KLF5 silencing restrains proliferation, invasion, migration and angiogenesis of gallbladder carcinoma cells by transcriptional regulation of PDGFA by Xiaowei Lu, Kui Hu, Dandan Zhang, Xuefeng Yin, Jifeng Nie, Kai Zhao

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Liver cystic echinococcosis: A retrospective study on the demographics and clinical profile of patients managed at a single tertiary institution in central Eastern Cape Province, S... by A Govindasamy, P R Bhattarai, J van Niekerk, J John

“…A 4-year (2019 - 2022) retrospective clinical record review study was conducted on patients presenting with liver CE to the Department of Surgery at Frere Hospital. The demographics, clinical characteristics and management of patients with liver CE are reported. …”
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Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis by Qinzhen Lu, He Ling, Yonghui Lao, Junjie Liu, Wei Su, Zhao Huang

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Unveiling the new chapter in nanobody engineering: advances in traditional construction and AI-driven optimization by Jiwei Liu, Lei Wu, Anqi Xie, Weici Liu, Zhao He, Yuan Wan, Wenjun Mao

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Assessment of long-term changes in subvalvular aortic stenosis in patients following transcatheter aortic valve implantation by Vladlen V. Bazylev, Andrey B. Voevodin, Alexey S. Masyutin

“…Long-term outcomes of TAVI included a significant decrease in hypertrophy of IVS (p=0.031) IVS thicknesses mainly decreased over the period up to 24 months after surgery. Cox regression analysis found that each year of patient’s age increased the risk of no postoperative decrease in IVS thickness after surgery by 12% every month. …”
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Efficacy and fibrinogen correlations of defibrinogen therapy in idiopathic sudden sensorineural hearing loss by Bing Wang, Wen Zhang, Jin Zhang, Qimei Yang, Bing Han, Hui Liu, Ziyu Zhao

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Single-Institution Experience With Nononcologic Total Femoral Replacement by Ryan Ouillette, MD, Kevin Chen, BA, Matthew Dipane, BA, Alexander Christ, MD, Edward McPherson, MD, Alexandra Stavrakis, MD

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Urology care in South Africa: A call for collaboration by J John, A Adam, S Mutambirwa

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Comment on: A Contemporary Analysis of Discharge Disposition Following Total Joint Arthroplasty by Francesco Pegreffi, MD, PhD, Gianluca Costa, MD, Arcangelo Russo, MD, Raoul Saggini, MD

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A Prospective Comparative Study on the Clinical Diagnostic Performance of Blood Inflammatory Markers in Acute Appendicitis [Letter] by Peksöz R, Ağırman E, Atamanalp SS

“…Rıfat Peksöz,1,* Enes Ağırman,2,* Sabri Selçuk Atamanalp1,* 1Department of General Surgery, Atatürk University Research Hospital, Erzurum, Turkey; 2Department of General Surgery, Erzurum City Hospital, Erzurum, Turkey*These authors contributed equally to this workCorrespondence: Rıfat Peksöz, Department of General Surgery, Atatürk University Faculty of Medicine, Erzurum, Turkey, Tel +90 04423447956, Email [email protected]…”
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Clinical benefits of the 5th intercostal incision in uniportal VATS for female patients by Dalin Wang, Zhilin Luo, Jia Ming

“…These findings support the 5th intercostal incision as a preferred approach in this patient population, aligning with precision surgery principles to optimize outcomes.…”
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Selective mid-facial neurectomy using intraoperative nerve monitoring system for post-facial paralysis synkinesis by M. Takemaru, H. Sakuma

“…Each branch of the facial nerve is stimulated during surgery, and nerve resection selection is determined based on the macroscopic findings. …”
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Surgical management of metastatic lesions in the proximal femur: a systematic review by Afrim Iljazi, Mads Sten Andersen, Stig Brorson, Michael Mørk Petersen, Michala Skovlund Sørensen

“…Patients treated surgically for skeletal metastases have poorer overall health compared to other orthopedic patients, with only one-third expected to survive two years post-surgery. Choosing a treatment that minimizes revision risk and ensures the implant outlives the patient is therefore crucial. …”
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IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury by Liwu Zeng, Yaxin Wang, Yongzhou Huang, Wenchang Yang, Pei Zhou, Yaqi Wan, Kaixiong Tao, Ruidong Li

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A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights by Junxi Hu, Junxi Hu, Shuyu Tian, Shuyu Tian, Qingwen Liu, Qingwen Liu, Jiaqi Hou, Jiaqi Hou, Jun wu, Jun wu, Xiaolin Wang, Xiaolin Wang, Yusheng Shu, Yusheng Shu

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Cancer-associated fibroblast-derived COL17A1 promotes gemcitabine resistance and tumorigenesis in pancreatic cancer cells by interacting with ACTN4 by Rongyu Shi, Ning Zhang, Han Li, Hu Zhong, Chengcheng Zhong, Wei Du, Xi Yang

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En plaque meningioma of the temporal bone: A systematic review on the imaging and management of a rare tumor by Arianna Burato, Giuseppe Maruccio, Livio Presutti, Ignacio Javier Fernandez, Gabriele Molteni, Giulia Molinari

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Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction by Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao

“…Methods Male C57BL/6 mice (2 and 17 months old) were randomly assigned to surgery or control groups. The surgery group underwent laparotomy under 1.5% isoflurane anesthesia, while controls received no intervention. …”
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Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells by Peng Wang, Haiyue Zhao, Wei Chen, Yuhui Guo, Shuo Zhang, Xin Xing, Shuai Yang, Fengkun Wang, Juan Wang, Zengwu Shao, Yingze Zhang

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Does a Provider Contact Wristband Reduce Emergency Department Visit Rates Following Hip or Knee Arthroplasty? by David C. Hein, MD, Ajay K. Srivastava, MD, Seann E. Willson, MD, Paul M. Telehowski, MD, Patrick J. Atkinson, PhD, Theresa S. Atkinson, PhD

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