Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation. by Dylan Carter-Cusack, Stephen Huang, Sahar Keshvari, Omkar Patkar, Anuj Sehgal, Rachel Allavena, Robert A J Byrne, B Paul Morgan, Stephen J Bush, Kim M Summers, Katharine M Irvine, David A Hume

“…Network analysis revealed a common signature of CSF1R-dependent resident tissue macrophages that includes the components of complement C1Q (C1qa/b/c genes). Circulating C1Q was almost undetectable in Csf1rko rats and rapidly restored to normal levels following BMT. …”
Get full text

Budget Impact Analysis of Darbepoetin Alfa Every 3 Weeks versus Epoetin Alfa Every Week for Cancer Patients with Anemia due to the Effect of Concomitant Myelosuppressive Chemothera... by November McGarvey, Hairong Xu

“…., chemotherapy-induced anemia [CIA]) with erythropoiesis stimulating agents (ESAs), either darbepoetin alfa (DA) once every 3 weeks (Q3W) or epoetin alfa (EA) once every week (QW), for a large US health plan in 2014. …”
Get full text

Analysis of ADR reports of cetuximab based on the FDA adverse event reporting system database by Shuai Zhao, Yan Wang, Xiaoli Deng, Xi Chen, Zhaoyi Lu

“…This study retrospectively analyzed the cases reported in the FDA adverse event reporting system (FAERS) related to the application of cetuximab from 2013 Q1 to 2022 Q4. Disproportionality analyses, including the reporting odds ratio (ROR), the proportional reporting ratio (PRR), the Bayesian confidence propagation neural network (BCPNN), and the empirical Bayesian geometric mean (EBGM) algorithms, were employed to quantify the signals of cetuximab-associated AEs. …”
Get full text

Obesity mediates the association between psoriasis and diabetes incidence: a population-based study by Zuojiao Xu, Kaihua Ma, Yinuo Zhai, Jing Wang, Yan Li

“…A positive relationship was identified between BMI levels and diabetes occurrence among individuals with psoriasis, with a significant difference observed between the highest (Q4) and lowest (Q1) BMI quartiles (P < 0.05). Further analysis using smooth curve fitting demonstrated the consistent association between BMI and diabetes, which was also evident in psoriasis patients. …”
Get full text

Overexpression of NtCET4 gene in tobacco promoted vegetative bud activity and delayed flowering by LONG Junlan, LUO Rui, LUO Xu, ZHANG Lan

“…The overexpressed lines were selected from transgenic lines based on qRT-PCR. The overexpressed plants were transplanted into fields to observe flowering time and leaf numbers. qRTPCR was used to identify relative expressions of NtCET4 before and after flowering. …”
Get full text

The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity. by Liam C Hunt, Michelle Curley, Kudzai Nyamkondiwa, Anna Stephan, Jianqin Jiao, Kanisha Kavdia, Vishwajeeth R Pagala, Junmin Peng, Fabio Demontis

“…Here, we find that E2s have diverse roles in handling a model aggregation-prone protein (huntingtin-polyQ) in the Drosophila retina: while some E2s mediate aggregate assembly, UBE2D/effete (eff) and other E2s are required for huntingtin-polyQ degradation. …”
Get full text

Tiltan and Superclub by Garti, Shimon, Shelah, Saharon

“…We also prove that if $\kappa $ is regular then superclub at $\kappa ^+$ implies $Q(\kappa ^+,\kappa ^+,\kappa ^+)$.…”
Get full text

Shinbrot’s energy conservation criterion for the 3D Navier–Stokes–Maxwell system by Ma, Dandan, Wu, Fan

“…Although the Maxwell equation with hyperbolic nature, we still establish a $L^qL^p$ type condition guarantee validity of the energy equality for the weak solutions. …”
Get full text

Salmonella y tomates: preguntas y respuestas para los consumidores by Max Teplitski, Keith R. Schneider, Michelle D. Danyluk, Claudio F. Gonzalez

“…SL263-SP, a 7-page fact sheet by Max Teplitski, Keith Schneider, Michelle Danyluk, and Claudio Gonzalez, is the Spanish-language version of SL263, “Salmonella and Tomatoes: Q & A for Consumers.” It provides research-supported answers to common consumer questions about the safety of fresh fruits and vegetables in response to the recent outbreak of salmonellosis linked to the consumption of tomatoes. …”
Get full text

Salmonella y tomates: preguntas y respuestas para los consumidores by Max Teplitski, Keith R. Schneider, Michelle D. Danyluk, Claudio F. Gonzalez

“…SL263-SP, a 7-page fact sheet by Max Teplitski, Keith Schneider, Michelle Danyluk, and Claudio Gonzalez, is the Spanish-language version of SL263, “Salmonella and Tomatoes: Q & A for Consumers.” It provides research-supported answers to common consumer questions about the safety of fresh fruits and vegetables in response to the recent outbreak of salmonellosis linked to the consumption of tomatoes. …”
Get full text

FDFT1 inhibits macrophage M1 polarization and promotes colorectal cancer progression by GAO Yuan, HUANG Yulan, ZHAO Kun

“…Methods‍　‍Mouse colorectal cancer MC38 cells were divided into control group (si-NC) and experimental groups (the expression of enzymes in cholesterol synthesis pathway was interfered with siRNA for corresponding targets). RT-qPCR was used to detect the mRNA levels of corresponding targets in MC38 cells after transfection. …”
Get full text

Changes in cancer incidence and stage during the COVID-19 pandemic in 2020–2021 in the Nordic countries by Anna Johansson, Anna Skog, Tom Børge Johannesen, Tor Åge Myklebust, Simon M. Kønig, Charlotte Wessel Skovlund, Lina Steinrud Mørch, Søren Friis, Marnar Fríðheim Kristiansen, David Pettersson, Eva María Gudmundsdóttir, Nanna Margrét Kristinsdóttir, Helgi Birgisson, Sandra Irenaeus, Johan Ahlgren, Mats Lambe, Elli Hirvonen, Janne Pitkäniemi, Giske Ursin

“…Incidence rates also declined in the second pandemic wave (Q1 2021), ranging from –8.6% [–10.2%; –6.9%] (Sweden) to –2.3% [–4.6%; 0.1%] (Norway), and in Sweden also by –3.1% [–4.8%; –1.3%] in the third pandemic wave (Q4 2021). …”
Get full text

Associations between phenol and paraben exposure and the risk of developing breast cancer in adult women: a cross-sectional study by Yao Xiong, Zhiyu Li, Xiong Xiong, Zixuan Luo, Kaixin Zhong, Jiawei Hu, Shengrong Sun, Chuang Chen

“…The results from the weighted multivariable regression models indicated that exposure to elevated concentrations of TRS increased the risk of developing BC by 2.33 (Q2: 95% CI = 1.45–3.75, p < 0.001) and 1.94 times (Q3: 95% CI = 1.21–3.09, p = 0.006), respectively. …”
Get full text

Trunk, Mass Grasp, Knee, and Hip Muscle Performance in CrossFit Participants: Reference Values According to Participants' Sex and Limb Dominance by Ana Luiza R Rodrigues, Renan A. Resende, Livia S. Pogetti, Thiago R. T. Santos, Henrique M. P. Faria, Mauro H. Chagas, Juliana M Ocarino

“…Also, the dominant limb had greater mass grasp strength (p\<0.002), greater KE power at 60º/s (p=0.015), lower H:Q ratio at 60º/s (p=0.021) and 300º/s (p=0.008), and lower KE fatigue (p=0.002)…”
Get full text

Isokinetic Assessment of Knee Flexor and Extensor Strength and Lower Extremity Flexibility Assessment of an NCAA Division III Men’s Soccer Team by Savanna Perkins, Paul Canavan

“…The team's average for left and right H:Q ratios for each speed were 54.4 and 51.4 at 60°/sec and 61.6 and 63.1 at 180°/sec, respectively. …”
Get full text

Healthcare Resource Utilization and Costs Among Patients With Gastroesophageal Reflux Disease, Barrett’s Esophagus, and Barrett’s Esophagus-Related Neoplasia in the United States... by Prateek Sharma, Gary W. Falk, Menaka Bhor, A. Burak Ozbay, Dominick Latremouille-Viau, Annie Guerin, Sherry Shi, Margaret M. Elvekrog, Paul Limburg

“…**Methods:** Adult patients with GERD, nondysplastic BE (NDBE), and BERN (including indefinite for dysplasia \[IND\], low-grade dysplasia \[LGD\], high-grade dysplasia \[HGD\] or esophageal adenocarcinoma \[EAC\]), were identified from a large US administrative claims database, the IBM Truven Health MarketScan® databases (Q1/2015-Q4/2019). Patients were categorized into the corresponding mutually exclusive EAC-risk/diagnosis cohorts based on the most advanced stage from GERD to EAC using diagnosis codes in medical claims. …”
Get full text

Prevalence and spectrum of haemoglobinopathies in females of reproductive age group- A first tertiary care center experience in Punjab, North India by Vikram Narang, Anshul Jain, Sumit Grover, Ankita Soni, Monika Narang, Ashima Taneja

“…Results: During the study period, 72.2% of the females were affected with β-thalassemia trait, followed by HbD Punjab trait (17.8%), HbQ India trait (2.9%), β-thalassemia major (1.8%), and two cases (1.2%) each of HbS trait, HbD Iran trait, and compound heterozygous of HbD Punjab and β-thalassaemia, whereas HbE trait, compound heterozygous of HbQ and β-thalassemia, compound heterozygous of HbJ-variant and β-thalassemia had one case each (0.6%). …”
Get full text

Parchment Glutamine Index (PQI): A novel method to estimate glutamine deamidation levels in parchment collagen obtained from low-quality MALDI-TOF data by Nair, Bharath, Palomo, Ismael Rodríguez, Markussen, Bo, Wiuf, Carsten, Fiddyment, Sarah, Collins, Matthew James

“…During liming, collagen peptides containing Glutamine (Q) undergo deamidation resulting in a mass shift of 0.984 Da. …”
Get full text

Exploring lecturers’ goal-setting using a coaching framework by Anna Carissa Rozzo

Get full text

Some Simple Full-Range Inverse-Normal Approximations by Raymond Koopman

“…Alternate versions of the approximations are also given, with the constants chosen to minimize the maximum relative error in the implied approximate q rather than the maximum absolute error in the approximate z. …”
Get full text