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Policy brief: Optimising antimicrobial usage in paediatric inpatient hospital settings
Published 2024-04-01Get full text
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Exogenous cystine increases susceptibility of drug-resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels
Published 2025-02-01“…IntroductionAntibiotic overuse has caused the development of bacterial resistance, which is a major threat to public health. Intracellular metabolic processes are essential for maintaining the normal physiological activities of bacteria, and an increasing body of research has demonstrated a significant association between metabolic alterations and the development of drug resistance. …”
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Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial)
Published 2025-02-01“…Introduction Methamphetamine use disorder is a significant public health concern. No pharmacological treatment options currently exist for methamphetamine use disorder, and psychotherapy is only moderately effective. …”
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Development of a Sensitive Quantum Dot-Linked Immunoassay for the Multiplex Detection of Biochemical Markers in a Microvolumeric Format
Published 2025-02-01“…Ursule Kalvaityte,1 Edvardas Bagdonas,1 Gailute Kirdaite,2 Asta Kausaite-Minkstimiene,3,4 Ilona Uzieliene,1 Almira Ramanaviciene,3,4 Anton Popov,3,4 Greta Butkiene,1,5 Vitalijus Karabanovas,1,5 Jaroslav Denkovskij,1 Ali Mobasheri,1,6– 8 Eiva Bernotiene1,9 1Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, LT-08406, Lithuania; 2Department of Personalised Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania; 3Department of Immunology and Bioelectrochemistry, State Research Institute Centre for Innovative Medicine, Vilnius, LT-08406, Lithuania; 4NanoTechnas - Center of Nanotechnology and Materials Science, Faculty of Chemistry and Geosciences, Vilnius University, Vilnius, LT-03225, Lithuania; 5Biomedical Physics Laboratory, National Cancer Institute, Baublio 3b, Vilnius, LT-08406, Lithuania; 6Research Unit of Health Sciences and Technology, Faculty of Medicine, University of Oulu, Oulu, 90014, Finland; 7World Health Organization Collaborating Center for Public Health Aspects of Musculoskeletal Health and Aging, Université de Liège, Liège, B-4000, Belgium; 8Department of Joint Surgery, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, People’s Republic of China; 9Faculty of Fundamental Sciences, Vilnius Gediminas Technical University, Vilnius, LT-10223, LithuaniaCorrespondence: Eiva Bernotiene, Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Santariskiu G. 5, Vilnius, LT-08406, Lithuania, Tel +37068377130, Email [email protected]: For the diagnosis of various diseases, simultaneous sensitive detection of multiple biomarkers using low sample volumes is needed. …”
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Impact of Population-Based Screening for Diabetes and Prediabetes Among 67-Year-Olds Using Point-of-Care HbA1c on Healthcare Ultilisation, Results from the VISP Cohort
Published 2025-02-01“…Jesper Winkler Andersen,1,2 Annette Høgh,1,3 Jes Sanddal Lindholt,1,3– 6 Rikke Søgaard,5 Henrik Støvring,3,7 Knud Bonnet Yderstræde,5,8 Annelli Sandbæk,9– 11 Marie Dahl1,3– 5 1Vascular Research Unit, Department of Vascular Surgery, Viborg Regional Hospital, Viborg, Denmark; 2Department of Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; 3Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; 4Department of Cardiothoracic and Vascular Surgery, Odense University Hospital, Odense, Denmark; 5Department of Clinical Research, University of Southern Denmark, Odense, Denmark; 6Elite Centre of Individualized Treatment of Arterial Diseases (CIMA), Odense University Hospital, Odense, Denmark; 7Department of Biomedicine, Aarhus University, Aarhus, Denmark; 8Diabetes Center, Steno, Odense, Denmark; 9Department of Public Health, Aarhus University, Aarhus, Denmark; 10Research unit of General Medical Practice, Aarhus University, Aarhus, Denmark; 11Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, DenmarkCorrespondence: Jesper Winkler Andersen, Vascular Research Unit, Department of Surgery, Viborg Regional Hospital, Toldbodgade 12, Viborg, 8800, Denmark, Tel +45 28118736, Email [email protected]: The present study aims to evaluate the changes in healthcare utilization following population-based screening for diabetes mellitus (DM) using point-of-care HbA1c measurement in the Viborg Screening Program (VISP) cohort, which invites all 67-year-olds in Viborg, Denmark, for cardiovascular disease (CVD) and DM screening.Patients and Methods: We conducted a cohort study using data from VISP and Danish national health registers. …”
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Molecular characterization of ST15 carbapenem-resistant Klebsiella pneumoniae isolated in a single patient
Published 2025-01-01“…Background: The carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a serious threat to antibiotic applicability and public health. During treatment, K. pneumoniae (KP) frequently exhibits shifts in drug-resistant phenotypes, complicating clinical treatment as it transitions from sensitivity to resistance. …”
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Évaluation de la prescription et de l’utilisation des benzodiazépines dans la ville de Sidi Bel-Abbès
Published 2022-12-01“… Abstract Introduction-A high consumption of benzodiazepines (BZDs) has been noticed sometimes outside the rules of prescription recommendations, which makes their consumption a major public health problem. The present study aimed to evaluate the prescription and use of BZDs in Sidi Bel-Abbès city. …”
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Long-term trends and patterns in ultra-processed food consumption among Korean adults from 1998 to 2022
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Responsabilidades civiles, éticas y legales del profesional de enfermería en Caaguazú, Paraguay
Published 2025-02-01“…The population was made up of 130 nursing professionals who perform functions in the healthcare and public health areas. The technique used was the survey using an instrument with 25 questions, the questionnaire was validated through pilot testing and review by a panel of experts. …”
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Incidence and temporal trends of out-of-hospital cardiac arrest in Shenzhen, China (2011–2018)
Published 2025-03-01“…Background: Out-of-hospital cardiac arrest (OHCA) is a significant global public health issue, few studies describe characteristics and trends in China. …”
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Assessing Mental Illness Referral Request Acceptance: A Nationwide E-Referral Data From Saudi Arabia
Published 2025-02-01“…Abdullah A Alharbi,1 Nawfal A Aljerian,2– 4 Hani A Alghamdi,5 Meshary S Binhotan,4,6 Ali K Alsultan,2 Mohammed S Arafat,2 Abdulrahman Aldhabib,2 Ahmed I Aloqayli,2 Eid B Alwahbi,2 Ronnie D Horner7 1Family and Community Medicine Department, Faculty of Medicine, Jazan University, Jazan City, Kingdom of Saudi Arabia; 2Medical Referrals Centre, Ministry of Health, Riyadh, Kingdom of Saudi Arabia; 3Emergency Medical Services Department, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Science, Riyadh, Kingdom of Saudi Arabia; 4King Abdullah International Medical Research Centre, Riyadh, Kingdom of Saudi Arabia; 5Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia; 6Emergency Medical Services Department, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia; 7Health Services Research and Administration Department, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USACorrespondence: Meshary S Binhotan, Emergency Medical Services Department, College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh, 22490, Kingdom of Saudi Arabia, Email [email protected] and Objective: Mental disorders significantly impact quality of life and life expectancy, representing a leading cause of global disease burden. …”
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Review and Prospect of Research on Urban Walking Safety and Environmental Influencing Factors Thereof
Published 2025-02-01“…ObjectiveWalking space is an important part of urban public space, and its spatial quality is a basis for the construction of walkable cities, which directly affects residents’ travel willingness and walking experience.MethodsThis research takes relevant literature on walking safety screened from Web of Science and CNKI databases spanning the period from 1975 to 2022 as research object, and analyzes the distribution characteristics of literature related to the current research on walking safety and environmental influencing factors thereof, as well as such contents as research context and research hotspots.ResultsFirstly, from the perspective of literature distribution, a large number of works of scholars in such fields as traffic engineering, public health and sociology have been cited in literature on walking safety, reflecting that pedestrians’ activity safety, traffic safety and security needs are important directions to promote the research on walking safety. …”
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