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Bioinformatics screening and clinical validation of CircRNA and related miRNA in male osteoporosis
Published 2025-02-01Subjects: Get full text
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Comprehensive analysis of differential mRNA and circRNA profiles in primary and metastatic pancreatic neuroendocrine tumors
Published 2025-03-01Subjects: Get full text
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Exploring Echinacea angustifolia for anti-viral compounds against Zika virus RNA-dependent RNA polymerase: a computational study
Published 2025-02-01Subjects: Get full text
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Role of microRNA in the risk stratification of ischemic strokes
Published 2025-02-01“…It can be used to identify Stroke-Specific microRNA Signatures, identify diagnostic and prognostic values, and regulate Vascular Inflammation, Endothelial Dysfunction, and Thrombus Formation and Resolution. …”
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Over-Expression of MicroRNA-210 and MicroRNA-185-5p in Normotensive Late-Fetal Growth Restriction: Preliminary Cohort Study
Published 2024-08-01“…This preliminary study evaluates the expression profiles and clinical significance of hypoxia-sensitive microRNA-210 (miR-210) and microRNA-185-5p (miR-185-5p) in placental and maternal circulation. …”
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Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection
Published 2025-02-01“…Results We identified a range of RNA species expressed in EVs secreted by PM cells, including protein-coding RNA (80%), long non-coding RNA (13%), pseudogenes (4.5%), and short non-coding RNA (1.6%). …”
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Long non-coding RNA involved in the carcinogenesis of human female cancer - a comprehensive review
Published 2025-02-01Subjects: Get full text
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Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction
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Multi-locus CRISPRi targeting with a single truncated guide RNA
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Detection by Single-Cell RNA Sequencing of Virally Mediated Skin Diseases
Published 2025-05-01Subjects: Get full text
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Molecular characterization of Pseudomyxoma peritonei with single-cell and bulk RNA sequencing
Published 2025-02-01“…Additionally, we provide bulk RNA-seq datasets from two independent cohorts: 19 fresh frozen tissue samples (12 PMPs) and 34 formalin-fixed paraffin-embedded (FFPE) samples (25 PMPs). …”
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Association of functional variants in miRNA genes with the risk of coronary heart disease
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Feature selection in single-cell RNA sequencing data: a comprehensive evaluation
Published 2024-09-01“… Single-cell RNA sequencing (scRNA-seq) has revolutionized biological and medical research, providing unique insights into the intricate cell-type compositions within various tissues. …”
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A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA
Published 2025-02-01“…Our understanding of the RNA catalytic mechanism will be beneficial for ribozyme’s biotechnological applications and as potential therapeutics against RNA viruses.…”
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Structural basis for RNA-guided DNA degradation by Cas5-HNH/Cascade complex
Published 2025-02-01“…Abstract Type I-E CRISPR (clustered regularly interspaced short palindromic repeats)–Cas (CRISPR-associated proteins) system is one of the most extensively studied RNA-guided adaptive immune systems in prokaryotes, providing defense against foreign genetic elements. …”
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D-stem mutation in an essential tRNA increases translation speed at the cost of fidelity.
Published 2025-02-01“…The efficiency with which aminoacyl-tRNA and GTP-bound translation elongation factor EF-Tu recognizes the A-site codon of the ribosome is dependent on codons and tRNA species present in the polypeptide (P) and exit (E) codon sites. …”
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Developing mRNA lipid nanoparticle vaccine effective for cryptococcosis in a murine model
Published 2025-02-01“…These results support the promise of mRNA-LNP vaccines against fungal diseases.…”
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Target miRNA identification for the LPL gene in large yellow croaker (Larimichthys crocea)
Published 2025-02-01“…Abstract MicroRNA (miRNA), a conservatively evolved single-stranded non-coding RNA, exerts pivotal control over the appearance of target genes and several biological processes. …”
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