Human microbiome, applied to clinical practice by V. T. Ivashkin, K. V. Ivashkin

“…The main features of human microbiome include: great variety at the level of genus and at the level of species, varying modes of diversification within samples, variability of microbiome of separate individuals is much less in comparison to interindividual variability, metabolic pathways remain unchanged until the patient is healthy, the lack of pathogenic bacteria in healthy microbiomes serves as microbiota alteration evidence in the state of disease. …”
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Fingertip traumatic amputations in children. Treatment with semiocclusive foil dressings-preliminary results by Dimitar Trizlov, Dimitar Raykov, Stoyan Ivanov, Ivan Trizlov

“…Materials and Methods: The study involved 6 patients between the ages of 8 and 15 with fingertip amputations of the hand. …”
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Interrelation of irritable bowel syndrome and bacterial overgrowth: is there any? by Yu. A. Kucheryavy, S. V. Cheryomushkin, Ye. A. Mayevskaya, Ye. A. Sutugina

“…The evidential base is generated according to the studies showing high frequency of pathological breath tests in patients with IBS in comparison to healthy patients, however at IBS the rapid intestinal transit can promote false-positive results of breath tests. …”
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ARE QUALITY INDICATORS IMPORTANT IN COLONOSCOPIES? ANALYSIS OF 3,076 EXAMS IN A PRIVATE TERTIARY SERVICE IN SOUTHEASTERN BRAZIL by Adriana Borgonovi CHRISTIANO, Danielle Rossana Queiroz Martins BONILHA, Mauro Augusto MARCHIORI JUNIOR, Priscilla de Sene Portel OLIVEIRA, Maria de Lourdes Setsuko AYRIZONO

“…RESULTS: During the period, 3,686 colonoscopies were performed, and 3,076 were included in the analysis. The mean patient age was 57.2 years, and most patients were female (53.5%). …”
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STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes by Zoe King, Sudhamsh Reddy Desai, David A. Frank, Aditi Shastri

“…By integrating findings from recent preclinical and clinical studies, this review provides insights into the evolving landscape of STAT-targeted therapies, highlighting the promise of these approaches in enhancing treatment efficacy and improving patient outcomes in high-risk hematologic malignancies.…”
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Medication use and potential drug-drug interactions in a general surgery clinic: A descriptive studyMain points by Sevgi Teker Yıldırım, Şevket Cumhur Yeğen, Songül Tezcan

“…Results: The study involved 95 patients, with a median age of 54 (ranging from 19 to 86). …”
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Hematological manifestations of autoimmune gastritis by Ye. A. Losik, V. T. Ivashkin

“…To estimate hematological disorders in patients with high titer of anti-parietal cell antibodies (APCA). …”
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THORACIC SPINE CANAL STENOSIS WITH CAUDA EQUINE SYNDROME: CASE REPORT by Primadenny Ariesa Airlangga, Arifin Arifin

“…Thoracal MRI examination shows severe spinal stenosis at 11th-12th thoracal vertebra with ligamentum flavum hypertrophy. Second patient, a 70-year-old man complained of weak legs since 1 week, accompanied by low back pain, numbness in the buttocks, and difficulty defecating. …”
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PRKD2 as a novel target for targeting the diabetes–osteoporosis nexus by Rongjin Chen, Chenhui Yang, Hefang Xiao, Ao Yang, Changshun Chen, Fei Yang, Bo Peng, Bin Geng, Yayi Xia

“…By employing the Mfuzz time-series gene clustering method combined with transcriptome sequencing of patient serum, we systematically delineated gene expression patterns during the transition from a healthy state through DM to DMOP. …”
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Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the child by O. K. Botvin'yev, A. I. Kolotilina, I. N. Razumovskaya, A. V. Yeremeyeva

“…All patients underwent complex clinical and laboratory, instrumental and immunologic investigation. …”
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Balancing between being the most valuable player (MVP) and passing the ball: a qualitative study of support when living with chronic pain in Sweden by Markus Saarijärvi, Sara Wallström, Inger Ekman, Mari Lundberg, Veronica Lilja, Vivi-Anne Segertoft

“…Objective This study aimed to elucidate the meaning of lived experiences of support from social networks and the healthcare sector in persons with chronic pain.Design A qualitative, phenomenological hermeneutic method was used to analyse interview data.Setting Participants were recruited from patient organisations in Sweden.Participants Ten (seven women, two men and one non-binary) individuals with chronic musculoskeletal pain were included.Findings The meaning of lived experiences of support in persons with chronic pain involves balancing between being the most valuable player (MVP) and passing the ball, meaning balancing between being a capable person and accepting support to be that capable person.Conclusion For participants who lived with chronic pain, support means balancing between being capable (the MVP) and willing to accept support (passing the ball), which aligns with the concept of person-centred care. …”
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Pathogenesis of Functional Biliary Pain and Pharmacology of Trimebutin by E. L. Bueverova, O. Yu. Zolnikova, N. L. Dzhakhaya, A. V. Sedova, V. Т. Ivashkin

“…Biliary pain is one of the most frequent reasons for patients to see a doctor. The diagnosis of functional disorder of the gallbladder and Oddi's sphincter is legitimate only after the exclusion of organic causes from both the gastrointestinal tract and other organs and systems. …”
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Treatment approaches for idiopathic retroperitoneal fibrosis: a systematic review with meta-analysis by Annik Steimer, Mike O. Becker

“…Results The search resulted in a total of 3818 articles, of which 108 were selected for qualitative analysis involving a total of 1408 patients. For the meta-analysis 83 studies were included involving 1044 patients. …”
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Understanding the causes of intravenous medication administration errors in hospitals: a qualitative critical incident study by Darren M Ashcroft, Richard N Keers, Jonathan Cooke, Steven D Williams

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Prolotherapy Perineural Injection in Carpal Tunnel Syndrome with Bifid Median Nerve: A Case Report by Tresna Angga Basunanda, Arfano Januar Sangkai

“…USG examination showed that the patient had a bifid median nerve anatomy variaton. …”
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Hikikomori, a risk factor for life-threatening malnutrition: a case report of an emergency within the vulnerability by Nicola Artusi, Emanuele Russo, Gianmaria Valeri, Marzia Tecchiolli, Franco Cominotto

“…Case  report:    We present the case of a young man admitted to the emergency department with life-threatening malnutrition and anemia after prolonged self-isolation following  cyberbullying  episodes. The patient was found in critical condition, suffering from shock and multiorgan failure. …”
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Diastolic dysfunction of myocardium and change of <i>Q–T</i> interval at chronic hepatitis C by A. A. Konysheva, Ye. A. Saginova, S. V. Moiseyev, T. N. Krasnova, D. T. Abdurakhmanov

“…To study the functional changes of cardio-vascular system in patients with viral liver diseases.Material and methods. …”
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Awareness of prostate cancer and its screening tests in men in the Middle East: A systematic review and meta-analysis by Nawaf S.A. Mohamed, Joud M.O. Asfari, Samar M.A. Sambawa, Rima M.D. Aljurf, Kholoud A.A. Alsaygh, Assad M. Arafah

“…To improve early detection and patient outcomes, comprehensive education and culturally sensitive communication strategies are necessary.…”
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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets by Claire Vinel, James Boot, Weiwei Jin, Nicola Pomella, Alexandra Hadaway, Charles Mein, Nicolae Radu Zabet, Silvia Marino

“…We also identify novel epigenetically regulated druggable target genes on a patient-specific level, including SMOX and GABBR2.…”
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Levels of burnout and its association with resilience and coping mechanisms among orthopaedic surgery residents: a single institution experience from Singapore by Sean WL Ho, Ernest BK Kwek

“…Introduction: Burnout has implications for surgeon wellbeing and patient care. We aimed to: (a) describe burnout levels among orthopaedic surgery residents in an Accreditation Council for Graduate Medical Education-International (ACGME-I) accredited programme; and (b) determine associations between burnout levels and resident characteristics, resilience and coping mechanisms. …”
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