Isolated tubercular dacryoadenitis in a non-immunocompromised healthy adult by Ajax Jossy, N Kaviyapriya, Nirupama Kasturi, Sree J Rekha

“…A middle-aged woman presented with a slowly enlarging mass in the right superotemporal orbit and ptosis. …”
Get full text

A case of thymoma presenting as pyrexia of unknown origin by Vikas Marwah, Robin Choudhary, V Shrinath, Gourang Paliwal

“…We report an interesting case of a middle-aged male who presented as pyrexia of unknown origin due to thymoma.…”
Get full text

Age-related changes in brain signal variability in autism spectrum disorder by Priyanka Sigar, Nicholas Kathrein, Elijah Gragas, Lauren Kupis, Lucina Q. Uddin, Jason S. Nomi

“…The group × quadratic age interaction showed significant differences in the brain regions included in DMN, with an inverted U-shaped rMSSD-age relationship in ASD (higher rMSSD in younger individuals that slightly increased into middle age before decreasing) and a U-shaped rMSSD-age relationship in TD (higher rMSSD in younger and older individuals compared with middle-aged individuals). …”
Get full text

The relationship between walking speed and changes in cardiovascular risk factors during a 12-day walking tour to Santiago de Compostela: a cohort study by Frank L J Visseren, Yolanda van der Graaf, Wilko Spiering, Remy H H Bemelmans, Paulus P Blommaert, Annemarie M J Wassink, Blai Coll

“…We report the relationship between walking speed and changes in cardiovascular risk factors in participants of a 12-day walking tour to Santiago de Compostela.Design Prospective cohort study.Setting Single-centre study with healthy middle-aged volunteers.Participants Healthy middle-aged men (n=15) and women (n=14). …”
Get full text

Systemic immune-inflammation index mediates the association between abdominal obesity and serum klotho levels by Chenchun Chen, Peng Tang, Wei Zhu

“…A cross-sectional study was conducted using data from 6997 middle-aged and elderly Americans participating in the National Health and Nutrition Examination Surveys (NHANES) between 2011 and 2016. …”
Get full text

Pancreatic tuberculosis mimicking as pancreatic malignancy: Surgeon's dilemma by Rohik Anjum T. Siddeek, Amit Gupta, Tanuj Singla, Deepak Rajput, Shaik Sameer Ahmed, Reshma Jeladharan

“…Here, we report a case of middle-aged gentleman presenting with abdominal pain and constitutional symptoms who was diagnosed with pancreatic tuberculosis on imaging, which was confirmed by Fine Needle Aspiration (FNA) from the lesion. …”
Get full text

Age Groups and Generations: Lines of Conflict and Potentials for Integration by Martin Kohli

“…In terms of economic well-being, both the young and the old fare worse than the middle age group. In terms of political decision-making, there is no evidence for an alleged movement towards gerontocracy.…”
Get full text

Serum Carboxy-terminal Cross-linking Telopeptide Fragments of Type-2 Collagen Level in the General Population: A Pilot Study by Rajat Khanna, Divyam Jindal, Sudhir Singh

“…Aim: The aim of this study was to determine the serum carboxy-terminal cross-linking telopeptide fragments of type-2 collagen (sCTX-II) level in normal healthy young and middle-aged individuals. Materials and Methods: Normal healthy adults were included as the participants in this study (175 participants). …”
Get full text

Effect of the intrinsic and extrinsic factors on the growth and development of young foals under subtropical conditions of Pakistan. by Muhammad Athar Chatha, Nisar Ahmad, Muhammad Athar Abbas, Muhammad Saadullah, Jawaria Ali Khan

“…Extreme winter conditions were associated with a notably lower survival probability (P = 0.002), and middle-aged dams exhibited significantly enhanced survival odds (P = 0.03). …”
Get full text

Obesity phenotypes and dyslipidemia in adults from four African countries: An H3Africa AWI-Gen study. by Engelbert A Nonterah, Godfred Agongo, Nigel J Crowther, Shukri F Mohamed, Lisa K Micklesfield, Palwendé Romuald Boua, Alisha N Wade, Solomon S R Choma, Hermann Sorgho, Isaac Kissiangani, Gershim Asiki, Patrick Ansah, Abraham R Oduro, Shane A Norris, Stephen M Tollman, Frederick J Raal, Marianne Alberts, Michele Ramsay, as members of AWI-Gen and the H3Africa Consortium

“…<h4>Introduction</h4>The contribution of obesity phenotypes to dyslipidaemia in middle-aged adults from four sub-Saharan African (SSA) countries at different stages of the epidemiological transition has not been reported. …”
Get full text

Acute Intestinal Obstruction due to Complicated Meckel’s Diverticulum in an Adult: A Case Report by Arundhati Negi, Geofia Shaina Crasta, Bharath Kumar Bhat

“…MD causing intestinal obstruction in a middle-aged population is extremely rare and requires careful attention for diagnosis; it is almost always discovered through surgery.…”
Get full text

Ossifying Fibroma of Mandible - A Case Report by Gargi Jadaun, A. Bhagwandas Rai, Saeeda Kharodia, Viral Gadhiya

“…Introduction: Ossifying fibromas are rare, non-aggressive benign tumours of the bone, commonly involving the posterior mandible in middle-aged individuals with a female predilection. …”
Get full text

Application of Fibrin Glue in the Treatment of Rectal Fistula by Sergey A. Frolov, Alexandr M. Kuzminov, Dmitry V. Vyshegorodtsev, Vyacheslav Yu. Korolik, Sharof T. Minbaev, Ilya S. Bogormistrov, Evgeny V. Kim

“…Patients with rectal fistulas are frequently represented by the able-bodied middle-aged population group. The disease is extremely rarely observed in children and elderly people. …”
Get full text

Comparing Welfare Regime Changes: Living Standards and the Unequal Life Chances of Different Birth Cohorts by Louis Chauvel

“…These scarring effects can affect specific birth cohorts in countries where the welfare regime provides the context for increasing polarisation between middle-aged insiders and young outsiders. This is characterised by a lack of resilience to early career difficulties faced by cohorts of young adults.…”
Get full text

Writing Against Culture with Online Poker by Jukka Jouhki

“…When the NHL strike (2004–2005) in North America created an  cute need for television re-scheduling, poker tournaments filled the empty programming slots. A stale game of middle-aged men turned into an exciting, familiar hobby with a global reach. …”
Get full text

Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient by Ramneek Kaur, Naveen Mittal, Ankita Soni, Harpreet Kaur

“…We present a case of a middle-aged immunocompetent man with primary adrenal insufficiency and bilateral adrenal lesions, splenomegaly, and miliary mottling in the lungs on imaging. …”
Get full text

A Case Report on Kimura Disease by Biswajit Adhikari, Sarmila Sen, Somnath Saha

“…This disease is endemic in middle-aged Asian males and is seen sporadically in the non-Asian population.There is no standardized treatment protocol present for Kimura Disease. …”
Get full text

An association between average daily sleep duration and gallstones in US adults by Yong Fang, Qiuyuan Xu, Jia Xu, HaiHua Wang

“…Interestingly, the inflection points were observed among middle-aged adults (40–60 years) and individuals with diabetes. …”
Get full text

Targeting TRPM3 as a potential therapeutic approach for autosomal dominant polycystic kidney disease by Hüseyin Gül, Jamie A. Davies

“…Abstract Cystic diseases, especially autosomal dominant polycystic kidney disease (ADPKD; incidence approx. 1/1000), are a leading cause of renal failure, caused by appearance and growth of renal cysts that can lead to renal failure in middle age. Most ADPKD cases are caused by mutations in PKD1 or PKD2, encoding polycystin-1 (PC1) and polycystin-2 (PC2). …”
Get full text

Impact of Driver Age and Behavior on the Effectiveness of ADAS in Cyclist Safety on Rural Roads: A Simulator Study by Nouman Usama, Ahmed M. Al-Wathinani, Krzysztof Goniewicz, Sami Babar

“…Utilizing a driving simulator, the study analyzed the overtaking maneuvers of 300 male participants, categorized by aggressive and passive driving styles, across three age groups: young (20–34), middle-aged (35–49), and older (50–64) drivers. Results showed that younger drivers exhibited more dynamic and erratic behaviors, with significant variations in lateral control (LC) and time to danger (TTD). …”
Get full text