN, ISHOLA KAZEEM, ODOH KELVIN CHUKWUEBUKA, ABDULKADIR MOHAMMED NYAKO, FWANGSHAK GAYUS MIJE

“…Maximum dry density (MDD) initially increased from 1.55 mg/m3 at 0%, to 1.60 mg/m3 at 0.5% and thereafter decreased to 1.53 mg/m3 at 2% of fibre content. …”
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Diversity and Conservation Status of Large Mammals in Ghamot National Park, Azad Jammu and Kashmir, Pakistan by Muhammad Jahangeer, Siddique Muhammad, Muhammad Shakeel, Mir Muhammad Saleem, Ali Usman, Hussain Abid

“…The Scrubland zone had the most indirect evidences (n=37) of any zone (elevation ranges between 2600-3600m).The forest zone (elevation ranges between 2700-3450m) had the second highest sampling (n=28), followed by the Alpine Zone (n=28), Riparian Zone (n=21), and Alpine Pasture Zone (n=16) (elevation 4000-4400m; habitat type high alpine pastures). …”
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Helicobacter pylori CagA+ strains modulate colorectal pathology by regulating intestinal flora by Shasha Cui, Xinqiang Liu, Fengxia Han, Lu Zhang, Jingjing Bu, Sainan Wu, Jiafen Wang

“…Method 6-week C57BL/6J mice were divided into: (a) HP CagA+ group undergoing HP CagA+ strains administration by gavage at 0.2 mL for 10 days; (b) HP CagA- group undergoing HP CagA- strains administration by gavage at 0.2 mL for 10 days; (c) control group intragastrically given 0.2 mL of brian heart infusion (BHI) medium for 10 days. …”
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Gonadal aspects, testosterone and estradiol profiles of the Lebranche mullet Mugil liza subjected to different temperatures during the larviculture phase by Marco Shizuo Owatari, Vanessa Martins da Rocha, Cleize Sales da Silva, Marina Cesconeto dos Santos, Mariana Rangel Pilotto, Fabiola Santiago Pedrotti, Caio Magnotti, Maurício Laterça Martins, Vinicius Ronzani Cerqueira

“…In summary, the results provide evidence that temperature may play a crucial role in sex determination in M. liza. …”
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Frequency of television viewing and association with overweight and obesity among women of the reproductive age group in Myanmar: results from a nationwide cross-sectional survey by Rajat Das Gupta, Ibrahim Hossain Sajal, Mehedi Hasan, Ipsita Sutradhar, Mohammad Rifat Haider, Malabika Sarker

“…Objectives This study aimed to discern the association between the frequency of television viewing and overweight and obesity among reproductive age women of Myanmar.Design This was a cross-sectional study.Setting This study used Myanmar Demographic and Health Survey (2015–2016) data.Participants Total of 12 021 women both aged 15–49 years and also not pregnant or did not deliver a child within the 2 months prior to the survey were included.Primary and secondary outcome measures The primary outcome was overweight (23.0 kg/m2 to &lt;27.5 kg/m2) and obesity (≥27.5 kg/m2), which was measured using the Asian body mass index cut-off. …”
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Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial by Alison Griffiths, Simon Shohet, Neil Johnson, Alasdair MacCulloch

“…There were few patients in PROPEL who could walk ≤75 m at any time point in the study, hence, these utility estimates should be interpreted with caution. …”
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Out-of-field dose assessment for pencil beam scanning proton radiotherapy versus photon radiotherapy for breast cancer in pregnant women by Menke Weessies, Murillo Bellezzo, Britt J.P. Hupkens, Frank Verhaegen, Gloria Vilches-Freixas

“…Results: At 20 weeks, PBS-PRT including imaging delivered 22.4 mSv, reducing dose 3.4-fold versus 6FF XRT and 2.5-fold versus 6FFF XRT. …”
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Beyond Hormone Receptors: liquid biopsy tools to unveil new clinical meanings and empower therapeutic decision-making in Luminal-like metastatic breast cancer by Brenno Pastò, Riccardo Vida, Arianna Dri, Lorenzo Foffano, Serena Della Rossa, Lorenzo Gerratana, Fabio Puglisi

“…Immunohistochemical (IHC) tissue profiling is a standard practice in the management of metastatic breast cancer (mBC), that enables the identification of distinct biological phenotypes based on hormone receptors' expression. …”
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Effect of phycocyanin and phycoerythrin on antioxidant and antimicrobial activity of refrigerated low-fat yogurt and cream cheese by Azadeh Ahmadi, Seyed Amir Ali Anvar, Bahareh Nowruzi, Leila Golestan

“…Additionally, we confirmed that PE and PC are not toxic to Caenorhabditis elegans at concentrations up to 1 mg/mL. The results showed that the MIC of PE and PC against E. coli was significantly higher than against S. aureus (3.12 ± 0.05 µg/mL vs. 1.56 ± 0.01 µg/mL, respectively; p ≤ 0.05). …”
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Non-Alcoholic Fatty Liver Disease in Cardiac Patients with Overweight and Obesity by I. V. Logacheva, T. A. Ryazanova, V. R. Makarova, O. V. Surnina

“…The patients were divided into 3 groups according to their body mass index (BMI): 29 men with a BMI under 25 kg/m2(I group); 43 overweight men a BMI over 25 of kg/m2(II group); 40 men with obesity and a BMI above 30 of kg/m2(III group). …”
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Nutritional, physicochemical, and antioxidant characterization of pomegranate, beetroot, and carrot concentrates supplemented functional whey beverages by Muhammad Saleem, Zulfiqar Ahmad, Muhammad Waseem, Tawfiq Alsulami, Muhammad Rizwan Javed, Muhammad Farhan, Gulzar Ahmad Nayik, Muhammad Faisal Manzoor, Gholamreza Abdi

“…The highest TPC (27.3 mg GAE/100 mL), TFC (13.3 mg QE/100 mL), DPPH (41 %), and FRAP (101.3 μmol TE/100 mL) were found in PCWb than BCWb and CCWb. …”
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